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Doctor insights on: What Causes Elevated Cpk

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Can a charley horse cause your CPK level to be elevated?

Can a charley horse cause your CPK level to be elevated?

Muscle enzyme: CPK elevations are seen in muscle disease, acute cardiac events, muscle trauma (rhabdomyolysis) but also, in weight lifters, and marathon runners. So, can be rather serious or benign. Perhaps, a severe localized cramp could cause enough muscle trauma to raise the level modestly, but, if significantly up, need to test further and uncover the etiology. ...Read more

Creatine Kinase (Definition)

Creatine kinase is an enzyme found in muscles throughout the body. There are different subtypes of the enzyme, called isoforms, which predominate in different organs. For instance, the isoform in skeletal muscles is different from that which is most heavily found in the heart muscle. A blood tests detects levels of this in the body, for example if ...Read more


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What could cause an elevated creatine kinase test?

What could cause an elevated creatine kinase test?

Muscle injury: Creatinine kinase is released from injured or dead muscle cells, be those skeletal, cardiac of smooth muscle cells. Renal failure is also associtated with modestly elevated levels. ...Read more

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Does a febrile illness cause elevated CPK level and sed rate?

Does a febrile illness cause elevated CPK level and sed rate?

It should not: Febrile illnesses by themselves should not elevate CPK and usually will not elevate a sed rate (at least not signifcantly). Certainly certain diseases and illnesses can but usually not with the common viruses etc. ...Read more

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What do elevated CPK levels mean when exercise is not a factor?

What do elevated CPK levels mean when exercise is not a factor?

Muscle or heart: CPK can be released from damaged or inflamed muscles, including the heart muscle. Some muscle diseases that cause weakness and pain in the muscles can elevate cpk, as can any muscle injury (including an injection into the muscle). Heart attacks and other heart muscle injury or inflammation can also raise the cpk. There are tests to determine the source of the cpk. ("fractionation" of cpk). ...Read more

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What causes CPK levels in the 5000 range and what problems would it cause?

What causes CPK levels in the 5000 range and what problems would it cause?

Lots of causes: Elevated CPK indicates muscle damage and can be resolving or ongoing. There are many causes of this, but the main issue is that it can lead to kidney failure since the muscle breakdown proteins aren't filtered well by the kidneys. Also, ongoing muscle damage can lead to compartment syndrome, a surgical emergency. ...Read more

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What if my CPK is only mildly elevated shld I be concerned? Sed is also only mildly elevated

What if my CPK is only mildly elevated shld I be concerned? Sed is also only mildly elevated

Need more data: How high is mildly? Ask your doc to check antinuclear antibodies and other tests for autoimmune diseases. ...Read more

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I have lost strength on my body due to CPK elevated and it been like these for four weeks now. What to do?

I have lost strength on my body due to CPK elevated and it been like these for four weeks now. What to do?

Muscle inflammation: Elevated CPK can occur with inflamed muscle tissue. This can occur secondary to meds (example statins), injury to muscle groups (causing rhabdomyolisis), or connective tissue disorders (autoimmune reactions) like polynyalgia rheumatica. ...Read more

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What do elevated CPK and aldolase mean?

What do elevated CPK and aldolase mean?

Muscle injury: CPK (an old term) is a marker of injury to muscle, be it skeletal, cardiac or smooth muscle. Aldolase is a non-specific marker of tissue injury and does not add any more information. Why did you have the tests done? What were the findings of other tests? ...Read more

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What would be some reasons for elevated sed and CPK along with low iron count? Should I be concerned?

What would be some reasons for elevated sed and CPK along with low iron count? Should I be concerned?

Yes: If "low iron count" is a pop term for anemia (low hemoglobin / hematocrit) and/or serum iron itself is low, this is always worrisome and your physician must either continue working you up or give you an explanation and suggested treatment. If you are having muscle pain, an elevated CPK would confirm but not prove a clinical impression of a myositis / rhabdomyolysis & lead to workup. ...Read more

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I have mctd my CPK levels have been slightly high for over a year its always between 209-305 whole back burns can slightly high levels cause damage?

