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Doctor insights on: What Does Brca 1 Stand For

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What does the brca in brca1 stand for?

What does the brca in brca1 stand for?

Breast Cancer: Women w/ 2+ immediate family members w/ a hx of breast/ovarian CA at 50% chance of developing breast cancer. If you have it, get screened with CA-125 blood test, ultrasound, mammogram/MRI, usually starting at age 30. Surgery after childbearing. ...Read more

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If a brca 1-2 test comes back positive, is a bilateral mastectomy the best option?

If a brca 1-2 test comes back positive, is a bilateral mastectomy the best option?

Risk reduction: The "best" option is a personal choice. Options to lower breast cancer risk for patients with a BRCA1 or BRCA2 mutation include: -bilateral mastectomy which removes most but not all of the breast cells, and reduces risk the most (by 90-95%) -breast MRI and mammogram does not reduce risk but finds breast cancer early when it is more treatable -chemoprevention to prevent getting breast cancer ...Read more

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My 34yr sister had brca1and2 testing.Her brca 2 sequencing back positive as "likely pathogenic".What does that mean?Negative for brca 1 sequenc/depdup

My 34yr sister had brca1and2 testing.Her brca 2 sequencing back positive as "likely pathogenic".What does that mean?Negative for brca 1 sequenc/depdup

Genetic counseling: Brca mutations lead to high risks for breast and ovarian cancer, a genetic counselor can assist with explanations of the testing and implications. ...Read more

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What is my risk for ovarian cancer is I have the brca-1 gene?

What is my risk for ovarian cancer is I have the brca-1 gene?

54 %: Women with a brca1 mutation have a 54% of getting ovarian cancer during their lifetime. This risk can be reduced to less than 5% by having both ovaries removed. ...Read more

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Found out I am positive for mutation in brca 1 gene advice needed please?

Found out I am positive for mutation in brca 1 gene advice needed please?

Life planning: This is something to discuss closely w/ your MD. Ovarian CA more likely w/ BRCA1 than BRCA2. Women w/ either BRCA have >50% chance of developing breast cancer. If you have it, get screened with CA-125 blood test, ultrasound, mammogram/MRI, usually starting at age 30. Surgery after childbearing includes removal of the uterus, ovaries, and fallopian tubes, as well as mastectomy. Good luck. ...Read more

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I have a complex multi septated ovarian cyst at 9.5 x 5.6 x 6.3 CM Is that something to be concerned about ? BRCA 1 family history, I tested Negative

I have a complex multi septated ovarian cyst at 9.5 x 5.6 x 6.3 CM Is that something to be concerned about ? BRCA 1 family history, I tested Negative

Yes: While it is impossible to predict whether or not ovarian cysts/masses are benign or cancer, usually large ones need to be dealt with surgically. May want to see a gyn oncologist for an opinion since they deal with this frequently. Cancer would be very unusual in a 23 year old. Hope this helps! ...Read more

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Hi, can you recommend a company that can test me for the brca 1 and 2, that offers international service? My mother died from ovarian cancer at age 57

Hi, can you recommend a company that can test me for the brca 1 and 2, that offers international service? My mother died from ovarian cancer at age 57

Not that simple: Just your mother's ovarian cancer is not enough to qualify, for genetic screening. Have to meet other criteria myriad genetic lab has patent on brca i & ii testing , through your doctor out side usa can be tested , by contacting mblom@myriod.Com and it is expensive ( most of med insurances will not cover ). ...Read more

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About the brca-1 gene (breast cancer gene)...If a male is a carrier for the gene what will happen to his daughters?

About the brca-1 gene (breast cancer gene)...If a male is a carrier for the gene what will happen to his daughters?

50:50 inheritance: Any child of a brca carrier has a 50:50 chance of inheriting that mutation. If they have inherited the mutation, they have a 50-80% chance of developing breast cancer, and an increeased risk of several other cancers. For more information, check this link: http://www.Cancer.Gov/cancertopics/factsheet/risk/brca. ...Read more

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34yr old sister had a brca test done.Her results came back as positive for one copy of c.6937+594t> g mutation in brca 2 gene.What does this mean?

? deleterious, now U: The testing report should specify if this is a "deleterious" mutation. If it is, then it is present throughout all her breast tissue increasing her risk of a second/subsequent breast cancer. It also confers a significant risk of ovarian cancer. As a 1st degree relative, you would have a 50% chance of carrying the same mutation and should be tested for this specific mutation. ...Read more

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No one on family has any type of cancer except one great aunt breast cancer @ 71 I am Ashkenazic Jew should I get brca test?

No one on family has any type of cancer except one great aunt breast cancer @ 71 I am Ashkenazic Jew should I get brca test?

What will do with: the result? Given your family history, you are not likely to have BRCA gene. However, before getting tested, you need to ask yourself, what will you do with the results? Will you get bilateral mastectomy if it is positive? For good health - Have a diet rich in fresh vegetables, fruits, whole grains, low fat milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form. Practice safe sex. ...Read more