Top
30
Doctor insights on: What Does Elevated Lipase Mean

Share
1

1
What does an elevated lipase and amylase mean?

What does an elevated lipase and amylase mean?

Can be pancreas infl: Amylase: enzyme made by pancreas and salivary glands. Elevation can be seen with pancreatitis, mumps, vomiting/bulimia sometimes with other GI (gallbladder, ulcer), gyn issues. Lipase is a somewhat more specific pancreatic enzyme. Mild elevations non specific, very high more specific marker of pancreatic inflammation. Kidney disease screws up the values. Incr. In cystic fibrosis, celiac, . ...Read more

Dr. Todd Igel
353 doctors shared insights

Lipase (Definition)

Lipases, such as lipoprotein lipase and endothelial lipase, are enzymes that breakdown circulating triglycerides (tg). Specifically, lipases degrade tg rich lipoproteins including chylomicrons, very low density lipoprotein (vldl) and remnant particles produced by breakdown of chylomicron and vldl particles. Decreased lipase function leads to accumulation of ...Read more


2

2
My lipase levels are elevated. What can this mean?

Maybe nothing: A mild elevation of serum lipase generally means nothing whatever. Even taking an Ibuprofen tablet may raise the level. The reference range is simply what most folks have. Lipase is assayed primarily to rule out acute pancreatitis, which is not a subtle disease and in which lipase is usually several times above the top of the reference range. ...Read more

3

3
Over past two yrs my lipase has been slightly elevated by 20 points or less. Now it's 40 points elevated. Does this mean it's cancer?

Over past two yrs my lipase has been slightly elevated by 20 points or less. Now it's 40 points elevated. Does this mean it's cancer?

Not a reliable test: Lipase is not a particularly useful test. So my question to you is... why did you get it checked in the first place? Have you had any elevation of Amylase or any history of Acute Pancreatitis?? If you give us your medical history we can be more helpful to you. ...Read more

4

4
Elevated lipase level two days in row. Recent VSG surgery. No pain or other symtpoms. Just lipase. Does this mean cancer?

Elevated lipase level two days in row. Recent VSG surgery. No pain or other symtpoms. Just lipase. Does this mean cancer?

Pancreatitis or VSG: A vertical sleeve gastrectomy removes about 75% of stomach, including the part that covers a lot of the pancreas. Both surgery in this area and general anesthesia can cause elevations in lipase, which represent pancreatitis. CANCER NEVER ELEVATES LIPASE (very rare cases). Lipase must have been measured because of pain -- no other reason. Could also be a leak or an ulcer. Rec endoscopy & CT. ...Read more

5

5
What does it mean to have elevated conjugated bilirubin but normal total bilirubin? And if it is together with high amylase and borderline lipase?

What does it mean to have elevated conjugated bilirubin but normal total bilirubin? And if it is together with high amylase and borderline lipase?

Gallbladder/pancreas: High amylase with increased lipase can indicate pancreatitis. High conjugated bilirubin indicates hepatobiliary disease. You should go see a gastroenterologist with your lab results. ...Read more

6

6
What does having a high lipase mean?

Pancreatitis: High serum levels of lipase, at about three times the upper limit of normal, is usually associated with pancreatitis. ...Read more

7

7
I have elevated lipase after having eaten, but within normal range after having fasted. Why?

Normal response: Some of the enzyme normally released by the pancreas into the intestine may spill into blood. It is not unique to lipase. Intestine alkaline phosphatase also increases in blood with a meal. For good health - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Drink enough water daily, so that your urine is mostly colorless. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form. Practice safe sex, if you have sex. ...Read more

8

8
What could cause slightly elevated lipase levels?

How elevated?: It would help to know the number. Gall stones and alcohol are the common causes of elevated lipase. ...Read more

9

9
Lipase levels were mildly elevated; what would cause this?

High lipase levels: 33 F from Canada notes lipase levels mildly elevated and asks what could cause this. There are many things that can cause this including pancreatitis, gall bladder stone in pancreatic duct, meds, kidney disease, So you really need to ask the Dr who ordered it to interpret it for you as your team there knows you best. You can also google this. But I recommend uptodate.com 4 best source of med info ...Read more

10

10
What does "amylase is more sensitive and lipase test is more specific" mean?

See below:: Amylase is elevated more often in patients with panreatitis, but elevated amylase, unless substantially high does not mean pancreatitis. When lipase is elevated the person is more likely to have pancreatitis. See this site for general explanation of these terms http://gim.Unmc.Edu/dxtests/reviewof.Htm. ...Read more

11

11
Amylase elevated -250. Lipase is normal. What causes this?? Should I be concerned?

Any symptoms?: Why were these tests ordered? There are many causes of elevated amylase and it would require in person evaluation to ascertain the cause. You may consult this site for information on this topic: https://medlineplus.gov/ency/article/003464.htm For good health - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Drink enough water daily, so that your urine is mostly colorless. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form. Practice safe sex, if you have sex. ...Read more

12

12
Lipase is normal amylase is 15 points higher. Should I be concerned? What do each mean? I'm worried.

Lipase is normal amylase is 15 points higher. Should I be concerned? What do each mean? I'm worried.