I have mctd my CPK levels have been slightly high for over a year its always between 209-305 whole back burns can slightly high levels cause damage?

Many causes: When I've checked C (P)K's on students, the ones that are serious about exercise all have values that are "slightly" elevated or more. MCTD can also produce a myositis. And the Plaquenil you're taking can cause CK from heart and/or skeletal muscle. It's not causing your back burning, but if you're weak or short of breath, maybe. How do you FEEL? Https://www. Ncbi. Nlm. Nih. Gov/pubmed/20051753 ...Read more

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If my sed rate and CPK are mildly elevated should I be concerned? And what could be some reasons for the elevation? I also have a low iron count

Inflammation: Usually a mildly elevated CPK and sed rate are hallmarks of inflammation somewhere in the body.

Chronic inflammation can also make you prone to being anemic, so get that checked out with some common blood tests. ...Read more

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What would be the cause of my 27 yo husband being diagnosed with rhabdomyolysis? We went to the local ER because my husband was having trouble with his acid re-flux. While there they had ran a couple of test and found his CPK (?) levels were extremely el

What would be the cause of my 27 yo husband being diagnosed with rhabdomyolysis? We went to the local ER because my husband was having trouble with his acid re-flux. While there they had ran a couple of test and found his CPK (?) levels were extremely el

If: If the er could not uncover the reason why he went into rhabdomyolysis, then you may never know. I will list some common causes for you, maybe this will help:

muscle trauma or crush injury
burns (severe)
physical torture
prolonged lying down
prolonged coma
severe muscle contractions from seizures
cocaine use
increased body temperature
extreme physical activity
drug and alcohol intoxication
low electrolytes
genetic muscle diseases
near drowning
low body temperature),
medications: most commonly statins, which are used to treat high cholesterol; psychiatric medications, anesthesia medications, HIV medications, colchicine (used for gout)
viruses and some bacteria
untreated hypothyroidism (low thyroid level)
myopathies (muscle diorders)
snake venom

best of luck. ...Read more

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What does it mena to have an elevated total creatine kinase?

What does it mena to have an elevated total creatine kinase?

CPK: Ck is a polycomponent muscle enzyme. The ck mb is the muscle-brain part of ck total. That is why the lower value for mb. The lab normals would tell whether these are elevated or not. Elevations are usually from muscle damage and the mb is found in heart. ...Read more

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What can be the cause of low serum creatine kinase? Level is 26 iu/L?

What can be the cause of low serum creatine kinase? Level is 26 iu/L?

Means nothing: Reference ranges are set so that several percent of healthies fall outside on either end. Stop worrying. Ask your physician about what kind of aerobic fitness would be right for you. ...Read more

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Elevated total creatine kinase with normal isoenzymes. What does this mean?

Elevated total creatine kinase with normal isoenzymes. What does this mean?

CPK: Ck is a polycomponent muscle enzyme. The ck mb is the muscle-brain part of ck total. That is why the lower value for mb. The lab normals would tell whether these are elevated or not. Elevations are usually from muscle damage and the mb is found in heart. ...Read more

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Is myosithis something to worry about when it cause high CPK elevation due to injury calves muscle?

Is myosithis something to worry about when it cause high CPK elevation due to injury calves muscle?

Whoa: Myositis does not result from injury. If your CPK is up from a physical injury to your calf muscles, it's to be expected. If you exercise hard and often, your CPK will be higher -- often much higher -- than the lab's reference range in any case. If you do indeed have an illness in the "myositis" family of muscle diseases unrelated to fitness or injury, you will realize it. ...Read more

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If your kidneys are damage due to elevated CPK because of a small injury in your calves...What should a person do and if this is a serious matter?

If your kidneys are damage due to elevated CPK because of a small injury in your calves...What should a person do and if this is a serious matter?

