Top
20
Doctor insights on: What Does A Positive Lupus Anticoagulant Test Mean

Share
1

1
Hi Dr, I did lupus anticoagulant test. It shows appt (test)-ls 41.7 observed value. Lupus anticoagulant absent means? I have recurrent two abortion

Hi Dr, I did lupus anticoagulant test. It shows appt (test)-ls 41.7 observed value. Lupus anticoagulant absent means? I have recurrent two abortion

Lupus anti coag: Hello ~ people who have recurrent blood clots to the limbs can in some cases be lupus anti-coagulant positive as a cause and there is increased incidence of natural abortion or miscarriage in those cases. You are lupus anticoagulant negative so its irrelevant as a cause to any clotting disorder. Thanks ...Read more

Dr. Boris Aronzon
532 Doctors shared insights

Blood Thinners (Definition)

Agents which slow ;/or break down blood clot formation in up to 3 different ways (they do not decrease blood viscosity; thickness.) (1) some inhibit platelet function (e.g. Aspirin, clopidogrel, etc.). (2) others interfere with some of the clot forming proteins (warfarin, dabigatran, rivaroxaban, etc.), (3) others stimulate the blood clot destruction ...Read more


2

2
Had a lupus anticoagulant test done all was normal except for a high thrombin time at 22.8 is this serious? Factor 5 also runs in my family.

Had a lupus anticoagulant test done all was normal except for a high thrombin time at 22.8 is this serious? Factor 5 also runs in my family.

Normally: a factor V deficiency can cause a prolonged thrombin time But your bleeding time and platelet count should be unaffected. Certain medications and other diseases could also cause elevated thrombin time. ...Read more

See 2 more doctor answers
3

3
Can you explain what a positive test for lupus anticoagulant means?

Can you explain what a positive test for lupus anticoagulant means?

Autoantibodies.: Your body is producing antibodies directed against its own tissues and is likely at increased risk for the development of an autoimmune disease such as lupus erythematosus, rheumatoid arthritis, thyroiditis, vitiligo, infammatory bowel dis or pernicious anemia from gastritis. Lac can cause clotting disorders and miscariages, but is not in and of itself an important predictor of clinical outcomes. ...Read more

4

4
What is the significance of a positive test for lupus anticoagulant?

Blood clots: You are paradoxically at increased risk of having blood clots. Discuss with your doctor. ...Read more

See 1 more doctor answer
5

5
In 11/2014 I was hospitalized with bilateral PE. 3 lupus anticoagulant tests have come back positive, and he said it's primary. Does that mean APS?

In 11/2014 I was hospitalized with bilateral PE. 3 lupus anticoagulant tests have come back positive, and he said it's primary. Does that mean APS?

Almost...: In my experience it can be primary, but other autoimmune disease must be excluded. IgM, followed by IgG anti -cardiolipin antibodies are the most problematic! This is important, since apart from anticoagulants, other drugs may be needed. ...Read more

6

6
What do these mean? Lupus anticoagulant weakly present at 1.30; positive ANA Test 1:40 speckled pattern; negative anticardioliptin and beta2

What do these mean? Lupus anticoagulant weakly present at 1.30; positive ANA Test 1:40 speckled pattern; negative anticardioliptin and beta2

Not much: A weakly present lupus anticoagulant and an ANA of 1:40 are common in the general population, and usually not an indication of an autoimmune disorder. You should visit with the physician who ordered these tests to review them with you however. A test alone does not give any answers. Doctors will need both a patient's history and tests to determine further management. ...Read more

9

9
Can all people diagnosed with the disease lupus test positive to lupus anticoagulant as well?

Not necessarily: This can be seen in the setting of lupus but with other autoimmune diseases as well as some patients can positive for it and not have any associated diseases with it. ...Read more

10

10
I have a positive ana, positive lupus anticoagulant, 386 value for microsomal antibodies. C3 of 113, C4 of 53. A rash on face could it be lupus?

I have a positive ana, positive lupus anticoagulant, 386 value for microsomal antibodies. C3 of 113, C4 of 53. A rash on face could it be lupus?

