Doctor insights on:
What Causes Chrons Disease
Not known yet: The cause seems to be a combination of genetics (different immune defects) and environmental triggers. The subtypes of crohn's disease may also have different immune defects, and for this reason people may respond differently to treatments. Though much more is known now about cd, we still don't know the cause. But stress and some foods can make it worse. Decreasing stressors can help a lot. ...Read more
Autoimmunity.: Genetic predisposition and interaction with pathogens from the environment conspire to cause ibd, which in essence is an autoimmune disorder. Maternal-fetal cell trafficking across the placenta fuels the theory that most if not all autimmune disorders have their origin in fetal (or maternal) stem cells persisting in various organs and stimulating inflammatory response. Stress does not help! ...Read more
Unknown at present: Alzheimer's disease is one type of dementia, conditions marked by of decline in cognitive status & because of problems functioning.In spite of continuing research at this time exact cause is not known but greatest risk factor is old age & some forms run in families. Sometimes other conditions such as depression or low sodium can mimic symptom or worsen QOL so a careful diagnosis is first step. ...Read moreSee 1 more doctor answer
Cause of Hodgkin's: Hodgkin's disease is of unclear etiology. A clone of B lymphocytes undergoes a genetic mutation(possibly caused by a virus) and begins to proliferate without control. The body's immune system reacts to these abnormal cells in the lymph nodes and causes the nodes to swell. The disease can also involve the spleen, liver, bone marrow, and other organs when advanced. The treatment is usually curative. ...Read more
Leg Calve Perthes: Disease can be isolated or familial. Avascular necrosis of the femoral head occurs in growing children. The familial type, caused by heterozygous mutation in the COL2A1 gene on chromosome 12q13, is thought to be multi-factorial, with a recurrence rate of ~3%. LCPD is commonly seen in kids aged 4-10 years, some say 2-12, & is more common in boys than girls. ...Read more
Many things: leading causes are diabetes and high blood pressure, autoimmune disease (like Lupus) affects the kidney and congenital diseases also. toxic chemicals and drugs can harm the renal system. You should review your case with your physician to determine the proper investigation and treatment ...Read more
Autoimmune: The immune system recognizes a protein usually a bacteria protein in your gut and your immune system does its job to clear that particular foreign protein. Unfortunately your gut is the innocent bystander in this process and sustains anywear from mild to severe damage and prevents it from absorbing nutrition. ...Read moreSee 2 more doctor answers
Chronic inflammation: Crohn’s disease is a chronic inflammatory condition of the gastrointestinal tract and it belongs to a group known as inflammatory bowel diseases. It most commonly affects the end of the small bowel (the ileum) and the beginning of the colon, but it may affect any part of the gastrointestinal tract, from the mouth to the anus. Persistent diarrhea, pain, bleeding, weight loss, some of the symptoms. ...Read more
Unknown: While we don't entirely know what causes these, inflammatory bowel disease (ulcerative colitis and crohn's) appears to be caused by an autoimmune mechanism. There is a degree of genetic susceptibility, which seems to be higher in crohn's. However other theories, such as a virus as a cause, may also play a role. There are many other forms of colitis that may mimic these, and only a doctor can tell. ...Read more
Inherited: Gaucher's disease GD is an inherited / genetic metabolic disorder that causes an enzyme deficiency. This deficiency disables the process that allows for the breakdown of a class of compounds called glycolipids causing them to accumulate in abnormal concentration in various organs resulting in damage to these organs. ...Read more
Genes: Wilson's disease is due to mutations in the wilson disease protein (atp7b) gene. Wilson's - konovalov's disease or hepatolenticular degeneration is an autosomal recessive genetic disorder in which copper accumulates in tissues like the liver and cornea; this manifests as neurological or psychiatric symptoms and liver disease. It is treated with medication and sometimes liver transplant. ...Read moreSee 2 more doctor answers
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