Doctor insights on:
What Does High Levels Of Dhea Mean
DHEA is a mild androgen, produced by the adrenal glands. It is unusual to have a high level of DHEA unless you are supplementing with DHEA.
The good news is that there is no negative feedback mechanism for DHEA, which means that taking it does not affect your own production of it.
It shouldn't cause a problem. Just decrease or stop your supplementation.
PCOS?: An elevated level of dheas may indicate an adrenocortical tumor, adrenal cancer, or adrenal hyperplasia. An increased level of dheas is not diagnostic of a specific condition; it usually indicates the need for further testing to pinpoint the cause of the hormone imbalance. Polycystic ovarian syndrome:dheas may be elevated but may also be normal as this disorder is usually related to ovariaandrogen. ...Read more
Context: Elevations in dheas may be seen in patients with polycystic ovary syndrome and also in patients with congenital adrenal hyperplasia (and other adrenal dysfunction) and in patients who have early pubic hair development (pediatric). Please speak with your doctor about your elevation to determine what the right course of action is for you. ...Read more
First why elevated?:
DHEAS is the highest concentration steroid hormone. From it is formed all the steroids, including estrogen and progesterone. It can also be associated with elevated male hormones like testosterone that can interfere with cycles and ovulation. It also may affect pregnancy outcomes, especially with girl baby. Elevated DHEAS can come from the adrenal glands, ovaries or both. Glad to discuss ...Read more
What does it mean to have high dhea sulfate levels (elevated adrenal hormones)? What are the problems associated with this? What can it lead to?
By itself: A high (how high) dheas level may mean nothing at all. I don't know why the level would have been drawn in the first place. It can be significantly (not slightly) elevated in a variety of ovarian or adrenal problems, including pcos. It is also stimulated by certain medications. As a solitary finding without other clinical information, however, it has no value. Talk w/the doctor who ordered it, . ...Read more
I am 22 years old and have normal testosterone levels, but high dhea-s. What does it mean? Thanks in advance.
Androgen female: Testosterone and dheas are both male hormones and present in small amounts in normal women testosterone t is produced by ovary and dheas by adrenal if elevated they suggest that gland is the abnormal since dheas is weaker than t it has milder symptoms of androgen excess. ...Read more
What can be the cause of an elevated dhea sulfate level (elevated adrenal hormones) of 599 mcg/dl? What does it mean if it's idiopathic?
Not that high: A dhea-s of 599 (correct -comes from the adrenals) is somewhat increased but will usually not cause problems. It would help to know the reason why it was done. If periods are irregular other tests were probably run and if normal would be reassuring. If periods very irregular and increased facial hair you should definitely see an endocrinologist if you have not done so to look for other things. ...Read more
?: A single lab result of a slightly elevated parameter doesn't make a diagnosis, PCOS is a syndrome, meaning that several clinical and lab/radiological findings should be present together to make a diagnosis, and even having this syndrome doesn't mean you won't have kids of your own, best of luck ...Read more
? Polycystic Ovaries:
One possibility is polycystic ovaries (pcos)
hyperandrogenemia is present in 60% to 80% of women with pcos: 70% have elevated free testosterone, 40% have elevated total testosterone, 25% have elevated dheas. Check with gyn or endocrinologist. ...Read more
Dhea-sulfate test measures the amount of dhea-sulfate in the blood. Dhea-sulfate is a weak male hormone (androgen) produced by the adrenal gland in both men and women.
Excessive dheas maybe found in....Adrenal carcinoma
congenital adrenal hyperplasia
polycystic ovary syndrome
tumor of the adrenal gland. ...Read more
My friend's age is 20.She has high levels of dhea. Can you say causes of that? Hormone level and period are regular. Is that very serious odangerous?
Depends on levels: Dhea is the most abundant adrenal hormone. It's sulfated form is more stable. Labs are not perfect and I wonder why the level was checked in the first place. It may need to be followed and may mean nothing if she is healthy and a symptomatic, but best to have it repeated. If level is too high, more evaluation is needed. ...Read more
I have very high levels of DHEA (480) but borderline low cortisol (3.7). Endocrinologist says PCOS. I worry about adrenal fatigue. Should I worry?
