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Doctor insights on: What Does An Inflammation Marker Mean

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Inflammation (Definition)

Inflammation is the body's attempt at self-protection; the aim being to remove harmful stimuli, including damaged cells, irritants, or pathogens - and begin the healing process. Inflammation is part of the complex biological response of vascular tissues to harmful stimuli, such as pathogens, ...Read more


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What does it mean if a 6 y/o child has elevated white blood cell count and his inflammation marker is high?

What does it mean if a 6 y/o child has elevated white blood cell count and his inflammation marker is high?

Viral vs bacterial: Not too infrequently, children present with fever without clear source. We have utilized white cell count and inflammation markers, e.g., sed rate or CRP to distinguish viral vs bacterial infection. Elevated white blood cell and high inflammation marker suggest the likelihood of bacterial infection. ...Read more

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What could be wrong if my inflammation markers are high. I've had like 3 different sets of blood work done & they've been high each time.

What could be wrong if my inflammation markers are high. I've had like 3 different sets of blood work done & they've been high each time.

Injury, infection & : Your body can get inflamed due to injury, infection and/or allergies. Inflammatory markers tell us there's a needle in the haystack but they don't tell us where. So it's our job to question you regarding the possible causes. If you can't think of any, then we worry about an increase risk of heart disease. But since you're young, ask your doc why s/he ordered them in first place. Could be just gum. ...Read more

Dr. Alvin Lin Dr. Lin
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What are the new tests to check for inflammation in the body, the new inflammatory markers ?

Dr. Alvin Lin Dr. Lin
1 doctor agreed:

How new is new?: Check out BMJ from 2/3/12 doi: http://dx.doi.org/10.1136/bmj.e454 "Inflammatory markers include C reactive protein (CRP), erythrocyte sedimentation rate, plasma viscosity, fibrinogen, ferritin, and several other acute phase proteins, though only the first three are commonly referred to as inflammatory markers". ...Read more

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Why can bronchial inflammation come with elevated d dimer marker?

Why can bronchial inflammation come with elevated d dimer marker?

Not always: Elevated. D dimer has many reasons. Severe. Sepsis. Infections. Malignancy. Thromboembolic disease. So. If there is severe inflammation it can raise it . Negative. D. Dimer is used to. Rule out thromboembolic disease. Being positive could have any nonspecific reason. ...Read more

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Which is a better marker to use for inflammation in body ESR or crp? Have high ESR but normal CRP i'm so confused been diagnosed with temporarteritis

Which is a better marker to use for inflammation in body ESR or crp? Have high ESR but normal CRP i'm so confused been diagnosed with temporarteritis

Difficult: CRP is to some extent more elevated when the inflammatory condition is due to infection. The ESR usually goes up with any inflammation that effects the endovascular endothelium (inside walls of blood vessels). It is classically over 100 in patients with temporal arteritis. Hope you are being treated aggressively with steroids. Get better. ...Read more

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I have cd, in remission, with a calprotectin level under 16. My dr. Now suggests a s.B. Mri. Is this not a good marker for inflammation in s.B as well?

I have cd, in remission, with a calprotectin level under 16. My dr. Now suggests a s.B. Mri. Is this not a good marker for inflammation in s.B as well?

Small bowel MRI: Is superior to ct of the small bowel. Mri shows tissues and tissue contrast better than ct. It shows enhancement better. It is safer. The contrast used for MRI is safer than ct contrast. Ct uses a lot of radiation. Mri uses no ionizing radiation. Adding special sb images is quick and easy. And overall the MRI study can tell us more information than the ct exam. ...Read more

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Can you still have inflammation with normal CRP and sed rate titers ? And what are the best markers for inflammation ?

Can you still have inflammation with normal CRP and sed rate titers ? And what are the best markers for inflammation ?

It depends on....: It depends on the severity of inflammation that is present. If you're talking about the type of inflammation that you might see from an insect bite or a dog scratch then sed rate and CRP will often be normal. If you're talking about the type of inflammation that can occur with a major pneumonia or severe infection of the kidney then typically both would be high. The CRP is more sensitive of the 2 ...Read more

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Why might methotrexate be greatly controlling symptoms in udct when all inflammatory markers have been nearly normal? Ana 1:640. Hidden inflammation?

Why might methotrexate be greatly controlling symptoms in udct when all inflammatory markers have been nearly normal? Ana 1:640. Hidden inflammation?

See details: I do not understand your question. If the markers of inflammation are normal and you are doing well, what more do you want? The ANA does not relate to disease activity so do not pay much attention to it. ...Read more

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Excised lymph node mis. pos. markers: cd45=100, cd38=73, FMC7=7. DR only said inflammation. Can these results guide as to what kind of inflammation?

Excised lymph node mis. pos. markers: cd45=100, cd38=73, FMC7=7. DR only said inflammation. Can these results guide as to what kind of inflammation?

No: These results cannot guide as to what caused the inflammation. The most common cause would be from a past or current viral infection leaving you with a reactive lymph node. Other causes could be a past or current bacterial or fungal infection, from autoimmune disease, and from drugs or medication. It sounds like your doc is saying that it isn't from cancer and other misc diseases like sarcoidosis. ...Read more

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Positive Ana, low ck, high inflammation markers with extreme leg pain but no other abnormalities. Please help me look in the right direction. ?

Positive Ana, low ck, high inflammation markers with extreme leg pain but no other abnormalities. Please help me look in the right direction. ?

Insufficient info: First I wish you relief, but given the above, you need to start with your own doctor, which you probably had, as you have some lab results, or go to the ER to rule out some serious conditions as venous thrombosis, ischemia or any vascular problem, then look for the other conditions that cause this picture, physical exam and thorough history are needed, good luck ...Read more

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Is the test for HLA-B27 gene a simple YES/NO? Remember my rheumatologist saying "highly elevated". Perhaps inflammation markers or referring to gene?

Is the test for HLA-B27 gene a simple YES/NO? Remember my rheumatologist saying "highly elevated". Perhaps inflammation markers or referring to gene?

Yes/no: HLA-B27 is a genetic test and the result should be yes or no. You are correct about inflammatory mediators, such as sed rate or C-reactive protein which are measured as a quantity and would be high with active inflammation. ...Read more

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What exactly does it mean if I have inflammation in my blood?

What exactly does it mean if I have inflammation in my blood?

Usually...: Infection, arthritis, or other autoimmune inflammation! the best marker is the CRP test. But it can be elevated in certain metabolic conditions such as type 2 diabetes, which has a strong systemic inflammatory component. ...Read more

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I feel okay but my CRP levels were high and apparently that means inflammation?

Forget about it: Many people run a high CRP for no reason. It may be genetic, and hopefully you know that the reference ranges are set so that several % of healthy folks fall outside. As a lab specialist, I don't even think folks should be screened -- but in today's medicine, physicians may need to "cover their butts" with this kind of unnecessary testing. Get on with your life. ...Read more

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Bloodtest. Said inflammation very high what does that mean?

Inflammatory markers: Very high in this case could mean infection, rheumatologic, and malignancy. Hope its none of these and would need to know which exact marker, other lab results, and your symptoms if any. ...Read more

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What does this mean? reactive cellular changes associated with inflammation

What does this mean? reactive cellular changes associated with inflammation

Immune response: It just means there is evidence of an immune system response. Without further details it's not possible to speculate more about the cause. ...Read more

Marker (Definition)

A "marker" is a protein or enzyme that can represent a disease process. Some markers are specific for a particular disease, while ...Read more