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Doctor insights on: What Causes Elevated Cpk

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Can a charley horse cause your CPK level to be elevated?

Can a charley horse cause your CPK level to be elevated?

Muscle enzyme: CPK elevations are seen in muscle disease, acute cardiac events, muscle trauma (rhabdomyolysis) but also, in weight lifters, and marathon runners. So, can be rather serious or benign. Perhaps, a severe localized cramp could cause enough muscle trauma to raise the level modestly, but, if significantly up, need to test further and uncover the etiology. ...Read more

Creatine Kinase (Definition)

Creatine kinase is an enzyme found in muscles throughout the body. There are different subtypes of the enzyme, called isoforms, which predominate in different organs. For instance, the isoform in skeletal muscles is different from that which is most heavily found in the heart muscle. A blood tests detects levels of this in the body, for example if ...Read more


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What could cause an elevated creatine kinase test?

What could cause an elevated creatine kinase test?

Muscle injury: Creatinine kinase is released from injured or dead muscle cells, be those skeletal, cardiac of smooth muscle cells. Renal failure is also associtated with modestly elevated levels. ...Read more

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Does a febrile illness cause elevated CPK level and sed rate?

Does a febrile illness cause elevated CPK level and sed rate?

It should not: Febrile illnesses by themselves should not elevate CPK and usually will not elevate a sed rate (at least not signifcantly). Certainly certain diseases and illnesses can but usually not with the common viruses etc. ...Read more

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What do elevated CPK levels mean when exercise is not a factor?

What do elevated CPK levels mean when exercise is not a factor?

Muscle or heart: CPK can be released from damaged or inflamed muscles, including the heart muscle. Some muscle diseases that cause weakness and pain in the muscles can elevate cpk, as can any muscle injury (including an injection into the muscle). Heart attacks and other heart muscle injury or inflammation can also raise the cpk. There are tests to determine the source of the cpk. ("fractionation" of cpk). ...Read more

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What causes CPK levels in the 5000 range and what problems would it cause?

What causes CPK levels in the 5000 range and what problems would it cause?

Lots of causes: Elevated CPK indicates muscle damage and can be resolving or ongoing. There are many causes of this, but the main issue is that it can lead to kidney failure since the muscle breakdown proteins aren't filtered well by the kidneys. Also, ongoing muscle damage can lead to compartment syndrome, a surgical emergency. ...Read more

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What if my CPK is only mildly elevated shld I be concerned? Sed is also only mildly elevated

What if my CPK is only mildly elevated shld I be concerned? Sed is also only mildly elevated

Need more data: How high is mildly? Ask your doc to check antinuclear antibodies and other tests for autoimmune diseases. ...Read more

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I have lost strength on my body due to CPK elevated and it been like these for four weeks now. What to do?

I have lost strength on my body due to CPK elevated and it been like these for four weeks now. What to do?

Muscle inflammation: Elevated CPK can occur with inflamed muscle tissue. This can occur secondary to meds (example statins), injury to muscle groups (causing rhabdomyolisis), or connective tissue disorders (autoimmune reactions) like polynyalgia rheumatica. ...Read more

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What do elevated CPK and aldolase mean?

What do elevated CPK and aldolase mean?

Muscle injury: CPK (an old term) is a marker of injury to muscle, be it skeletal, cardiac or smooth muscle. Aldolase is a non-specific marker of tissue injury and does not add any more information. Why did you have the tests done? What were the findings of other tests? ...Read more

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What would be some reasons for elevated sed and CPK along with low iron count? Should I be concerned?

What would be some reasons for elevated sed and CPK along with low iron count? Should I be concerned?

Yes: If "low iron count" is a pop term for anemia (low hemoglobin / hematocrit) and/or serum iron itself is low, this is always worrisome and your physician must either continue working you up or give you an explanation and suggested treatment. If you are having muscle pain, an elevated CPK would confirm but not prove a clinical impression of a myositis / rhabdomyolysis & lead to workup. ...Read more

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I have mctd my CPK levels have been slightly high for over a year its always between 209-305 whole back burns can slightly high levels cause damage?

