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What Causes Elevated Fumaric Acid In Autism
Is it harmful to have high folic acid levels in body prior to getting pregnant? I have read high folic acid prior to pregnancy my cause autism, true?
ASD are a spectrum of disorders of varying degrees that are characterized by difficulties in social interaction, verbal and nonverbal communication and repetitive behaviors. Autism statistics from the U.S. Centers for Disease Control and Prevention (CDC) identify around 1 in 68 American children as ...Read more
Antenatal factors : Some syndromes cause autistic spectrum disorder & intellectual disability. Chromosomal microarrays find genetic errors in ~15% of kids with ASD. Maternal low folate (folic acid) levels at conception, rubella, "flu", obesity, advanced age & alcohol/drug use from 3 wks.post-conception-term are some epigenetic factors that alter function, but not structure or sequence, of fetal genes & increase risk of ASD. ...Read more
Autism's a pervasive: Developmental disorder affecting many aspects of function. It's a challenge for child & family. Anyone may regress to a lower level of function when overwhelmed but a child with autism is more easily overwhelmed by the world even with excellent family & therapeutic support. Regression indicates something is overwhelming the child. Strive to identify the cause while continuing support. ...Read moreSee 1 more doctor answer
Genetics: The main cause of autism is thought to be genetic with environmental injury or toxin. Symptoms are language delay or loss, social incompetence, repetitive stylized behaviors or movements. The nimh has a great website for all things to do with ad. http://www.nimh.nih.gov/health/publications/a-parents-guide-to-autism-spectrum-disorder/what-are-the-symptoms-of-asd.shtml. ...Read moreSee 1 more doctor answer
Some new ideas: There are some interesting findings that emerged initially when studying families with more than one affected autistic child. Chromosome micro array tests have shown minor, significant distortions of genetic info carried in the chms of these kids. The same defects have been seen in other autistic kids but not always the same locations. This would suggest events prior to or at conception/not latr. ...Read moreSee 2 more doctor answers
No known cause: There is currently no known cause. A diagnosis is usually made after a psychiatrist or physician obtains a complete history and physical and bases the diagnosis on specific criteria. Often a test called the ados can provide further information in making the diagnosis. ...Read more
Multiple causes: Most often these are individuals with a genetically based vulnerability, and inadequate biological screeening out of dietary and environmental toxins and deficiecies lead to abn in information processing and if unrecognized the indiv copig strategies lead to behavioral problems. Is need good accurate dx, then support to address information processig pbms, and diet nutritional change and support. ...Read more
No: Although it is likely that environmental exposures have contributed to the recent rise in autism, there is no credible evidence that the MMR vaccine has caused or contributed to increased autism. The study that first raised the concern has now been discredited as fraudulent. Autism is more common in babies born near superfund sites or with high levels of organophosphate pesticides. ...Read moreSee 14 more doctor answers
One of the hallmarks: Of autistic spectrum disorder is an uneven cognitive profile, doing as well if not better than same-age peers in some areas while having difficulty in others. For example, rote memory & non-verbal problem-solving can be excellent, while social communication & reciprocal social interactions are areas of difficulty. ...Read moreSee 1 more doctor answer
No: Obstructive sleep apnea is caused by upper airway collapse or flaccidity. It can also be due to enlarged tonsils and adenoids. Autistic patients can suffer from osa, but osa has not be found to cause autism, although children with autism can have worsened autistic symptoms from untreated osa. ...Read moreSee 1 more doctor answer
Autistic Spectrum: Disorder is a neurodevelopmental disorder diagnosed by history ; clinical observation of qualitative impairments in social communication ; social reciprocity + stereotypical, repetitive, non-functional motor movements or narrow , restricted areas of interest. Genetic ; epigenetic (factors that change function, but not structure or sequence of fetal genes) are the major known causes, . ...Read more
There are many known: Causes: > 30 known syndromes, "copy repeat errors" in small bits of dna in certain genes, factors that change the function of certain fetal genes early in pregnancy, (e.g., toxins, viruses & ? Folic Acid levels). Specific atypical white matter development is seen on brain mri's in infants long before they show clinical signs of asd. The ? Is, what triggers the expression of the altered genes. ...Read moreSee 1 more doctor answer
Genetic: Leading theories include strong genetic predisposition as we know that autism runs in families. There are twin studies that support this from leading universities. Sometimes "chunks" of DNA are missing, or duplicated. We also know of anatomic brain differences in children on the spectrum versus "neurotypical" kids. The way their "brains are wired" is "different" we are learning. ...Read more
A neurodevelopmental disorder affecting three areas: abnormal socialization, communication, and restricted interests with repetitive patterns of behavior. It is usually detected in the first two years of life. Cause is unknown but strong evidence points to an interplay between ...Read more
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