Top
30
Doctor insights on: What Does Benign Follicular Thyroid Cells Mean

Share
Dr. Jan Lei Iwata
13 Doctors shared insights

Thyroid (Definition)

The thyroid is an endocrine gland that sits in the lower part of the neck. It produces thyroid hormone - which ...Read more


2

2
What does benign follicular cells in mixed micro macrofollicular pattern, focal hurthle cell changes histiocytes mean? 3cm nodule on thyroid fast grow

What does benign follicular cells in mixed micro macrofollicular pattern, focal hurthle cell changes histiocytes mean? 3cm nodule on thyroid fast grow

Discuss: For a 3 CM fast growing thyroid mass, there is a higher chance of false negative with the biopsy. Not all the mass could be cancerous and the cancer spot could have been missed during fna because the mass is big at 3 cm. Most prudent step now is to follow for size changes and rebiopsy if it changes in 1 year. Depending on your age and current compressive symptoms, surgery is an option. ...Read more

3

3
Thyroid biopsy cold nodule showed Follicular cells 2x4cm. Being sent out for generic testing? Will this show if it's benign?

Thyroid nodules: This is a good question and not totally resolved in the thyroid cancer field. On needle aspiration, it is often impossible to distinguish between a follicular adenoma (benign) or follicular cancer. The genetic tests theoretically help make the distinction. But they are not perfect. Many doctors would send you to a good thyroid surgeon and remove a 2x4 cm thyroid nodule with follicular cells. ...Read more

4

4
Please would like to know what is meant by thyroid shows well defined follicular neoplasm composed of cells with granular cyloplasm, is it cancer?

Please would like to know what is meant by thyroid shows well defined follicular neoplasm composed of cells with granular cyloplasm, is it cancer?

Need to discuss: With your doctor/endocrinologist. Need more information such as clinical picture, ultrasound results, lab tests etc. This is too important to get diagnosed over the internet. ...Read more

5

5
My thyroid biopsy results shows a benign follicular nodule with colloid, blood and few hurthle cells. Should I be concerned with the hurthle cells?

My thyroid biopsy results shows a benign follicular nodule with colloid, blood and few hurthle cells. Should I be concerned with the hurthle cells?

Cautious yes: Hurtle (Hurthle) cell neoplasia (HCN) seen in both in benign adenoma and malignant. In your case is in a benign follicular adenoma, due their erratic behavior most will treat them aggressively by removal. Speak to your doctor. ...Read more

6

6
Two nodules, 1.9 and 1.8 CM on left thyroid lobe. 1st nodule is benign follicular. 2nd is abundant benign appearing follicular epithelial cells, hemosiderin-laden macrophages & colloid noted. Cancer?

Not cancer: Both nodules sound perfectly benign by their histologic description. Sonographic (ultrasound) follow-up is recommended in 12 months to ensure stability. ...Read more

8

8
What is rare histiocytes and follicular cells in thyroid nodule?

What is rare histiocytes and follicular cells in thyroid nodule?

Incomplete informat: The presence of histiocytes (a type of inflammatory cell) & expected follicular cells in thyroid is not necessarily worrisome. But it depends on your symptoms, & what prompted the biopsy / FNA to begin with. Also, did you have a radioactive iodine exam? (Called "thyroid uptake & scan")? That tells you if the follicle is "functional" or not (making hormone). A hyperfunctional nodule is more worriso ...Read more

9

9
Cn thyroid scan diffrentiate between benign n malignant follicular neoplsm?

Cn thyroid scan diffrentiate between benign n malignant follicular neoplsm?

NO: Hi. Nope, you need tissue (cells). Either an FNA for cytology (which may be non-diagnostic) or a surgical biopsy. Scan adds nothing to the diagnostic evaluation ...Read more

10

10
If follicular epithelial cells are present is surgery to remove the thyroid necessary?

If follicular epithelial cells are present is surgery to remove the thyroid necessary?

Follicular lesion: I assume you had a needle biopsy that identified follicular cells and your doctor is recommending removal of that lobe. A needle biopsy is not able to differentiate between a benign or malignant follicular tumor so surgery is the usual recommendation to clarify that situation. ...Read more

12

12
Does mild intrinsic vascularity mean anything on a solid micro follicular thyroid lesion which is circumscribed and heterogeneous?

Does mild intrinsic vascularity mean anything on a solid micro follicular thyroid lesion which is circumscribed and heterogeneous?

Possibly: I want to clarify your description. You wrote a micro follicular lesion. This is an older pathology dx. Was this biopsied or is this a micronodule (<1 cm). Well circumscribed is good. Heterogeneous nod need to know the character of the solid part. After the other info, increased blood flow is a risk factor cancer (but now considered a minor factor). Thyroid func is key here. W/more info FNA or not ...Read more

13

13
What exactly does the terms circumscribed and heterogeneous actually mean relating to a solid thyroid micro follicular lesion. Flus on biopsy.?