I have mctd my CPK levels have been slightly high for over a year its always between 209-305 whole back burns can slightly high levels cause damage?

Many causes: When I've checked C (P)K's on students, the ones that are serious about exercise all have values that are "slightly" elevated or more. MCTD can also produce a myositis. And the Plaquenil you're taking can cause CK from heart and/or skeletal muscle. It's not causing your back burning, but if you're weak or short of breath, maybe. How do you FEEL? Https://www. Ncbi. Nlm. Nih. Gov/pubmed/20051753 ...Read more

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If my sed rate and CPK are mildly elevated should I be concerned? And what could be some reasons for the elevation? I also have a low iron count

Inflammation: Usually a mildly elevated CPK and sed rate are hallmarks of inflammation somewhere in the body.

Chronic inflammation can also make you prone to being anemic, so get that checked out with some common blood tests. ...Read more

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What would be the cause of my 27 yo husband being diagnosed with rhabdomyolysis? We went to the local ER because my husband was having trouble with his acid re-flux. While there they had ran a couple of test and found his CPK (?) levels were extremely el

What would be the cause of my 27 yo husband being diagnosed with rhabdomyolysis? We went to the local ER because my husband was having trouble with his acid re-flux. While there they had ran a couple of test and found his CPK (?) levels were extremely el

If: If the er could not uncover the reason why he went into rhabdomyolysis, then you may never know. I will list some common causes for you, maybe this will help:

muscle trauma or crush injury
burns (severe)
physical torture
prolonged lying down
prolonged coma
severe muscle contractions from seizures
cocaine use
increased body temperature
extreme physical activity
drug and alcohol intoxication
low electrolytes
genetic muscle diseases
near drowning
low body temperature),
medications: most commonly statins, which are used to treat high cholesterol; psychiatric medications, anesthesia medications, HIV medications, colchicine (used for gout)
viruses and some bacteria
untreated hypothyroidism (low thyroid level)
myopathies (muscle diorders)
snake venom

best of luck. ...Read more

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What does it mena to have an elevated total creatine kinase?

What does it mena to have an elevated total creatine kinase?

CPK: Ck is a polycomponent muscle enzyme. The ck mb is the muscle-brain part of ck total. That is why the lower value for mb. The lab normals would tell whether these are elevated or not. Elevations are usually from muscle damage and the mb is found in heart. ...Read more

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What can be the cause of low serum creatine kinase? Level is 26 iu/L?

What can be the cause of low serum creatine kinase? Level is 26 iu/L?

Means nothing: Reference ranges are set so that several percent of healthies fall outside on either end. Stop worrying. Ask your physician about what kind of aerobic fitness would be right for you. ...Read more

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Elevated total creatine kinase with normal isoenzymes. What does this mean?

Elevated total creatine kinase with normal isoenzymes. What does this mean?

CPK: Ck is a polycomponent muscle enzyme. The ck mb is the muscle-brain part of ck total. That is why the lower value for mb. The lab normals would tell whether these are elevated or not. Elevations are usually from muscle damage and the mb is found in heart. ...Read more

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Is myosithis something to worry about when it cause high CPK elevation due to injury calves muscle?

Is myosithis something to worry about when it cause high CPK elevation due to injury calves muscle?

Whoa: Myositis does not result from injury. If your CPK is up from a physical injury to your calf muscles, it's to be expected. If you exercise hard and often, your CPK will be higher -- often much higher -- than the lab's reference range in any case. If you do indeed have an illness in the "myositis" family of muscle diseases unrelated to fitness or injury, you will realize it. ...Read more

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If your kidneys are damage due to elevated CPK because of a small injury in your calves...What should a person do and if this is a serious matter?

If your kidneys are damage due to elevated CPK because of a small injury in your calves...What should a person do and if this is a serious matter?

Rhabdo: Rhabdomyolyis if severe enough can cause acute renal failure and the need for dialysis. A mild case may just cause transient elevation of your renal function. Ask your doc about your specific case. ...Read more