Yes: If the rash fits the butterfly or discoid rash or the subacute lupus skin lesion. ANA titer is usually high in lupus; you have not listed yours. The C3 and C4 are markers of disease activity and famously nonspecific. Don't try to self-diagnose; your age of 54 is a bit high for new-onset lupus though it's not impossible. ...Read more

See 1 more doctor answer
11

11
I recently had the test for lupus anticoagulant and it was postitive. What are the implications of this?

I recently had the test for lupus anticoagulant and it was postitive. What are the implications of this?

Depends on history: This test should always be confirmed by repeat and other related tests a prior history of multiple late pregnancy losses and /or unexplained clots make the test more ominous. ...Read more

12

12
How many lupus anticoagulant tests are there?

How many lupus anticoagulant tests are there?

Many: There are tests for 3 forms of anticardiolipin antibodies, 3 forms of antiphospholipid antibodies, russell viper coagulation test and tests for specific components of coagulation and general tests (e.g., prothrombin time). ...Read more

13

13
I was recently tested for lupus anticoagulant and it was postitive. Does that mean I have lupus?

No: Having a "lupus anticoagulant" just means there is an abnormality in your clotting mechanism that may make you m, ore easily bleed and, conversely slightly more likely to clot. While this feature may be seen in the disease lupus it does not mean that everyone with this factor has the disease lupus/ there are msany other features of the disease to look for. ...Read more

See 1 more doctor answer
14

14
I tested positive for lupus anticoagulant when I was pregnant but do not now. My brother has as and my son is + for hlab27. Should I get tested again?

Different things: The + hal b-27 not related to lupus anticoagulant (la). The la needs to confirmed, especially if you have a history of clinical problems related to the la like blood clots in the legs, emboli to the lung, strokes, misscarriages, etc. Depending on the clinical picture you may need therapy - many only Aspirin for its anticlotting ability or stronger blood thinners. ...Read more

15

15
Can blood work result in a false positive result for lupus anticoagulant factor?

No: Positive is positive. However, it is the degree of positivity that is clinically important. Low positive values are generally not clinically important. ...Read more

16

16
Pt/inr normal, ptt, activated is 3 seconds prolonged, and in the lupus anticoagulant panel, only abnormality is aptt at 41.4 sec. What does this mean?

Any symptoms?: Why were these tests done? Do you have any symptoms? All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. A slightly prolonged PTT in isolation is not a cause for concern, but it would be important to know why your doctor ordered the tests. Lupus is one of the causes of prolonged ptt. ...Read more

17

17
What does a diagnosis of purpura fulmicans and lupus anticoagulant w/possible phophosilid syndrome mean?

Complicated question: Complicated question. Depends on severity, comlications and treatment. See rheumatologist. ...Read more

19

19
Tested for anti cardiolipin IgM is negative (0.7) but IgG is positive (54.8) normal range of lupus anticoagulant, protein S and protein C activity help?

Not sure: I am not sure I understand the question. I suspect you are being evaluated for a blood clotting disorder and you have an elevated anticardiolipin IgG. One test however does not make the diagnosis of anti-phospholipid syndrome. ...Read more

20

20
Is aps possible if beta-2 glycoprotein, lupus anticoagulant and cardiolipin-ig- (g/m/a)are >0.2. Is test to be repeated in 1-2yrs if once negative?

Is aps possible if beta-2 glycoprotein, lupus anticoagulant and cardiolipin-ig- (g/m/a)are >0.2. Is test to be repeated in 1-2yrs if once negative?

No: It is highly unlikely that you have apa syndrome if the tests are negative. The test values can vary from time to time and may even be negative on rare occasions. However, if you have symptoms and the tests are negative at that time then you need to find another cause. ...Read more

Anticoagulant (Definition)

Anticoagulants are any of a variety of drugs which decrease the body's ability to make or sustain blood clots. They fall, generally, into two categories. Drugs like Aspirin and clopidogrel (plavix) prevent platelets from forming the initial stages of a clot. Drugs like warfarin (coumadin) and dabigatran (pradaxa) block the later process ...Read more


Lupus Anticoagulant (Definition)

If your "lupus anticoagulant" test is positive, it indicates that your blood may clot more easily than it should (long story on the reason for the backwards name). It is important to know that this is only one of several tests for abnormal clotting that a person with an autoimmune ...Read more