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Doctor insights on: What Chemotherapy Induces Peripheral Neuropathy

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What chemotherapy induces peripheral neuropathy?

What chemotherapy induces peripheral neuropathy?

Some: There are some chemo that can give you peripheral neuropathy for instance taxane (docetaxel, paclitaxol), vinca alkaloids ( vincristine), platinum ( oxaliplatin, cisplatin, carboplatin) etc. ...Read more

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Dr. Olav Jaren
1,344 doctors shared insights

Nerve Damage (Definition)

A complete nerve transection will leave an area totally numb. The distribution of the numbers depends upon where the nerve was cut. A partial nerve injury may leave the area tingly or incompletely numb. Finally even if the nerve is not cut the swelling and bruising to the tea can affect the nerve as well. Usually we consider sharp penetrating injuries as likely having nerve lacerations when sensation is lost. A hand surgeon can examine the hand and pinpoint the site or extent of nerve injury and recommend ...Read more


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What is axonal peripheral neuropathy?

What is axonal peripheral neuropathy?

Axonal PN: Axonal peripheral neuropathy is an illness that may cause numbness and weakness affecting the feet, legs and sometimes the hands. In this condition the nerve cells (axons) that transmit information become ill. Common causes of this condition are hormonal and blood chemistry disorders...... http://www.ninds.nih.gov/disorders/peripheralneuropathy/detail_peripheralneuropathy.htm ...Read more

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What is peripheral neuropathy?

What is peripheral neuropathy?

In the extremities: The term peripheral neuropathy refers to nerve dysfunction of the extremities. A common example of a peripheral neuropathy would be a diabetic experiencing numbness in their feet. ...Read more

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What causes peripheral neuropathy?

What causes peripheral neuropathy?

Many causes: There are many causes of peripheral neuropathy. Common causes are elevated blood sugar, alcohol, and vitamin B12 deficiency. A common "cause" is idiopathic neuropathy, meaning the cause cannot be found. Other causes include medicine side effects, certain kinds of infections, cancer, inherited causes, chemical exposure, and changes in blood chemistry. ...Read more

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What is sensorimotor peripheral polyneuropathy?

What is sensorimotor peripheral polyneuropathy?

It Effect both: The sensory fiber of the nerve and motor fiber of the nerve. ...Read more

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What exactly is axonal sensorimotor peripheral polyneuropathy?

What exactly is axonal sensorimotor peripheral polyneuropathy?

Answer: Description of a peripheral neuropathy that predominantly affects the axon, wire within nerve, and secondarily affects the myelin, insulation. This characteristically occurs in diabetes, alcohol nutritional problems, porphyria, solvent exposure, amyloidosis, etc. ...Read more

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The symptoms of chemotherapy induced peripheral neuropathy are expected to be?

The symptoms of chemotherapy induced peripheral neuropathy are expected to be?

Peripheral neuropath: Most commonly presented as numbness/decreased sensation and tingling on your fingers and toes (stocking-glove pattern) . When it is worse it can then be presented as pain / discomfort on your hands and feet. ( painful neuropathy). Sometimes, particular chemotherapy like oxaliplatin also can give you cold induced pain. Chemo induced neuropathy - usually is accumulative. ...Read more

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Why does pancreatitis cause peripheral neuropathy?

Why does pancreatitis cause peripheral neuropathy?

Several reasons: Chronic pancreatitis can cause Diabetes mellitus which in turn can cause diabetic neuropathy. Malabsorption of fat soluble vitamins can lead to Vitamin B12 deficiency which can cause a peripheral neuropathy. Chronic pancreatitis patients often suffer from severe chronic abdominal pain which appears to be partly due to a peripheral neuropathy of sorts. ...Read more

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What is the difference between peripheral neuropathic disease and peripheral neuropathy?

What is the difference between peripheral neuropathic disease and peripheral neuropathy?

Disease / Condition: One refers to the disease entity causing the problem the other refers to the condition resulting from the disease. ...Read more

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What kind of test can diagnose Peripheral neuropathy- Paraneoplastic syndromes of the nervous system?

Physical & labs: If physical exam suggests peripheral neuropathy, the workup will include assays for a few of the paraneoplastic autoantibodies known to cause it, and a diligent search for an underlying cancer should be undertaken. This is a difficult workup for physician and patient alike, and I wish you luck. Stay proactive. ...Read more

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What is axonal sensorimotor peripheral polyneuropathy and how is it treated?

What is axonal sensorimotor peripheral polyneuropathy and how is it treated?

Generic: A variety of nerve pathology. Etiologies include alcohol/nutritional, diabetes, solvent or chemical exposure, porphyria, amyloid, causations. Since this is a unique category, should be relatively easy to pin down and design a specific therapy. Medical foods, metanx, could improve a small fibre component, and Lyrica (pregabalin) or Cymbalta could help symptoms. ...Read more

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Does peripheral neuropathy progress?

Yes: It will progress if the original cause of the peripheral neuropathy is not addressed/controlled or corrected. ...Read more

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What are the features of diabetic peripheral neuropathy?

What are the features of diabetic peripheral neuropathy?

Several: Symptoms of diabetic peripheral neuropathy may include: tingling numbness (severe or long-term numbness can become permanent) burning (especially in the evening) pain. ...Read more

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Will a taxane for chemo cause permanent peripheral neuropathy if hereditary pn in family? Any alternative to taxane?

Depends: Taxanes may cause permanent neuropathy in any patient although uncommon. There is increased intolerance to taxanes and preexisting sensory neuropathy. Unless the individual is effected by hereditary neuropathy I am not aware of any data suggesting an increased risk just because the family is affected. Whether taxanes can be replaced depends on disease and for what purpose it is used. ...Read more

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I have Idiopathic Peripheral Neuropathy causing sensory loss in feet. Is the electrical stimulation treatment effective in treating condition?

I have Idiopathic Peripheral Neuropathy causing sensory loss in feet.  Is the electrical stimulation treatment effective in treating condition?

Peripheral neuropath: The treatment of peripheral neuropathy relies heavily on the cause of the nerve damage. The pain of the neuropathy usually controlled with medications. Treatment with the electrical stimulation fields has been investigated and analgesic benefits have been reported, but not consistent. ...Read more

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Peripheral neuropathy = what?

A general term for: "nerve damage". It can take many forms--painful or a loss of sensation/numbness. The causes are multiple. Diabetes is the most common, but exposure to chemicals, neurological diseases, alcoholism, chemotherapy, are also significant causes. ...Read more

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Dr. Adam Lewis
504 doctors shared insights

Peripheral Neuropathy (Definition)

A generic medical term for dysfunction of the nerves that carry information to and from the central nervous system (the ...Read more


Dr. Devon Webster
972 doctors shared insights

Chemotherapy (Definition)

The term chemotherapy typically is used to describe using chemicals to treat ...Read more