Not normal: First of all there is no such thing as "adrenal fatigue" (not a real disease or condition). With high DHEA, you could have a steroidogenic enzyme deficiency causing congenital adrenal hyperplasia. Do you have any male-pattern hair growth? Irregular or absent periods? Other steroids & steroid intermediates I would check are: 17 (OH)progesterone, Androstenedione, and testosterone; others to check too ...Read more
Adrenal androgen: Hi. DHEA is an adrenal androgen. Do you have male pattern hair growth and/or irregular periods? If you're not taking DHEA, your elevation is coming from your adrenals. This can be seen in some types of congenital adrenal hyperplasia, Cushing's syndrome, and other rarer adrenal problems. I suggest you see an endocrinologist for a proper evaluation including diagnostic tests. Good luck! ...Read more
Labs vary: But usually the normal range is from approx.12-535 for females, so probably nothing to worry about. There are a variety of medications and medical syndromes that can lead to elevated dheas, most commonly PCOS. Discuss w/your doctor. ...Read more
It would take some time and space to answer that here.
I would try to find "Medicine Plus" on the internet and you will find a lot of readable, meaningful information.
If you don't have a computer take a visit to your local library and they will help you. ...Read more
How high is dhea sulfate level considered significantly elevated? What about mild/moderate? In terms of mcg/dl?
It varies based on sex and age.
Typical normal ranges for females are:
ages 18 - 19: 145 - 395 ug/dl
ages 20 - 29: 65 - 380 ug/dl
ages 30 - 39: 45 - 270 ug/dl
ages 40 - 49: 32 - 240 ug/dl
ages 50 - 59: 26 - 200 ug/dl
ages 60 - 69: 13 - 130 ug/dl
ages 69 and older: 17 - 90 ug/dl
typical normal ranges for males are:
ages 18 - 19: 108 - 441 ug/dl
ages 20 - 29: 280 - 640 ug/dl
ages 30 - 39: 120 -. ...Read more
Hi, I am 40 years old and my DHEA level is currently 293. Is this too high? Is it normal that I find it difficult to sleep? Thank you in advance, V
See below: That is a normal value of DHEA. If it is associated with hypertension and elevations of other adrenal steroids, then additional evaluation may be necessary. Difficulty sleeping often reflects anxiety. Activities to relief anxiety may be of help, as is avoidance of caffeine containing drinks. In addition, OTC medications such as Zzzquil may be of help ...Read more
Probably nothing: If you are male, it is of little concern. Dheas is a much weaker androgen than testosterone. If you are female, it depends on how old you are, how high it is and what symptoms you have. Facial hair? Acne? No periods? Infertility? If you have no symptoms or if they are mild, I would not pursue further. If you are symptomatic, would talk to doc about checking adrenals or ovaries. ...Read more
What does it mean if you have normal Cortizol and DHEAS, high 17 OH PRH and high androgens, low ACTH.
What is 17 (OH)PRH?: Hi. I'm not sure what 17 (OH)PRH refers to. There is 17 (OH)progesterone and 17 (OH)pregnenolone in the steroidogenic pathway. Do you mean one of them? And which "androgens" are high? Androstenedione and DHEA? It sounds to me like some sluggish steroidogenic enzyme lumped under "congenital adrenal hyperplasia" (CAH). If so, your ACTH is normal, not low (even though it may be below the "normal rage". ...Read more
My DHEA level is high. A blood test taken 18 mos ago showed a level of 406, and a more recent test shows 380. 55 yr, active, healthy male. Concern?
No concern: DHEA levels vary widely in individuals, as well as throughout the day. Levels are normally higher in men compared to women. It is a precursor hormone made by the adrenal glands. Unless there was a particular concern related to your adrenal glands, it should not have been measured, and certainly should not be a part of a "routine" lab screen. ...Read more
Not really an: Association. It's more likely that the cause of your elevated DHEA levels is responsible but still very well could be unrelated. To be able to better guide you, it would help to understand why a DHEA level was checked, like for an eval for PCOS or too much body hair (hirsuitism) or male pattern baldness in a women? ...Read more
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