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Doctor insights on: What Causes The Bilirubin To Build Up

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What causes the bilirubin to build up?

What causes the bilirubin to build up?

Three mechanisms: High bilirubin that is almost all unconjugated means hemolysis (tearing up red cells too fast) or gilbert's non-disease. If it is mostly conjugated, the bile ducts are obstructed, perhaps by a stone or tumor. If both are way up, probably the liver cells are being damaged. ...Read more

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Bilirubin (Definition)

Bilirubin is the potentially toxic product of heme metabolism. It is formed by breakdown of heme present in hemoglobin, myoglobin, cytochromes, catalase, peroxidase and tryptophan pyrrolase. Eighty percent of the daily bilirubin production comes from hemoglobin. It requires conversion to a water-soluble form before elimination from the body by ...Read more


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What causes high bilirubin?

What causes high bilirubin?

Liver disease: Obstruction of the biliary tract rbc destruction drug and others. ...Read more

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What causes low bilirubin in adults?

What causes low bilirubin in adults?

Don't worry: The lab's reference range is set up so that a few percent of healthy people's values lie below the bottom. Especially if you are not obviously sick, this means nothing. ...Read more

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What causes high bilirubin levels in teenagers?

What causes high bilirubin levels in teenagers?

Many possibilities: There are many possible causes for high bilirubin, but they all come down to the liver either not processing bilirubin properly or the body producing more bilirubin than the liver can process. ...Read more

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What could be the cause of abnormally high bilirubin levels?

High billirubin: Elevation of billirubin can be caused production. Accelerated breakdown of red blood cells. Liver disease one of many functions is to remove from blood stream. Blocked excretion billirubin should be deposited in gall bladder as bile salts any thing blocking exit can raise billirubin. I have simply covered about a couple hundred disease conditions. Need to consult your doctor. ...Read more

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I m having bilirubin level 2.0 . Wat would be cause fa it . Wat I have to do for it get correct the problem?

Continue workup: Your physician probably needs to do some further labs. If you feel well, this is the only abnormality on a chemical profile, and it is indirect bilirubin, and you do not have previous chemical profiles with low bilirubin, you probably have gilbert's non-disease and simply need to know it. Other causes in a person who feels healthy may be medication effect, hemolysis or subtle liver troubles. ...Read more

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Can porphyria cause high bilirubin?

Might occur: Some variants of porphyria can affect the liver and cause abnormal liver testing. You can get answers by analyzing your urinary and serum porphyrin levels, and this could allow interventional approaches to bring under full control. ...Read more

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What would cause bilirubin to jump from 0.3 to 1.0 in ten days?

What would cause bilirubin to jump from 0.3 to 1.0 in ten days?

Lots of things: These are both nice normal values and often this goes unexplained. I once shot my bilirubin way up just by slipping while running and getting an impressive backside bruise -- it got the blood donor center all bothered and i had to tell all. Best wishes. ...Read more

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If your gallbladder is not working right could it cause your bilirubin level to go up?

If your gallbladder is not working right could it cause your bilirubin level to go up?

Seldom: The stone must be in the common bile duct that leads from the liver to the gut. This will raise the conjugated bilirubin. It is a common mistake to think that a gallstone blocking the gall bladder will raise the serum bilirubin. Worth knowing is that maybe 5% of people normally run a high indirect bilirubin (gilbert's) which increased when they get hungry. Causes lots of confusion. ...Read more

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