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Doctor insights on: What Does A Positive Lupus Anticoagulant Test Mean During Pregnancy

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I tested weakly positive for lupus anticoagulant. I have been on baby aspirin for 2months now, can I have a successful pregnancy on that alone?

I tested weakly positive for lupus anticoagulant. I have been on baby aspirin for 2months now, can I have a successful pregnancy on that alone?

See details: A low positive test is not clinically significant so no preventative therapy is needed. There is no evidence that low dose ASA has any value in this situation. ...Read more

Dr. Boris Aronzon
523 doctors shared insights

Blood Thinners (Definition)

Agents which slow ;/or break down blood clot formation in up to 3 different ways (they do not decrease blood viscosity; thickness.) (1) some inhibit platelet function (e.g. Aspirin, clopidogrel, etc.). (2) others interfere with some of the clot forming proteins (warfarin, dabigatran, rivaroxaban, etc.), (3) others stimulate the blood clot destruction ...Read more


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I have been having recurrent miscarriages.I tested weakly positive for lupus anticoagulant. Can I have a successful pregnancy on baby aspirin?

No: Low dose Aspirin is not an effective therapy for this issue. You need to be on subcutaneous heparin. See a rheumatologist or hematologist for appropriate treatment. ...Read more

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Is it sle or lupus anticoagulant that causes pregnancy problems?

Is it sle or lupus anticoagulant that causes pregnancy problems?

Lupus and pregnanacy: Sle or lupus is less likely to cause serious problems in pregnanacy if the disease is well controlled before conception, especially if you are cared for by both a rheumatologist and "high risk" ob. Also presence of lupus anticoagulant can be managed suceesfully. ...Read more

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Hi Dr,I did lupus anticoagulant test.it shows appt(test)-ls 41.7 observed value.lupus anticoagulant absent means?I have recurrent two abortion

Hi Dr,I did lupus anticoagulant test.it shows appt(test)-ls 41.7 observed value.lupus anticoagulant absent means?I have recurrent two abortion

Lupus anti coag: Hello ~ people who have recurrent blood clots to the limbs can in some cases be lupus anti-coagulant positive as a cause and there is increased incidence of natural abortion or miscarriage in those cases. You are lupus anticoagulant negative so its irrelevant as a cause to any clotting disorder. thanks ...Read more

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Had a lupus anticoagulant test done all was normal except for a high thrombin time at 22.8 is this serious? Factor 5 also runs in my family.

Had a lupus anticoagulant test done all was normal except for a high thrombin time at 22.8 is this serious? Factor 5 also runs in my family.

Normally: a factor V deficiency can cause a prolonged thrombin time But your bleeding time and platelet count should be unaffected. Certain medications and other diseases could also cause elevated thrombin time. ...Read more

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Can you explain what a positive test for lupus anticoagulant means?

Can you explain what a positive test for lupus anticoagulant means?

Autoantibodies.: Your body is producing antibodies directed against its own tissues and is likely at increased risk for the development of an autoimmune disease such as lupus erythematosus, rheumatoid arthritis, thyroiditis, vitiligo, infammatory bowel dis or pernicious anemia from gastritis. Lac can cause clotting disorders and miscariages, but is not in and of itself an important predictor of clinical outcomes. ...Read more

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What is the significance of a positive test for lupus anticoagulant?

Blood clots: You are paradoxically at increased risk of having blood clots. Discuss with your doctor. ...Read more

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What do these mean? lupus anticoagulant weakly present at 1.30; positive ANA Test 1:40 speckled pattern; negative anticardioliptin and beta2

What do these mean? lupus anticoagulant weakly present at 1.30; positive ANA Test 1:40 speckled pattern; negative anticardioliptin and beta2

Not much: A weakly present lupus anticoagulant and an ANA of 1:40 are common in the general population, and usually not an indication of an autoimmune disorder. You should visit with the physician who ordered these tests to review them with you however. A test alone does not give any answers. Doctors will need both a patient's history and tests to determine further management. ...Read more

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In 11/2014 I was hospitalized with bilateral PE. 3 lupus anticoagulant tests have come back positive, and he said it's primary. Does that mean APS?

