Doctor insights on:
What Does A Lung Cancer Cell Look Like
Are A549 cancer cell lines specific to the Adenocarcinoma sub-type of lung cancer, or does it mean something else?
CA cell line: The A549 cell line originated from a male patients bronchoalveolar lung carcinoma. Cell lines often acquire additional mutations that facilitates their growth in culture. They may not retain all of the characteristics of the original tumor. ...Read more
Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more
Often cures: Surgery is the standard of care for stage i and ii lung cancer in the physically fit patient, and should be considered as an option in many patients with stage iiia. Often can be done minimally invasively thorascopically or with a robot. Recovery varies with the level of invasiveness. Lung surgery has best outcomes by a board certified thoracic surgeon. ...Read more
Rarely is cured.: It depends on the stage and if the cancer has spread. Small cell lung carcinoma is usually treated with chemotherapy and radiation. It is one of the most aggressive subtypes of lung cancer. Definitely consult with an oncologist, but patients with small cell should weigh the benefits of participating in treatment offered in clinical trials at university centers. ...Read more
Neuroendocrine tumor: Primary lung lesions are comprised mainly of malignant cells of the bronchus or squamous cell cell and malignant cells of lung glandular tissue or adenocarcinoma of lung. The 3 rd tumor is neuroendocrine or small cell Ca. It is similar in structure and response to the carcinoid of bowel.Tumors other than mets are therefore classed as small cell and non small cell tumors. ...Read more
Yes: Small cell carcinomas may arise in many organs. They typically show evidence of differentiation toward certain glandular structures, called 'neuroendocrine' differentiation. Small cell cancers tend to be rapidly proliferating tumors, and thus may be treated initially with chemotherapy. ...Read more
Not enough space: Let's see: most common category of lung cancer, often but not always tobacco related, treated with surgery if possible but radiation and chemo are often used as well. I suggest you visit the national cancer institute website. It's has good info regarding all kinds of cancers. ...Read more
Nsclc: First of all, a biopsy will need to be done to the lung mass/nodule not only to establish diagnosis but also to find the histology and genetic profile of the cancer. Then, complete staging work-up with pet/ ct scan need to be done to stage the cancer. The treatment will depend on the histology/molecular-genetic mutation status, stage, as well as overall condition and preference of a patient. ...Read more
5yr suvival bystage :
Ia = 49%
ib = 45%
iia = 30%
iib = 31%
iiia = 14%
iiib = 5%
iv = 1%
http://www.Cancer.Org/cancer/lungcancer-non-smallcell/detailedguide/non-small-cell-lung-cancer-survival-rates. ...Read more
One type of lung:
Cancer. It is not easy to explain. There are multiple subtypes within in this type. These are due to smoking and tend to spread locally as compared to early spread through blood for small cell cancer. See this site for more info.
http://www.cancer.gov/cancertopics/pdq/treatment/non-small-cell-lung/patient/page1. ...Read more
It depends;: Unfortunately lung cancer is usually diagnosed in more advanced stages because it can be silent. Depending on the region it involves, symptoms could varry from cough, weight loss, shortness of breath, coughing up blood, affecting voice quality. If cancer is found incidentally in early stages( patient not symptomatic and cancer found incidentally), the cure rate can be excellent. ...Read more
The stage and others: Will depend on the stage and other prognostic factors. In general, the 5 year overall survival for stage 1 is 60-80%., stage 2 is 40-50%; stage 3 is 10-23%, and stage 4 is less than 10%. These however are the statistics obtained when using regular cytotoxic chemotherapy. With more personalized and more targetted therapy-we are hoping the number will improve. ...Read more
No: that is a disorder of the GI system ...Read more
Not good: Stage 3b non-small-cell-lung cancer is a very heterogeneous group of patients and as such there is no unanimous hard data on survival, unlike the earlier stages. Some may benefit from chemo- and radiation therapy to shrink the tumor and be resected. My advice is to go to the most renowned lung cancer specialist that is available to you and hope for the best. ...Read more
Depends on Stage: The answer to that question depends greatly on how advanced the cancer is when it is diagnosed. That, in turn, depends on how big the tumor is, where it is located, whether it has spread locally or all over the body. Generally, the earlier you catch the cancer, the longer the survival is. That is not a 100% "take it to the bank" rule, but it is a general pattern. A number of tests find out stage. ...Read more
Depends: That depends on where the tumor is: if it is spread to a vital organ, it will causes symptoms there, such as a headache if it is in the brain. If the tumor presses on the airway, it can block that part of the lung and cause pneumonia. If it blocks a blood vessel, it can cause problems with blood flow, etc. So, it depends on where it is. ...Read more
Small cell Lung ca: Smoking tobacco significantly increases the risk of small cell carcinoma. Some hypothesize the impact of carcinogenic smoke on the central airways may be the primary mechanism of injury. The earlier in life a person starts smoking, the more often a person smokes, and the more years a person smokes, the greater the risk of lung cancer. ...Read more
Depends on the stage: Once diagnosed you will need to be staged to evaluate for resection. In general patients with early stage lung cancer ( i or ii ), who are healthy enough , should be treated with surgery to remove the cancer. In the more advanced stages (iii or iv) , surgery by itself is usually not curative, and other treatments like chemotherapy and radiation therapy are required. ...Read more
There is no: Cogent role for cyberknife in sclc and it would be a misuse of that expensive technology. Chemotherapy is the standard for limited or extensive disease, thoracic radiotherapy with linac is standard in disease confined to chest. All those warrant preventitive radiotherapy to the brain if the chest responds. ...Read more
Short: With limited stage disease the median survival is less than 2 years and with extensive disease less than a year. Having said that there are 5 year survivors. ...Read more
Bipsy and imaging: The key to diadnosis is the biopsy. This can help determine the subtype which will help guide the course of treatment. Beyond that, the imaging with ct, ct/pet, and MRI will help determine the stage of the cancer. The combination of the stage and the subtype of the cancer will help with treatment decisions as well as prognosis. ...Read more
Deoxygenated blood enters the lungs from the right side of the heart and travels to the lungs. When you inspire, oxygen flows into the lungs, transverses the capilliares and attaches to hemoglobin down a gradient. At the same time, co2 diffuses into the capilaries and is expelled with exhalation. Oxygen rich blood then flows to the left side of the heart and into the ...Read more
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