Doctor insights on:
What Does A Positive Lupus Anticoagulant Test Mean
Hi Dr, I did lupus anticoagulant test. It shows appt (test)-ls 41.7 observed value. Lupus anticoagulant absent means? I have recurrent two abortion
Lupus anti coag: Hello ~ people who have recurrent blood clots to the limbs can in some cases be lupus anti-coagulant positive as a cause and there is increased incidence of natural abortion or miscarriage in those cases. You are lupus anticoagulant negative so its irrelevant as a cause to any clotting disorder. Thanks ...Read more
Agents which slow ;/or break down blood clot formation in up to 3 different ways (they do not decrease blood viscosity; thickness.) (1) some inhibit platelet function (e.g. Aspirin, clopidogrel, etc.). (2) others interfere with some of the clot forming proteins (warfarin, dabigatran, rivaroxaban, etc.), (3) others stimulate the blood clot destruction ...Read more
Had a lupus anticoagulant test done all was normal except for a high thrombin time at 22.8 is this serious? Factor 5 also runs in my family.
Autoantibodies.: Your body is producing antibodies directed against its own tissues and is likely at increased risk for the development of an autoimmune disease such as lupus erythematosus, rheumatoid arthritis, thyroiditis, vitiligo, infammatory bowel dis or pernicious anemia from gastritis. Lac can cause clotting disorders and miscariages, but is not in and of itself an important predictor of clinical outcomes. ...Read more
Blood clots: You are paradoxically at increased risk of having blood clots. Discuss with your doctor. ...Read more
In 11/2014 I was hospitalized with bilateral PE. 3 lupus anticoagulant tests have come back positive, and he said it's primary. Does that mean APS?
What do these mean? Lupus anticoagulant weakly present at 1.30; positive ANA Test 1:40 speckled pattern; negative anticardioliptin and beta2
Not much: A weakly present lupus anticoagulant and an ANA of 1:40 are common in the general population, and usually not an indication of an autoimmune disorder. You should visit with the physician who ordered these tests to review them with you however. A test alone does not give any answers. Doctors will need both a patient's history and tests to determine further management. ...Read more
No: No and it also occurs in people without lupus. ...Read more
Most, not all.: Lac is common in sle, but not universal. ...Read more
Not necessarily: This can be seen in the setting of lupus but with other autoimmune diseases as well as some patients can positive for it and not have any associated diseases with it. ...Read more
I have a positive ana, positive lupus anticoagulant, 386 value for microsomal antibodies. C3 of 113, C4 of 53. A rash on face could it be lupus?
Yes: If the rash fits the butterfly or discoid rash or the subacute lupus skin lesion. ANA titer is usually high in lupus; you have not listed yours. The C3 and C4 are markers of disease activity and famously nonspecific. Don't try to self-diagnose; your age of 54 is a bit high for new-onset lupus though it's not impossible. ...Read more
I recently had the test for lupus anticoagulant and it was postitive. What are the implications of this?
No: Having a "lupus anticoagulant" just means there is an abnormality in your clotting mechanism that may make you m, ore easily bleed and, conversely slightly more likely to clot. While this feature may be seen in the disease lupus it does not mean that everyone with this factor has the disease lupus/ there are msany other features of the disease to look for. ...Read more
I tested positive for lupus anticoagulant when I was pregnant but do not now. My brother has as and my son is + for hlab27. Should I get tested again?
Different things: The + hal b-27 not related to lupus anticoagulant (la). The la needs to confirmed, especially if you have a history of clinical problems related to the la like blood clots in the legs, emboli to the lung, strokes, misscarriages, etc. Depending on the clinical picture you may need therapy - many only Aspirin for its anticlotting ability or stronger blood thinners. ...Read more
No: Positive is positive. However, it is the degree of positivity that is clinically important. Low positive values are generally not clinically important. ...Read more
Pt/inr normal, ptt, activated is 3 seconds prolonged, and in the lupus anticoagulant panel, only abnormality is aptt at 41.4 sec. What does this mean?
Any symptoms?: Why were these tests done? Do you have any symptoms? All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. A slightly prolonged PTT in isolation is not a cause for concern, but it would be important to know why your doctor ordered the tests. Lupus is one of the causes of prolonged ptt. ...Read more
What does a diagnosis of purpura fulmicans and lupus anticoagulant w/possible phophosilid syndrome mean?
Complicated question: Complicated question. Depends on severity, comlications and treatment. See rheumatologist. ...Read more
Hi I had 2 blood test that came back with lupus anticoagulant in feb 2012. I got told this won't affect me unless I get pregnant again is this true.