In 11/2014 I was hospitalized with bilateral PE.  3 lupus anticoagulant tests have come back positive, and he said it's primary.  Does that mean APS?

Almost...: In my experience it can be primary, but other autoimmune disease must be excluded. IgM, followed by IgG anti -cardiolipin antibodies are the most problematic! This is important, since apart from anticoagulants, other drugs may be needed. ...Read more

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Can all people diagnosed with the disease lupus test positive to lupus anticoagulant as well?

Not necessarily: This can be seen in the setting of lupus but with other autoimmune diseases as well as some patients can positive for it and not have any associated diseases with it. ...Read more

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I have a positive ana, positive lupus anticoagulant, 386 value for microsomal antibodies. C3 of 113, C4 of 53. A rash on face could it be lupus?

I have a positive ana, positive lupus anticoagulant, 386 value for microsomal antibodies. C3 of 113, C4 of 53.  A rash on face could it be lupus?

Yes: If the rash fits the butterfly or discoid rash or the subacute lupus skin lesion. ANA titer is usually high in lupus; you have not listed yours. The c3 and c4 are markers of disease activity and famously nonspecific. Don't try to self-diagnose; your age of 54 is a bit high for new-onset lupus though it's not impossible. ...Read more

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I was recently tested for lupus anticoagulant and it was postitive. Does that mean I have lupus?

No: Having a "lupus anticoagulant" just means there is an abnormality in your clotting mechanism that may make you m, ore easily bleed and, conversely slightly more likely to clot. While this feature may be seen in the disease lupus it does not mean that everyone with this factor has the disease lupus/ there are msany other features of the disease to look for. ...Read more

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What does a diagnosis of purpura fulmicans and lupus anticoagulant w/possible phophosilid syndrome mean?

What does a diagnosis of purpura fulmicans and lupus anticoagulant w/possible phophosilid syndrome mean?

Complicated question: Complicated question. Depends on severity, comlications and treatment. See rheumatologist. ...Read more

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Can blood work result in a false positive result for lupus anticoagulant factor?

No: Positive is positive. However, it is the degree of positivity that is clinically important. Low positive values are generally not clinically important. ...Read more

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Pt/inr normal, ptt, activated is 3 seconds prolonged, and in the lupus anticoagulant panel, only abnormality is aptt at 41.4 sec. What does this mean?

Any symptoms?: Why were these tests done? Do you have any symptoms? All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. A slightly prolonged PTT in isolation is not a cause for concern, but it would be important to know why your doctor ordered the tests. Lupus is one of the causes of prolonged ptt. ...Read more

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Is aps possible if beta-2 glycoprotein , lupus anticoagulant and cardiolipin-ig-(g/m/a)are >0.2. Is test to be repeated in 1-2yrs if once negative?

Is aps possible if beta-2 glycoprotein , lupus anticoagulant and cardiolipin-ig-(g/m/a)are >0.2. Is test to be repeated in 1-2yrs if once negative?

No: It is highly unlikely that you have apa syndrome if the tests are negative. The test values can vary from time to time and may even be negative on rare occasions. However, if you have symptoms and the tests are negative at that time then you need to find another cause. ...Read more

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I recently had the test for lupus anticoagulant and it was postitive. What are the implications of this?

Depends on history: This test should always be confirmed by repeat and other related tests a prior history of multiple late pregnancy losses and /or unexplained clots make the test more ominous. ...Read more

Dr. Suzanne Galli
4 doctors shared insights

Pregnancy (Definition)

When your due date arrives, you will be more than ready to have your baby! Most women deliver the baby somewhere between 37 and 42 weeks. According to the American College of Obstetricians and Gynecologists, only 5% of babies arrive on the exact due date. Approximately 7% of babies are not delivered by 42 weeks, and when that happens, it is referred to ...Read more


Anticoagulant (Definition)

Anticoagulants are any of a variety of drugs which decrease the body's ability to make or sustain blood clots. They fall, generally, into two categories. Drugs like Aspirin and clopidogrel (plavix) prevent platelets from forming the initial stages of a clot. Drugs like warfarin (coumadin) and dabigatran (pradaxa) block the later process ...Read more