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Doctor insights on: What Does Endometrial Tissue Look Like

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Tissue (Definition)

The body is composed of tissue that are classically described as beiing derived from three basic embyonic layers known as the endoderm, mesoderm and ectoderm that then differentiate into the structures that compose the body such as skin, soft tissues, bone, muscle, organs, etc. Stem cells are not differentiated and have the potential to ...Read more


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How much tissue is actually removed in an endometrial biopsy?

How much tissue is actually removed in an endometrial biopsy?

Not much but enough: Very little tissue is removed during an endometrial biopsy but multiple studies show that the amount is adequate to make an accurate diagnosis. The main purpose is to rule out cancer or premalignant lesions called endometrial hyperplasia. ...Read more

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What should be done when pap shows normal endometrial tissue on day 8 of cycle?

What should be done when pap shows normal endometrial tissue on day 8 of cycle?

Probably nothing: It is not unusual to find endometrial cells on a pap smear in the first 14 days of the menstrual cycle. When these cells are found in women over 40, they may prompt additional testing, including an endometrial biopsy to make sure there is no endometrial pathology. ...Read more

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Diagnosis on my endometrial biopsy states: no tissue recovered after routine processing. What does that mean?

Diagnosis on my endometrial biopsy states: no tissue recovered after routine processing. What does that mean?

See below: The biopsy did not recover enough tissue for processing for microscopic examination. Your endometrium may be so atrophic that it did not yield tissue on biopsy or it may have been a technical problem. Please discuss the matter with your doctor to see if an other attempt at biopsy is warranted. ...Read more

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What can cause there to be less endometrial tissue in the uterus than normal?

What can cause there to be less endometrial tissue in the uterus than normal?

Endometrial tissue: Usually, endometrium (lining) thins out after menopause or certain procedures such as ablation. I am not sure what else can be causing thin endometrium. What are you symptoms and what does your doc say? ...Read more

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Does HGH (riptropin) make endometriosis worse (increase speed of endometrial tissue growth)?

Does HGH (riptropin) make endometriosis worse (increase speed of endometrial tissue growth)?

Hard to say: I doubt there are any good studies discussing the use of human growth hormone on endometriosis. Were you prescribed human growth hormone by a doctor? If so they would need to explain the logic. ...Read more

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Endometrial biopsy 9mm w/scant tissue sample no atypical cells but Dr. wants 2nd biopsy. Wasn't enough tissue to make definite diagnosis? Concerning?

Do not worry: Please follow your doctor's advice and get a second biopsy. There was not enough tissue in the first one for making a diagnosis. Excluding disease by having a second biopsy will provide peace of mind. ...Read more

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I have had some endometrial tissue on my tissue when i wipe seems quite large amount i took 150 Clomid (clomiphene) ad 5 18mm flicles do you think this is why ?

I have had some endometrial tissue on my tissue when i wipe seems quite large amount i took 150 Clomid (clomiphene) ad 5 18mm flicles do you think this is why ?

Not sure: 5 follicles of 18 mm is alot and you should probably avoid intercourse in order to prevent multiples. But the tissue could be endometrium - however it doesn't really affect your chance of pregnancy. ...Read more

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Can endometrial cancer look like adenomyosis on ultrasound?

Can endometrial cancer look like adenomyosis on ultrasound?

Possibly: Endometrial cancer in the early stages can appear as a widened endometrial strip on ultrasound. This can mimic adenomyosis. If there is bleeding, this should be evaluated by a gynecologist and perhaps with a d&c. ...Read more

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Can endometrial cancer look like a normal endometrium in secretory phase? Or are there usually other sonographic features? What stage would this be?

Can endometrial cancer look like a normal endometrium in secretory phase? Or are there usually other sonographic features? What stage would this be?

Yes: Ultrasound is not a good predictor for endometrial cancer. That requires a biopsy. Ultrasound may indicate which women need a biopsy depending on their age and clinical circumstances. At age 24, women are at rare risk of endometrial cancer. ...Read more

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Is it normal to have discharge and pass tissue 8 weeks after endometrial ablation?

Is it normal to have discharge and pass tissue 8 weeks after endometrial ablation?

This is not uncommon: The tissue you described is the residual tissue burned during the ablation. I've heard it described by novasure patients like that. It's also not uncommon to have some bleeding after an endometrial ablation. Sometimes regular periods may return after several weeks to years. It is more common to have light bleeding. You should discuss this with your doctor at a future visit. It is not urgent. ...Read more

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Histological section shows mainly decidualised endometrial tissue with hyperplastic glandular component specimen: uterine evacuation?

Histological section shows mainly decidualised endometrial tissue with hyperplastic glandular component

specimen: uterine evacuation?

Hyperplasia: The sample you describe is suggestive of overgrowth of tissue in the uterus due to irregular menstrual cycles. It is seen in women who go for > 6 months without bleeding and suggests overstimulation due to estrogen effect. If left untreated, it could lead to endometrial cancer. Still, it is very slow growing but needs to be monitored. ...Read more

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Thickened lining, Endometrial biopsy was benign but scant tissue sample. Dr says repeat biopsy in 30 days or do D & C & hysterscopy. How do I decide?

Thickened lining, Endometrial biopsy was benign but scant tissue sample. Dr says repeat biopsy in 30 days or do D & C & hysterscopy. How do I decide?