Tested for anti cardiolipin IgM is negative (0.7) but IgG is positive (54.8) normal range of lupus anticoagulant, protein S and protein C activity help?
Not sure: I am not sure I understand the question. I suspect you are being evaluated for a blood clotting disorder and you have an elevated anticardiolipin IgG. One test however does not make the diagnosis of anti-phospholipid syndrome. ...Read more
Is aps possible if beta-2 glycoprotein, lupus anticoagulant and cardiolipin-ig- (g/m/a)are >0.2. Is test to be repeated in 1-2yrs if once negative?
No: It is highly unlikely that you have apa syndrome if the tests are negative. The test values can vary from time to time and may even be negative on rare occasions. However, if you have symptoms and the tests are negative at that time then you need to find another cause. ...Read more
I TOOK SOME LABS ANA SCREEN "YOUR VALUE" SAYS SEE TITER, HEX LUPUS ANTICOAGULANT IS 6 (NEGATIVE), SED RATE 3 AND ANA QUANT IS 320. WHAT DOES THIS MEAN?
Upload onto HT Prime: Rather than getting into hypotheticals in this forum (that's lmtd to 400 characters), you're best off starting a consult in HealthTap Prime. If you've obtained a computer copy of the lab results, as you'll be able to upload it in HealthTap Prime using the paperclip icon. You'll also get a doctor to go over it with you LIVE. You can ask questions & get responses in real time. It'll give best answer ...Read more
40yr old Fem Sed Rate Rising (Cont 2) History: Pos ANA, FM, Lupus Anticoagulant, Hypothyroidism, LE Edema. What does all this mean?
See your MD: The positive ANA and lupus anticoag may be associated with potential for blood clotting issues and clearly represent autoimmune disease potentially, of which the hypothyroidism may be a part. You must be seen by an hematologist or immunologist and be evaluated for systemic autoimmune issues. The elevated sed rate is also associated with inflammatory disease. Feel better! ...Read more
I tested weakly positive for lupus anticoagulant. I have been on baby aspirin for 2months now, can I have a successful pregnancy on that alone?
See details: A low positive test is not clinically significant so no preventative therapy is needed. There is no evidence that low dose ASA has any value in this situation. ...Read more
When testing for Antiphospolipid Antibody Syndrome, does taking baby aspirin affect the Lupus Anticoagulant (PTT-LA, dRVVT) test results?
Huy sir. I was pregnant and I had preeclampsia 2mths ago I have positive lupus anticoagulant neg. Ana and low positive antidsdna with ankle pain?
Ok: Are you feeling ok now? You would new a good and thorough medical exam. ...Read more
I am 31, positive mthfr and lupus anticoagulant, chronic pain and swelling of joints&muscles but no rash. If it's not lupus, what is it?
MTHFR Gene mutation: If you'd like to do more reading on the health effects of mthfr gene mutation, here's a great article. .. http://doccarnahan. Blogspot. Com/2013/10/whats-big-deal-about-methylation-update. Html. ...Read more
I have had two miscarriages pcos thin. I tested positive for mthr-gene and lupus anticoagulant. Should I look at IUI next time? I get period 18 days
Before pregnancy!: Make sure that both you ; your hubby (if + for the mthfr 677 or 1298 genotypes), are first being treated with l-methylfolate, p5p, and methylcobalamin (at the minimum), to give any pregnancy a best chance for success. Also, do not take a prenatal vitamin that has regular fa if you are a known mthfr+ person. The regular Folic Acid blocks the receptors that need to let l-mthf through. Pm me! ...Read more
Not necessarily: Although many people with lupus have lupus anticoagulant not all do. And most people with lupus anticoagulant do not have lupus. Patients with lupus are more likely to develop the lupus anticoagulant than the general population so it is one "marker" for the disease. ...Read more
None.: Lac is a laboratory finding of uncertain clinical significance. It predisposes to the development of autoimmune diseases such as lupus erythematosus, vitiligo, pernicious anemia, thyroiditis, inflammatory bowel disease, type I diabetes mellitus and addison's disease. If your rheumatologist has diagnosed you with a particular disorder, medications may be warranted on a clinical basis - not for lac. ...Read more
Anticoagulants are any of a variety of drugs which decrease the body's ability to make or sustain blood clots. They fall, generally, into two categories. Drugs like Aspirin and clopidogrel (plavix) prevent platelets from forming the initial stages of a clot. Drugs like warfarin (coumadin) and dabigatran (pradaxa) block the later process ...Read more
If your "lupus anticoagulant" test is positive, it indicates that your blood may clot more easily than it should (long story on the reason for the backwards name). It is important to know that this is only one of several tests for abnormal clotting that a person with an autoimmune ...Read more
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