Pancreatic Enzymes: Amylase and lipase are enzymes produced by the Pancreas which lies in the upper middle part of abdomen.These enzymes are used in digestion.Amylase converts carbohydrates to glucose and lipase converts lipids to fatty acid.They can get elevated when pancreas is inflamed due to any cause.Your Amylasd is slightly elevated and your doctor must suspected Pancreatitis. Discuss with your doctor about it ...Read more

13

13
What does it mean if your amylase and lipase are high?

Pancreatitis: Amylase and lipase are both enzymes that can be detected in the blood in the setting of pancreatitis. With inflammation or injury to the pancreas, these enzymes are "leaked" and get in to the blood. ...Read more

15

15
My lipase elevated from normal 30-110 to 111. Is it acute pancreatitis? Is there any possibility that it is not pancreatitis?

Not likely: Lipase is very non-specific and the elevation you describe is minimal. Nausea by itself can cause an elevated lipase. Would suggest that you abstain from drinking alcohol for a while. ...Read more

16

16
Lab variation issue - If I have normal lipase values at one lab, but elevated values at a different lab, how do I know which lab is "correct"?

Lab variation issue - If I have normal lipase values at one lab, but elevated values at a different lab, how do I know which lab is "correct"?

Any symptoms?: Why were the tests done? Do you have any symptoms? Both results may be correct as different methods of testing can provide different results. What is the amylase? If the pancreatitis is you concern, a normal amylase would rule that out. For good health - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Drink enough water daily, so that your urine is mostly colorless. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form. Practice safe sex, if you have sex. ...Read more

17

17
How long (days, weeks, months) does lipase stay elevated from onset of acute or chronic pancreatitis? Is Lipase elevated at end stage of pancreatitis?

How long (days, weeks, months) does lipase stay elevated from onset of acute or chronic pancreatitis? Is Lipase elevated at end stage of pancreatitis?

Lipase: The lipase level is usually elevated in acute pancreatitis, and usually not in chronic pancreatitis. It will usually remain elevated as long as the acute pancreatitis remains active, and usually decreases as the pancreatitis improves. This can take weeks, but usually does not. A lot depends on what is causing the pancreatitis, in addition. Good luck. ...Read more

18

18
I'm asymptoic and had EUS due to high lipase. What does this mean "What you have overall is some very NON specific finding that may suggest chronic pancreatitis but NO definite findings."?

I'm asymptoic and had EUS due to high lipase. What does this mean "What you have overall is some very NON specific finding that may suggest chronic pancreatitis but NO definite findings."?

=Test not definitive: There are no perfect tests, & unfortunately these include the ones that we rely upon to tell us if cancer or significant disease is present or not. If there is doubt, or your clinical situation has changed, please don't delay in getting a confirmatory study or second opinion. Ask your doctor to candidly share his concerns & best direct you appropriately. Not all pancreatitis is due to alcohol. ...Read more

See 1 more doctor answer
20

20
Normal lipase levels means healthy pancreas?

Not really: All it means is that you don't have pancreatitis at the time of the blood draw. If the pancreas were damaged by previous episodes of pancreatitis, the lipase would still be normal. ...Read more

21

21
How is it that lipase is elevated when no pancreatic disease?

How is it that lipase is elevated when no pancreatic disease?

No other causes: Of lipase elevation except pancreatitis. You probably had a mild case that went away before you had the test, because it takes several days to a week for lipase test to return to normal. ...Read more

22

22
What % of chronic or acute pancreatitis shows elevated Lipase or Amylase?

Acute tests: A 1998 study found that 100% of patients with acute pancreatitis had an elevated lipase, and 95% had an elevated amylase directly upon admission to the hospital. As their hospitalization continued, those values dropped off and so the tests would be less useful for diagnosis. ...Read more

23

23
What does it mean when it ur lipase level is high and just diagnosed with celiac?

Pancreatitis: High lipase can indicate inflammation of the pancreas (chronic or acute). Talk to your doctor, he/she will explain this to you and come up with follow-up plans. ...Read more

24

24
Serum lipase 100; also elevated urobilinogen. Everything else was normal.. Should i be concerned?

How do you FEEL?: Lab reference ranges are set so that several percent of healthiest fall outside. You are almost certainly fine. ...Read more

26

26
What do you suggest if my lipase level is 29 u/l the standard range of that blood test is <=58 does this mean my lipase is low or normal?

Normal: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, your lipase level is normal. Lipase levels below the "normal" limit are not abnormal. ...Read more