Top
10
Doctor insights on: What Does A Positive Lupus Anticoagulant Test Mean

Share
1

1
Hi Dr,I did lupus anticoagulant test.it shows appt(test)-ls 41.7 observed value.lupus anticoagulant absent means?I have recurrent two abortion

Hi Dr,I did lupus anticoagulant test.it shows appt(test)-ls 41.7 observed value.lupus anticoagulant absent means?I have recurrent two abortion

Lupus anti coag: Hello ~ people who have recurrent blood clots to the limbs can in some cases be lupus anti-coagulant positive as a cause and there is increased incidence of natural abortion or miscarriage in those cases. You are lupus anticoagulant negative so its irrelevant as a cause to any clotting disorder. thanks ...Read more

Dr. Boris Aronzon
504 doctors shared insights

Blood Thinners (Definition)

Agents which slow ;/or break down blood clot formation in up to 3 different ways (they do not decrease blood viscosity; thickness.) (1) some inhibit platelet function (e.g. Aspirin, clopidogrel, etc.). (2) others interfere with some of the clot forming proteins (warfarin, dabigatran, rivaroxaban, etc.), (3) others stimulate the blood clot destruction ...Read more


2

2
Had a lupus anticoagulant test done all was normal except for a high thrombin time at 22.8 is this serious? Factor 5 also runs in my family.

Had a lupus anticoagulant test done all was normal except for a high thrombin time at 22.8 is this serious? Factor 5 also runs in my family.

Normally: a factor V deficiency can cause a prolonged thrombin time But your bleeding time and platelet count should be unaffected. Certain medications and other diseases could also cause elevated thrombin time. ...Read more

See 2 more doctor answers
3

3
Can you explain what a positive test for lupus anticoagulant means?

Can you explain what a positive test for lupus anticoagulant means?

Autoantibodies.: Your body is producing antibodies directed against its own tissues and is likely at increased risk for the development of an autoimmune disease such as lupus erythematosus, rheumatoid arthritis, thyroiditis, vitiligo, infammatory bowel dis or pernicious anemia from gastritis. Lac can cause clotting disorders and miscariages, but is not in and of itself an important predictor of clinical outcomes. ...Read more

4

4
What is the significance of a positive test for lupus anticoagulant?

Blood clots: You are paradoxically at increased risk of having blood clots. Discuss with your doctor. ...Read more

See 1 more doctor answer
5

5
In 11/2014 I was hospitalized with bilateral PE. 3 lupus anticoagulant tests have come back positive, and he said it's primary. Does that mean APS?

Almost...: In my experience it can be primary, but other autoimmune disease must be excluded. IgM, followed by IgG anti -cardiolipin antibodies are the most problematic! This is important, since apart from anticoagulants, other drugs may be needed. ...Read more

6

6
What do these mean? lupus anticoagulant weakly present at 1.30; positive ANA Test 1:40 speckled pattern; negative anticardioliptin and beta2

What do these mean? lupus anticoagulant weakly present at 1.30; positive ANA Test 1:40 speckled pattern; negative anticardioliptin and beta2

Not much: A weakly present lupus anticoagulant and an ANA of 1:40 are common in the general population, and usually not an indication of an autoimmune disorder. You should visit with the physician who ordered these tests to review them with you however. A test alone does not give any answers. Doctors will need both a patient's history and tests to determine further management. ...Read more

9

9
Can all people diagnosed with the disease lupus test positive to lupus anticoagulant as well?

Not necessarily: This can be seen in the setting of lupus but with other autoimmune diseases as well as some patients can positive for it and not have any associated diseases with it. ...Read more

10

10
I have a positive ana, positive lupus anticoagulant, 386 value for microsomal antibodies. C3 of 113, C4 of 53. A rash on face could it be lupus?

I have a positive ana, positive lupus anticoagulant, 386 value for microsomal antibodies. C3 of 113, C4 of 53.  A rash on face could it be lupus?

Yes: If the rash fits the butterfly or discoid rash or the subacute lupus skin lesion. ANA titer is usually high in lupus; you have not listed yours. The c3 and c4 are markers of disease activity and famously nonspecific. Don't try to self-diagnose; your age of 54 is a bit high for new-onset lupus though it's not impossible. ...Read more

See 1 more doctor answer

Anticoagulant (Definition)

Anticoagulants are any of a variety of drugs which decrease the body's ability to make or sustain blood clots. They fall, generally, into two categories. Drugs like Aspirin and clopidogrel (plavix) prevent platelets from forming the initial stages of a clot. Drugs like warfarin (coumadin) and dabigatran (pradaxa) block the later process ...Read more


Lupus Anticoagulant (Definition)

If your "lupus anticoagulant" test is positive, it indicates that your blood may clot more easily than it should (long story on the reason for the backwards name). It is important to know that this is only one of several tests for abnormal clotting that a person with an autoimmune ...Read more