Doctor insights on:
What Causes Pancreatic Cancer
Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more
Probably viral: Pancreatic Ca is a lethal disease of probable viral origin. The tumor begins 15-20 yrs before a clinical lesion can be defined. It appears in the head where painless jaundice is seen, in the body with symptoms of invasion of celiac plexus and tail with pseudo varices of vasa brevia. Even with surgery for 10% of patients the survival here is 10%. Chemo with gemzar (gemcitabine) and Abraxane used. ...Read more
Probable viral: Pancreas cancer starts out as an intraductal lesion similar to breast DTIC (dacarbazine). It smolders within the ductal system for 15-20 yrs before first signs of ductal wall invasion to become an early pancreatic carcinoma. The TAA that are expressed early are oncofetal in origin and are suppressed at birth to reappear in the tumor as the oncogenic protein. Transformation probably viral induced. ...Read more
So do we: Pancreatic cancer seems to be a spontaneous event and because it is internal with no early symptoms, is rarely detected until it has spread beyond meaningful treatment. No one knows the cause. There is much investigation being done to provide earlier detection and discover the cause. ...Read more
Been having white globs in my stool that float. What could cause besides pancreatic cancer? Could it be cancer? I had pancreatitis a few years ago.
Doubt its cancer: Floating stool without much color usually indicates poor absorption of fat from your diet. A poorly functioning gallbladder, pancreas or small intestine can be involved. While pancreas cancer can cause such symptoms this is not the usual way cancer is found and 29 is a bit young for pancreas cancer but you should see your doctor to get the other issues on the list checked. ...Read moreSee 1 more doctor answer
Multifactorial: Pancreatic cancer (adenocarcinoma) is caused by the accumulation of mutations in the dna of cells that line the pancreatic duct. Smokers, diabetics, and people with chronic pancreatitis are at increased risk, as are some people with familial (genetic) syndromes. Another type, neuroendocrine (like steve jobs) arise from hormone-producing cells and some are related to inherited cancer syndromes. ...Read moreSee 1 more doctor answer
Yup...: Commonly yellow skin; +/- belly pain; weight loss; new onset diabetes and depression. Pancreas tail makes hormones: insulin, gastrin, glucagon - these cause symptoms. Head/body make digestive juice, and engulf the duct draining the liver into the gut. This is a very nasty cancer. ...Read more
Unsure of question!: Do YOU have pancreas cancer? That is very rare in someone in their 30s. No one knows what causes pancreas cancer. Symptoms are usually upper mid-abdominal pain near the breast bone, often after eating going into the back, weight loss, loss of appetite, change in taste/smell sensation, blood clot in leg, depression. Early pancreas cancer's best chance for cure is surgery. ...Read more
Pancreatic cancer: Pancreatic cancer (p) is due to dna mutations, and there are three ways that we can damage our dna. We can be born with a dna mutation inherited from either parent, we can damage our dna by smoking, or our dna can be damaged by chance. Risk factors for p are increasing age, diabetes, being a male, being obese and eating a high cholesterol diet and being black. ...Read more
Pancreatic cancer: 21 M from LA. Asks: Can pancreatic cancer cause only mild symptoms? How can I know if I have it? ANS: Time will tell. Dr. humor here. All diseases go thru evolution of Sx as does CA pancreas. At your age CA pancreas is VERY rare. Discuss with your Drs & they can help u. If u don't wear your seatbelt start doing that now. Only way 2 tell is 2 take out pancreas. But u get diabetes etc 4 life. ...Read more
Cancer of the pancreas are fast growing abnormal cells. These can be adenocarcinoma that can grow quickly, difficult to diagnose at an early stage & only sometimes can be removed with surgery. Endocrine cancers tend to be slower growing & may produce hormones & are surgically removed. Cystic cancers also may have better success with surgery. All of these can be difficult ...Read more
Abdominal organ. It is digestive organ: it secretes enzymes into the small bowel which break down food and help its absorption. It is also an endocrine organ: it produces hormones involved in sugar control and control of digestion. Insulin is one of these hormones. Diabetics either lack Insulin (type 1 diabetes) or have inadequate ...Read more
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