Doctor insights on:
What Causes Polycystic Kidney Disease
See below: Polycystic kidney disease is a inherited disease in which fluid filled cavities ranging from microscopic to larger sizes upto 10-15 cm occur in the kidneys, causing them to grow very big and loose function. The patients may have no symptoms or present with blood in urine and sometimes kidney pain.Besides controlling high blood pressure there is no definitive treatment yet.Many studies are ongoing. ...Read more
The kidneys are paired organs that lie on either side of the vertebral column. Part of their critical functions include the excretion of urine and removal of nitrogenous wastes products from the blood. They regulate acid-base, electrolyte, fluid balance and blood pressure. Through hormonal signals, the kidneys control the ...Read more
Many things: leading causes are diabetes and high blood pressure, autoimmune disease (like Lupus) affects the kidney and congenital diseases also. toxic chemicals and drugs can harm the renal system. You should review your case with your physician to determine the proper investigation and treatment ...Read more
Inherited disease.: Polycystic kidney disease is an inherited disorder of the kidneys, where numerous numbers of cysts form throughout both, making them appear large & irregular. It is estimated to affect 1 in every 1000. Many cases are clinically silent, & the diagnosis is usually made with ultrasound though definitive diagnosis is made with genetic testing. Long term, hypertension & kidney failure are consequences. ...Read moreSee 1 more doctor answer
Totally unrelated: Apart from the word connection these are totally unrelated conditions. Having 1 does not lead to the other. Polycystic ovarian syndrome (pcos) is a complex disorder affecting the ovaries which may cause irregular cycles, fertility or metabolic problems. Polycystic kidney disease is genetic disorder and comes in two versions, both causing kidney problems, which may end in kidney failure / dialysis. ...Read moreSee 1 more doctor answer
No: They are separate disorders. Polycystic kidney disease is an inherited disorder due to a specific genetic alteration. In pckd, a small number of patients get cysts in the liver as the only other organ affected. The cause of cysts in the ovaries is a completely different process and they are not related. However, both can occur in the same individual. ...Read more
Inherited disease: You inherit polycystic kidney disease, so it is reasonable to be evaluated if you have a parent with polycystic kidneys. Evaluation will likely include a painless ultrasound (sound wave) examination. If you know you have polycystic kidneys, you want to do everything you can to protect their function. At some point, though, you may need dialysis or a transplant. Talk to your doctor. LGromkoMD ...Read more
Cause- unknown: Exact etiology for PKD unknown. Some researchers swear that genetics plays a big role-- hence ADPKD and ARPKD ( autosomal dominant type and recessive type). But then there are other tapers not genetically oriented. Some hypothesize-- something goes wrong in signaling at cellular level during renal development--- pronephro/ mesonephros/ metabephros stages! ...Read more
PKD: Polycystic kidney disease (PKD) can cause both chronic and kidney failure. PKD is a progressive disease that can lead to end stage renal disease in most instances and will lead to chronic in all patients. It is unfortunate that there is not cure for PKD and the overwhelming majority will wind up with end stage renal disease. ...Read more
They don't function: Chronic kidney disease (ckd), also known as chronic renal disease, is a progressive loss in renal function over a period of months or years. Chronic kidney disease is identified by a blood test for creatinine. Higher levels of creatinine indicate a lower glomerular filtration rate and as a result a decreased capability of the kidneys to excrete waste products. ...Read moreSee 1 more doctor answer
Many things: Kidney failure can be from problems before, within and after the kidneys(pre-, intrinsic, post-renal failure).Dehydration or poor blood flow from heart problems, blockage from prostate or urinary flow problems, and many things within the kidney. Infection can do it, too. Diseases such as diabetes and hypertension are main causes, as are medications. ...Read more
Not cured: Other than by kidney transplant. Polycystic kidney disease is not universally fatal. Impaired kidney function can be controlled for a long time by diet ; control of hypertension if present. Occasionally symptomatic cysts can be marsupialised laparoscopically. But, as yet, there is no medical treatment to eliminate the cysts. Many require eventual dialysis or transplant. ...Read more
Proper medication: Minimal change (or nil) disease. Correctly diagnosed by biopsy but frequently diagnosed by the symptoms of proteinuria, edema and intact renal function with a bland urine sediment. This responds to steroid therapy most of the time. The presence of blood in the urine, or failure to respond to steroids indicates need for biopsy of kidney with therapy based on those results. Case needs nephrologist. ...Read more
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