Doctor insights on:
What Causes Pancreatic Cancer
Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more
Probably viral: Pancreatic Ca is a lethal disease of probable viral origin. The tumor begins 15-20 yrs before a clinical lesion can be defined. It appears in the head where painless jaundice is seen, in the body with symptoms of invasion of celiac plexus and tail with pseudo varices of vasa brevia. Even with surgery for 10% of patients the survival here is 10%. Chemo with gemzar (gemcitabine) and Abraxane used. ...Read more
Probable viral: Pancreas cancer starts out as an intraductal lesion similar to breast DTIC (dacarbazine). It smolders within the ductal system for 15-20 yrs before first signs of ductal wall invasion to become an early pancreatic carcinoma. The TAA that are expressed early are oncofetal in origin and are suppressed at birth to reappear in the tumor as the oncogenic protein. Transformation probably viral induced. ...Read more
So do we: Pancreatic cancer seems to be a spontaneous event and because it is internal with no early symptoms, is rarely detected until it has spread beyond meaningful treatment. No one knows the cause. There is much investigation being done to provide earlier detection and discover the cause. ...Read more
Been having white globs in my stool that float. What could cause besides pancreatic cancer? Could it be cancer? I had pancreatitis a few years ago.
Doubt its cancer: Floating stool without much color usually indicates poor absorption of fat from your diet. A poorly functioning gallbladder, pancreas or small intestine can be involved. While pancreas cancer can cause such symptoms this is not the usual way cancer is found and 29 is a bit young for pancreas cancer but you should see your doctor to get the other issues on the list checked. ...Read more
Multifactorial: Pancreatic cancer (adenocarcinoma) is caused by the accumulation of mutations in the dna of cells that line the pancreatic duct. Smokers, diabetics, and people with chronic pancreatitis are at increased risk, as are some people with familial (genetic) syndromes. Another type, neuroendocrine (like steve jobs) arise from hormone-producing cells and some are related to inherited cancer syndromes. ...Read more
Yup...: Commonly yellow skin; +/- belly pain; weight loss; new onset diabetes and depression. Pancreas tail makes hormones: insulin, gastrin, glucagon - these cause symptoms. Head/body make digestive juice, and engulf the duct draining the liver into the gut. This is a very nasty cancer. ...Read more
Unsure of question!: Do YOU have pancreas cancer? That is very rare in someone in their 30s. No one knows what causes pancreas cancer. Symptoms are usually upper mid-abdominal pain near the breast bone, often after eating going into the back, weight loss, loss of appetite, change in taste/smell sensation, blood clot in leg, depression. Early pancreas cancer's best chance for cure is surgery. ...Read more
Pancreatic cancer: Pancreatic cancer (p) is due to dna mutations, and there are three ways that we can damage our dna. We can be born with a dna mutation inherited from either parent, we can damage our dna by smoking, or our dna can be damaged by chance. Risk factors for p are increasing age, diabetes, being a male, being obese and eating a high cholesterol diet and being black. ...Read more
Pancreatic cancer: 21 M from LA. Asks: Can pancreatic cancer cause only mild symptoms? How can I know if I have it? ANS: Time will tell. Dr. humor here. All diseases go thru evolution of Sx as does CA pancreas. At your age CA pancreas is VERY rare. Discuss with your Drs & they can help u. If u don't wear your seatbelt start doing that now. Only way 2 tell is 2 take out pancreas. But u get diabetes etc 4 life. ...Read more
I don't believe it: My physician-colleagues disagree among ourselves about whether aspartame is a health threat of any kind, but I've seen nothing to make me believe it can mutate genes. I saw the 2010 prospective study on the sugary stuff & was underwhelmed -- the numbers are small, there's no obvious mechanism, some confounding variable seemed likely. Why not some nice fruit juice instead? ...Read more
If I had idiopathic PE a year ago and it was caused by pancreatic cancer would I have symptoms of PC yet? Just scared I have PC.