What exactly does the terms circumscribed and heterogeneous actually mean relating to a solid thyroid micro follicular lesion. Flus on biopsy.?

Good signs: Circumscribed lesion on thyroid ultrasound means that the lesson is encapsulated and that this is a good sign. Heterogenous mean that the lesion has various areas of increased and decreased density and that is also a good sign. However follicular lesions are indeterminant and could be malignant. ...Read more

14

14
Thyroid follicular lesion 2.4cm solid circumscribed with mild vascularity. Thyroseq pending Can this test show a definite benign? What's circumscribed

Thyroid follicular lesion 2.4cm solid circumscribed with mild vascularity. Thyroseq pending Can this test show a definite benign? What's circumscribed

Need FNA: Only biopsy will give definitive answer, it it is benign or malignant. Most likely your doctor will recommend fine needle aspiration (FNA) biopsy a simple out patient procedure Follow the advise of your doctor. ...Read more

15

15
1st FNA is benign follicular lesion, u/s ;hypoechoic thyroid nodule with few small calcifications, 2nd FNA ; hard consistency solid nodule, %ofcancer?

1st FNA is benign follicular lesion, u/s ;hypoechoic thyroid nodule with few small calcifications, 2nd FNA ; hard consistency solid nodule, %ofcancer?

Talk to YOUR MD: You clearly have a thyroid problem, and this needs to be discussed in context of the bigger clinical picture. If you have had FNA done, you have a doc following you. See them and ask what this means in your case and what should be done next. Lab results never occur in isolation. They occur in people, and the whole person has to be considered when making a diagnosis and treatment plan. Best wishes! ...Read more

16

16
Thyroid fnac report-atypia of undetermined significance or follicular neoplasm. What it means? Treatment?

Thyroid FNA: Hi. A follicular neoplasm of undetermined significance means the cytology doesn't meet criteria for cancer or benign, thus the "undetermined significance". Historically, most of these turn out to be benign, but a significant subset are cancer. It appears they did not do gene testing. Next step would usually be surgical excision of the nodule, frozen section analysis, then total thyroidectomy if CA ...Read more

17

17
Thyroid show small round evenly spaced nuclei rare group of follicular cells midly enlarged overlapping nuclei with pale chromatin?

What is the question: I assume you mean the pathology report from a thyroid biopsy. If so, it needs to be discussed in detail (along with the other clinical information) with your doctor who is delivering your care, not someone on the internet, ...Read more

18

18
Thyroid biopsy was colloid only no follicular cells rad. Suggests another biopsy dr recommends seeing a surgeron dr said another biopsy would be same

Thyroid biopsy was colloid only no follicular cells rad. Suggests another biopsy dr recommends seeing a surgeron dr said another biopsy would be same

No short answer: Seeing just colloid and no follicular cells on a thyroid biopsy usually means that the nodule was mostly cystic so that thyroid tissue was not removed. A repeat biopsy by an experienced physician directed at getting thyroid tissue and not fluid could be helpful. Most people in your age group do not need surgery for this biopsy result, but rather, periodic ultrasound to look for significant chang. ...Read more

19

19
Can a "normal" thyroid nodule develop abnormal follicular neoplasm cells over time?

Possibly: Ghe tendency for transformation of a nodule in the thyroid gland depends on whether the nodule is solitary or multiple. The latter for the most part is a goiter and rarely if ever associated with Ca of thyroid. A solitary nodule has to be examined as to being hot or cold. If hot and functional Ca essentially doesn't occur. If the solitary nodule cold, there is a 30% chance of converting to Ca. ...Read more

20

20
Fnac report of thyroid nodule-colloid, individual follicular cell n folliculr cell in cluster in haemorrhagic bckground. What it indicate?

Nothing: Reports states the nodule was benign which means not cancerous, hemorrhagic, there was some blood which was probably from the size of needle used so don't worry. ...Read more

21

21
I have bilateral partially cystic thyroid nodules. Biopsy done of the larger one, came back "follicular lesion of unknown origin" what does that mean?

Variable meaning: Follicularā€patterned lesions of the thyroid are common; these include hyperplastic/adenomatoid nodules, follicular adenoma, follicular carcinoma and follicular variants of papillary carcinoma. Repeat biopsy with a sample sent for a genetic afirma assay may give additional useful information. In addition, discuss with your endocrinologist. ...Read more

22

22
A fna on a thyroid nodule came back as "follicular lesion of undetermined significance". What does that mean and what happens next?