Discuss with doctor: This decision will need to be made by you and your doctor together. The sonogram should be reviewed to determine the thickness and appearance of the endometrial lining. If there are concerns that adequate sampling was not obtained by biopsy then direct visualization by Hysteroscopy may be warranted. ...Read more

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History of lynch syndrome. Sisters endometrial biopsy said limited tissue available, but benign. Should it be redone to rule out cancer if symptomatic?

History of lynch syndrome. Sisters endometrial biopsy said limited tissue available, but benign. Should it be redone to rule out cancer if symptomatic?

Lynch syndrome: Lynch syndrome is an inherited condition that increases your risk of colon cancer and other cancers including endometrial cancer in women. If your sister is symptomatic and does have Lynch syndrome a suboptimal biopsy is not sufficient to rule out endometrial pathology. Further workup is warranted. ...Read more

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Is it normal to see endometrial tissue on a pap smear right after period ends?

Is it normal to see endometrial tissue on a pap smear right after period ends?

it is normal, howeve: Exfoliated endometrial cells are commonly seen in specimens, obtained during the proliferative phase of the menstrual cycle. However, endometrial cells have been considered a potential harbinger of endometrial adenocarcinoma when seen in cervical/vaginal cytology preparations of postmenopausal woman.
In a woman 40 years old or older endometrial cells should be reported and follow up need. ...Read more

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Can a doc just look at tissue from d & c and say that it's probably not endometrial cancer?

Can a doc just look at tissue from d & c and say that it's probably not endometrial cancer?

No: He / she is free to look but visuals on D&C products are famously unreliable. The pathologist needs to look, and if you have any doubts, you can it read by several of us. ...Read more

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Endometrial biopsy done because uterine lining 9mm thick. Benign, but Dr only able to get scant tissue sample. Why would that happen?

Aspiration device: If your MD used a aspiration endometrial biopsy device then a small sampling was all that was needed to give a benign "diagnosis." The "olden days" in office scraping is usually no longer done unless it was a D & C in a surgical environment. ...Read more

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Is it possible that a vaginal ultrasound will misdiagnose a endometrial polyp? Is it possible this is scar tissue from a fiberoil i had removed?

Is it possible that a vaginal ultrasound will misdiagnose a endometrial polyp?  Is it possible this is scar tissue from a fiberoil i had removed?

Polyp: Appearance of lesions on imaging is often suitable as a screening test, but as noted by the other physician's answer it could very well be something else. A biopsy will tell with certainty, as a polyp, leiomyoma, scar and hyperplasia, etc, all have very characteristic features on pathology. ...Read more

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Doctor. Can non-pregnant girl pass endometrial tissue as strawberry sized transparent round sac in period discharge? Thanks!

Doctor. Can non-pregnant girl pass endometrial tissue as strawberry sized transparent round sac in period discharge? Thanks!

Endometrial Tissue: Yes, this may be normal. I would imagine that the lining of the uterus was very thick and the clot you passed is normal. This may happen more frequently in patients with irregular menstrual cycles. If this continues to happen, you should talk to your doctor. ...Read more

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I had 8cm ovarian cyst and endometrial tissue removed. Is it necessary to take hormones such as lupron (leuprolide) to prevent a reoccurence?

I had 8cm ovarian cyst and endometrial tissue removed. Is it necessary to take hormones such as lupron (leuprolide) to prevent a reoccurence?

No: Lupron (leuprolide) will help prevent recurrence while you are on it. However, Lupron (leuprolide) is usually used short term and it may recur after you stop it. Drugs such as birth control pills can be used long term and so may be more helpful. Still, going on hormones after surgery is not absolutely necessary. ...Read more

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On 8/30 + 9/20 i had 80mg kenalog epidural injections. Lmp 8/16. On 9/16 i started spotting continuously on 10/14 at routine gyn visit i had a cervical polyp removed (path showed it was endometrial tissue) i started progesterone 10 mg x 14 days. Still no

On 8/30 + 9/20 i had 80mg kenalog epidural injections. Lmp 8/16. On 9/16 i started spotting continuously on 10/14 at routine gyn visit i had a cervical polyp removed (path showed it was endometrial tissue) i started progesterone 10 mg x 14 days. Still no

I : I am assuming you have had a pregnancy test during this, if not then your doctor should perform one if there is any possibility. There are many causes of spotting, did your doctor think that the cervical polyp or its removal was causing your spotting? Also spotting can be caused by our hormones being "out of whack", this is called dysfunctional uterine bleeding. Usually progsterone will get you back into a rhythm but it sounds like that didn't happen. I do think your doctor's ideas are good including the sonohysterogram. I do not think the steroids are related to the spotting. ...Read more

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What will an endometrial biopsy feel like?

What will an endometrial biopsy feel like?

Cramping: The procedure is variably uncomfortable for different patients, but generally quite tolerable. Some patients may have some discomfort or cramping, during or several hours later, and may have some vaginally spotting. However, most effects are mild and very temporary. ...Read more

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What is an endometrial hyperplesia?

What is an endometrial hyperplesia?

Very early: precancerous changes to the endometrium (lining inside the uterus). If left alone, it can progress on to endometrial cancer. There are also different levels of hyperplasia (complex, with atypia). Don't ignore it --- it is easy to treat medically. ...Read more