Rhabdo: Rhabdomyolyis if severe enough can cause acute renal failure and the need for dialysis. A mild case may just cause transient elevation of your renal function. Ask your doc about your specific case. ...Read more

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About two weeks ago I went to see the ER because I had a small injury in my calves muscle and elevated my cpk, what should do to bring it down?

About two weeks ago I went to see the ER because I had a small injury in my calves muscle and elevated my cpk, what should do to bring it down?

Fluids and rest: Make sure you follow any medical recommendations provided at the er first and foremost. The best ways to get CPK levels back down is to hydrate yourself thoroughly and then to rest so that you will not cause any more trauma to your muscles. I would follow up with your primary care provider. Stay safe! ...Read more

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Ok im about to take a drug and physical exam for a job. But my CPK has been elevated for a month now due to a small injury in my calves should I worry?

Ok im about to take a drug and physical exam for a job. But my CPK has been elevated for a month now due to a small injury in my calves should I worry?

Physical: This should not alter your drug screen test especially if it were to be negative. Your physical would be expected to be normal if the injury has almost recovered. ...Read more

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I has been feeling very weak for a month in a half due to muscle injury in my calves and it elevated my cpk. What do to?

Feeling tired: If your fatigue is indeed due to muscle damage, which is possible, there is nothing to do other than to give your muscles and yourself enough rest. Hopefully, the damage is reversible and your muscles will restore. Drink plenty of water to get all of the toxins out of your body and make sure your body organs are working normal especially kidneys. Your doc should monitor that. ...Read more

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Mildly elevated CPK and sed low iron abnml TSH but free T4 normal what does all this mean?

Not enough info: How high is the tsh? Any anemia? Other health issues? Any other health history, physical or lab findings? Please provide more info. ...Read more

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Yesterday at ER, EKG normal, troponin normal, CPK high, CKMB normal, they send me home. Today made lab test by myself, Trop normal, CPK and CPKM elevated?

Yesterday at ER, EKG normal, troponin normal, CPK high, CKMB normal, they send me home. Today made lab test by myself, Trop normal, CPK and CPKM elevated?

Unclear question: Total CK may be elevated due to muscular activity and so may be CKMB. You did not provide any values. With normal troponin and evaluation at ER being normal, it is not likely that you have acute heart disease. What did your cardiac cath show? ...Read more

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Mildly elevated CPK level and sed rate. Iron count 11.8 what cld this mean? Cld it be a sign of lupus or something wrong with heart?

Mildly elevated CPK level and sed rate. Iron count 11.8 what cld this mean? Cld it be a sign of lupus or something wrong with heart?

Not specific: Cpk, sed rate and iron count levels are not specific to lupus or heart disease. Several conditions can affect these tests. ...Read more

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Can metobolic disease cause fasciculations. Have high CPK 744 high adolese and low t. Rheumatologist thinks metobolic. Clean emg/ns. Worried als. 36?

Can metobolic disease cause fasciculations. Have high CPK 744 high adolese and low t. Rheumatologist thinks metobolic. Clean emg/ns. Worried als. 36?

Possibly..: The differential diagnosis of ALS is quite extensive, probably too much to post here. EMG often shows both acute and chronic denervation in ALS although conventional MRI is usually normal in ALS. You could pursue a lumbar puncture and/or muscle biopsy for the possibility of some more definitive answers. ...Read more

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What can cause muscle burning with no weakness? Normal CPK aldolase ESR and lactic acid 5 times each...No 1 can figure it out. Horrible pain all day

What can cause muscle burning with no weakness? Normal CPK aldolase ESR and lactic acid 5 times each...No 1 can figure it out. Horrible pain all day

Ouch: Hard to say. Maybe someone called it fibromyalgia which is a pain syndrome without a good explanation. Sounds like over-the-counter pain meds haven't helped. There are pills like Gabapentin that help for various nervy pain problems. Maybe ask about it. ...Read more