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Doctor insights on: What Chromosome Is Affected By Down Syndrome

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Dr. Jay Park
Board Certified, Pediatrics
44 years in practice
7M people helped
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How do I make a punnutt square for Down Syndrome. Yes, it's a chromosome defect, but it can also be inherited. answer asap. Thanks!

How do I make a punnutt square for Down Syndrome. Yes, it's a chromosome defect, but it can also be inherited. answer asap. Thanks!

See below: Approximately, 92-94% of cases of Down syndrome is the result of nondisjunction of chromosome during the meiosis process. Only 4% of cases are inherited from the faulty chrosome, i.e., translocation. ...Read more

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Dr. Marsha Davis
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22 years in practice
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Dr. Kathryn Akin
631 doctors shared insights

Down Syndrome (Definition)

Down syndrome is a genetic condition in which there is an extra chromosome present. Symptoms may range from mild to severe. Children with Down syndrome share a common physical appearance including a flattened nose, small ears, a small mouth, upward slanting eyes, and a single crease in the ...Read more


Dr. Nikolaos Zacharias
Board Certified, Maternal-Fetal Medicine
20 years in practice
16M people helped
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Is Down syndrome always caused by a defect in the 21 chromosome?

Is Down syndrome always caused by a defect in the 21 chromosome?

Extra chromosome 21.: Either complete or partial trisomy for chromosome 21 is always responsible for down syndrome. ...Read more

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Dr. Marsha Davis
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22 years in practice
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Dr. James Ferguson
Board Certified, Pediatrics
40 years in practice
144M people helped
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Other than down syndrome, what are two diseases that occur when an abnormal number of chromosomes develop?

Many to choose from: Turner syndrome - the 45 xo deletion of one sex chromosome, the klinefelter syndrome, 47 xxy, the edward syndrome-trisomy 18, and many more. ...Read more

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Dr. William Singer
Board Certified, Pediatric Neurology
45 years in practice
5M people helped
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What would be a good way to cure down syndrome? What would be a way to remove the extra chromosome from every cell in the body? I need a good idea. Thanks :)

What would be a good way to cure down syndrome? What would be a way to remove the extra chromosome from every cell in the body? I need a good idea. Thanks :)

No cure: Unfortunately there is no cure for down syndrome. there is research ging on looking ito the possiblity of inactivating one of the three 21 chromosomes, but it is in early stages and it is not known what the outcome would be from doing so ...Read more

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Dr. Marsha Davis
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Dr. James Ferguson
Board Certified, Pediatrics
40 years in practice
144M people helped
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Which type of chromosomal mutation causes down syndrome?

Which type of chromosomal mutation causes down syndrome?

Not mutation,number : Down syndrome is an abnormality of chromosome numbers, not a trait or mutation in the gene code. During conception only one of chromosome of each pair is given by both parents to the fertile egg.If a parent adds their 2 nbr 21chm to the other parents nbr 21, 3 end up in the egg ; the excess 21 causes the all the problems.Rare forms are causes by a extra piece of a 21, but that's another issue. ...Read more

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Dr. William Goldie
Board Certified, Pediatric Neurology
42 years in practice
4M people helped
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Why do Down syndrome patient have their eyes slanted upward, is it caused by the chromosome 21, i need an explanation on why their face look different?

Why do Down syndrome patient have their eyes slanted upward, is it caused by the chromosome 21, i need an explanation on why their face look different?

In the genes: All of our features are determined by our genes. The appearance of your eyes, nose, mouth, hair color, skin color, among other features are all inherited. When there is a defect in the gene coding, changes can occur. Facial features can change with in utero exposure such as alcohol (fas syndrome). For downs, the extra 21 causes low ears, slanted eyes, simian crease as well as organ problems. ...Read more

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Dr. Robert Andrews
Board Certified, Interventional Radiology
30 years in practice
770K people helped
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What are the chances my child will be born with chromosomal abnormalities? I was told my unborn child has echogenic bowels, that i tested higher for the risk of Down syndrome and as a carrier of the cystic fibrosis trait

There : There are several ultrasound findings that can suggest down sysndrome, and echogenic bowel is one of them. There could be other explanations for that finding, though. It sound like you will need some testing to find out what's going on. The two tests used most commonly are amniocentesis and chorionic villous sampling. Each has its own risks and benefits, so you should discuss them with your obstetrician. I would suggest that you do this sooner than later, and regardless of whether the outcome might lead you to terminate the pregnancy. ...Read more

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Dr. Olga Nilova
Board Certified, Pediatrics
214K people helped
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What body systems are affected by down syndrome?

What body systems are affected by down syndrome?

Multi-system: Heart, thyroid, eyes, iq are the most common to be affected. The child may have a slight problem or a significant impairment in one or several of those areas. ...Read more

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Dr. James Ferguson
Board Certified, Pediatrics
40 years in practice
144M people helped
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Which parts of the nervous system are affected by down syndrome?

Confusing question: Every cell of the nervous system has the ds chromosome pattern so the point of your question is confusing their brain acquires & processes information in a qualitatively different way. They acquire words/language & developmental milestones later. If you have a more specific question, start over & define it clearly. ...Read more

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Dr. James Ferguson
Board Certified, Pediatrics
40 years in practice
144M people helped
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What population is affected by down syndrome?

What population is affected by down syndrome?

Confusing question: Down syndrome is present in any racial, ethnic, social, economic or other group in any country in the world. It can occur to women giving birth at any age but is more common in older mothers. ...Read more

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Dr. Marsha Davis
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