What part of the back does pancreatic cancer cause pain? Is it constant or can the pain come and go? What does the pain feel like?
Back Pain: Pancreas: The pain is usually in the mid back; it may begin intermittently but then may get worse and more constant. Often aggravated by lying down and/or after meals. The pain is often described as "severe." Opioid pain medications van often ameliorate the pain. ...Read more
Maybe: Whether alcohol abuse is an important risk factor for pancreatic cancer isn't clear; smoking clearly is. Abuse alcohol though and you're asking for chronic pancreatitis, a confusingly-named lifetime severe pain syndrome involving damage to the deep nerves of the area. You don't want that, or any of several other unpleasant sequelae. Best wishes; make smart decisions & drink moderately if at all. ...Read more
Symptom of abdominal:
Many different Cancers in the abdomen can cause early satiety. It is a presenting symptom for stomach, Ovarian cancer as well as pancreatic cancer (sometimes).
If it persists or you are losing weight, you should consult your doctor without a delay of more than 1 or 2 weeks. ...Read more
Iron pancreas cancer: 33 M Ottawa: Can pancreatic cancer cause iron levels to increase? ANS: Can recall no biologically plausible mechanism for this to happen. But discuss with your Drs who know you and your metabolism best. ...Read more
Friend's brother died of pancreatic cancer at 32. Used to be a drinker. What would cause it so early?
Possible viral cause: Pancreatic cancer begins at least 15 years before an early invasive lesion is present. Teen agers have been reported with panc. CA. The probable cause is a virus getting into the tissues to cause transformation though disease like melanoma and chronic pancreatitis are associated with higher incidence. ...Read more
Many possible reason: Nausea is a non-specific symptom and can occur for many different reasons or diseases affecting the abdomen. It can originate in any part of the digestive tract. So you need to get a check up with your doctor and seek medical therapy. You may benefit from cusing anti nausea pills (there are several different ones that can help). Any liver dysfunction (this is common with pancreatic Cancer) can cause ...Read more
No: More likely is cholelithiasis with common duct stones and alcohol abuse ...Read more
Nerve root relief: Back pain associated with pancreatic cancer is due to compression by the tumor on the celiac plexus nerves that run along the spine. Leaning forward could theoretically cause pain relief by opening the disk spaces and relieving the tension off of the celiac plexus. Leanin forward will also allow the pancreas to fall forward, thus relieving pressure off of the nerves that transmit the pain. ...Read more
Could pancreatic cancer cause a tingling type sensation on the left side... sort of under the ribcage? What else could this be?
Pancreatic cancer: It would be unusual for pancreatic cancer to cause a tingling sensation especially under the rib cage. Pancreatic cancer pain is usually a steady, boring type pain in the mid-upper abdomen sometimes alleviated by bending forward. Tingling sensations are usually superficial perhaps involving only the skin or a nerve irritation. ...Read more
Can drinking soda cause a greater risk of pancreatic cancer? I normally drink about one every day (12 oz). I drink v8 fusion too. What to do?
Probably not direct: Probably it is not directly associated with pancreatic cancer. However, as stated by my colleague here- drinking soda is associated with increased risk for obesity and diabetes. In epidemiology study, obesity and diabetes are related to increased risk for pancreatic cancer and so many other medical problems. ...Read more
Variety: There are multiple potential reasons including causing obstruction of GI tract and/or bike duct, toxins from the cancer, and associated treatment side affects like nausea from chemotherapy. There are treatments available for the nausea based upon the cause, don't hesitate to talk to your oncologist. ...Read more
Abdominal organ. It is digestive organ: it secretes enzymes into the small bowel which break down food and help its absorption. It is also an endocrine organ: it produces hormones involved in sugar control and control of digestion. Insulin is one of these hormones. Diabetics either lack Insulin (type 1 diabetes) or have inadequate ...Read more
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