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What Does An Ana Genetic Marker Mean
From a medical standpoint, "genetic" refers to the potential heritability of various medical conditions. While some conditions are inevitable (at some point in one's life) as a consequence of simple genetic heritability (eg huntington's disease), a large number of medical conditions (including all behaviorial health disorders) are the expressed final pathway of a ...Read more
AM 19 having recurrent acute pancreatitis idiopathic and doc said to do ANA profile. Test and genetic mutations test WILL THEY HELP.
Yes: Hereditary pancreatitis occurs as a mutation in a gene on chromosome 7. It will require follow up and family checking if found. Recurrent pancreatitis can also be autoimmune and also be associated with autoimmune diseases and finding one would influence management. Very important to do at your age. ...Read more
Is the mere fact that my ANA is 1:640 & I get bad flares mean my body is attacking itself? My inflammatory markers are neg. I am being treated w/ meds.
Ana marker of 1.32 what does it mean, I have had it checked twice over the past 3 months and it has stayed the same. No symptoms excepts crampy hands?
Possibly nothing: This is a low concentration of ANA and oftentimes has no clinical meaning. It really ddepends on what symptoms and other findings there are. Crampyness in the hands is not usually related to any of the dieases associated with a positive ana. Often, it may take long peiords of time for other symprtoms to develop. Need to keep watch. ...Read moreSee 1 more doctor answer
What does it mean to have 3 out of 6 genetics markers when getting test results as a kidney donor?
Variable: Hla antigens are a major factor that drives the rejection response to transplant organs. Matching refers to the number of hla antigens identified in recipients and donors; and how many are the same. Commonly six antigens; two for hla a, two for hla b, and two for hla dr are typed matched for kidney transplant. So a 3/6 match means half the hla antigens are the same. ...Read moreSee 1 more doctor answer
What does it mean to have 3/6 genetics markers when getting test results for being a kidney donor?
That u r a 1/2 match: We each inherit one set of three human leukocyte antigens (hla) from each parent; thus, we each have 6 of these. The more hla matching between donor and recipient of the kidney, the closer the match, the less likely is rejection and less anti-rejection drugs need be used. The best match is 6/6, the worst is 0/6. A half match is 3/6 genetic markers=possible donor. Transplant team will decide. ...Read more
Can a positive ANA (going up for years, now 1/640) be insignificant if other autoimmune markers are negative?
Probably not: If you don't have symptoms but why are they checking it?? Ask the person who ordered it to be sure. They know you and your history. ...Read more
My ANA was positive but no other markers of autoimmune disease were found. Also non specific elevateKappa free light chain which is also non specific.
Non-diagnostic: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, the findings you described are not diagnostic of any illness. These and any other test results need to be evaluated in the context of your symptoms and findings on physical examination. For good health - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Drink enough water daily, so that your urine is mostly colorless. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form. Practice safe sex. ...Read more
Can someone explain 2 me how I can feel terrible with lupus even when my inflammatory markers & other labs (other than high ana) are currenlty normal?
What is the gold standard test for sjorgens. Had high ana's in the past and then they were ok, then high, Inflammatory markers usually normal.?
Antibody and dryness: Diagnosis of Sjogrens requires more than one condition to be satisfied. One being antibody markers and the other being dryness of eyes and mucus membranes. You may consult this site for more info: http://www. Mayoclinic. Org/diseases-conditions/sjogrens-syndrome/basics/tests-diagnosis/con-20020275 Wish you good health! ...Read more
What is the likelihood that lupus or sjogrens is causing lbs like and autoimmune symptoms? Chrons has been ruled out. Low pos ANA and sjogrens markers
Should my identical twin sister be tested for DNA because I have inflammatory markers and postive ANA antibody test?
It's her call: It sounds like a search for lupus. If you do turn out to have lupus, it's way below even-money that your identical twin will ever be affected, there's little to be gained from early diagnosis, if she develops symptoms she has the heads-up. The antibodies do appear several years before the illness if she is very curious. ...Read moreSee 1 more doctor answer
Why might all inflammatory markers be negative during lupus flare? I do have consistent ANA of 1:640 though. Prednisone helps my recurring flares.
ANA: no correlation!: There is no correlation with ANA titer and lupus flares! There is with anti-dna antibodies, and various other tests including c2, c4, lymphocyte count. Sle does not raise CRP for unknown reasons! Discuss this rheumatology issue with your rheumatologist or pcp. Irrespective of Prednisone helping flares, you should be on plaquenyl which prevents flares! ...Read more
Ana positive 160 poss mtcd w/o lupus markers. What can cause 300 mg/dL lambda 200 lambda if no paraprotein? Check igd/e? Urine spot lambda bjp found
BJP: Bence Jones proteins, light chain, occur in multiple myeloma, lymphomas/chronic leukemias, monoclonal gammopathy of undetermined significance which can go on to myeloma at the rate of only 1%/yr -small risk), amylodosis, cryoglobunemia, Autoimmune disease can give false positive. Check IFE & bone marrow http://www. Livestrong. Com/article/372234-about-multiple-myeloma-and-bence-jones-protein/ ...Read more
Are fevers common in pots? Been getting almost daily low fevers of 99.5-100.5 for 6 weeks. Wbc, ANA and inflammatory markers normal. Doc has no idea if normal for pots.
I had ANA 1:160+, ESR 29 CRP 0.1 autoantibodies show ssa of 8 (0-40 is neg) and scl-70 ENA ab of 3 (0-40 is neg) wouldn't this be scleroderma? Not lupus? Why would lupus patient have scl-70 markers?
Not just antibodies: If the scl-70 titer is 3, as you wrote, it falls within the normal range and is not positive. More importantly, scleroderma is not diagnosed on the basis of antibody studies, but rather clinical findings such as skin thickening, raynaud's phenomenon, lung fibrosis, or pulmonary hypertension. A certain percentage of scleroderma patients are even negative for ana. ...Read moreSee 1 more doctor answer
See details: The titer is more important than the pattern. Without knowing the symptoms that led to the test being ordered, it is impossible to answer your question. ...Read more
An "ana" is a blood test used to screen a person for the possibility of several autoimmune diseases. It is important to remember that this is a screening test and a positive result only indicates more testing may be warranted. No blood test is perfect, and getting to a diagnosis is usually much more complex than drawing blood and looking at a number ...Read more
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