A fna on a thyroid nodule came back as "follicular lesion of undetermined significance". What does that mean and what happens next?

Thyroid tumors: In hyperthyroidism are rare. If the index of suspicion is low, repeat sonogram in a few. Omths, ofherwise proceed with an open biopsy. Make sure you are nit taking too much merhimazole. ...Read more

23

23
What do these biopsy results of thyroid nodule mean ATYPIA OF UNDETERMINED SIGNIFICANCE OR FOLLICULAR LESION OF UNDETERMINED SIGNIFICANCE?

Re-FNA in 3-6 Months: Hi Jami, AUS/FLUS is a term that cytopathologists use for thyroid nodules that they basically are "unsure" about. Classic management for this diagnosis is to have a second repeat FNA in 3-6months. Nowadays though high tech molecular pathology tests can sometimes divide AUS/FLUS definitively into benign and malignant categories. Please setup a virtual consult with me for more information. ...Read more

24

24
Fna thyroid cytology report said the specimen quantity is insufficient for cellblock w/follicular nodulal goiter. What does this mean?

Fna thyroid cytology report said the specimen quantity is insufficient for cellblock w/follicular nodulal goiter. What does this mean?

Non-diagnostic: Generally means the test is non-diagnostic. I suggest repeating the FNA. Please find an experienced radiologist who can do the FNA under ultrasound guidance. ...Read more

25

25
My thyroid nodule fna came back as "benign follicularadenoma." I thought follicular growths had to be examinedthrough surgery. Are these results accurate?

Gray area: Thyroid fna can be difficult for a pathologist, on the limited sample, to be confident that the nodule is benign. For that reason, the pathology report may leave open the possibility that it is either benign or malignant. There is no absolute right or wrong, and it can depend on the experience and decisiveness of the examining pathologist. ...Read more

26

26
32 years old male. Thyroid Bilateral Multiple nodule, The largest size is 1.5*1.78*0.839 cm. Three times FNA. Result is No EVIDENCE OF MALIGANCY. Comment: Follicular cell, Hurthle cell and colloid are seen. I worry about the Hurthle cell. My Surgeons only

32 years old male. Thyroid Bilateral Multiple nodule, The largest size is 1.5*1.78*0.839 cm. Three times FNA. Result is No EVIDENCE OF MALIGANCY. Comment: Follicular cell, Hurthle cell and colloid are seen. I worry about the Hurthle cell. My Surgeons only

Thyroid nodules: Usually we worry about a solitary nodule in a male and it appears that you are in good hands and the biopsies are reassuring. For further reassurance we depend on a combination of an endocrinologist or thyroidologist and a surgeon skilled in thyroid surgery reviewing your findings and I would be quite comfortable with their advice and follow-up. ...Read more

27

27
Left thyroid papillary carcinoma. Some follicular cells show hurthle cell/oncocytic changes. Is the treatment generally thyroidectomy & rad. Iodine?

Size matters: Depending on size and charevteristics most would recommend a total thyroid and possible radioactive iodine. Speak to your surgeon and endocrinologist. ...Read more

28

28
1 CM solid node l thyroid lobe a mixed micro and macro- follicular lesion fna consists of follicular cells in small follicles microfollicles & small sheets displaying extensive hurthle cell changes?

1 CM solid node l thyroid lobe a mixed micro and macro- follicular lesion fna consists of follicular cells in small follicles microfollicles & small sheets displaying extensive hurthle cell changes?

Now benign: From your information it isa benign adenoma, hurthle cell are little larger pinkish cell, but have higher incidence of malignant transformation than follicular, to hurthle cell carcinoma, unlike follicular, it will spread to lung, bone etc, follow your doctor's advice. ...Read more

29

29
I was told I had a benign follicular adenoma after a fna on my thyroid nodule. Ā is it possible to know this without surgery?

Cytology: Looking at a cellular aspirate is the first line test for evaluating a thyroid nodule. It should be collected under ultrasound guidance to ensure the sample is from the nodule. The accuracy is 90%. If there are doubts, the sample slides can be reviewed by a reference expert cytologist. Additionally, molecular testing can be done on material obtained at biopsy or on the pathology slides. ...Read more

30

30
Fna on thyroid nodule shows predominately hurthle cells with follicular and colloid....34yrs old....nodule 2.7cm...hurthle cells cancer??

Fna on thyroid nodule shows predominately hurthle cells with follicular and colloid....34yrs old....nodule 2.7cm...hurthle cells cancer??

Hurtle cell: Hurtle cell cancer is very uncommon but does occur in some patients.
The thyroid nodule of 2.7 cm requires attention and may need biopsy. Please discuss this with your doctor. ...Read more