Doctor insights on:
What Causes Celiacs Disease
A genetic disease is a disease that is caused by a defect in the genetic (dna) material in a gene(s). It can be inherited and mosy pose a risk to other family members and/or to future children. For many genetic diseases there are molecular tests that allow detection of a change(s) called mutations, we can also detect deltions or other changes to the gene's dna that can also result ...Read more
Celiac Disease: Celiac disease is an auto-immune IgA antibody problem where your own antibodies are attacking the enzymes that break down the products of gluten. It is not a food allergy! that is why mayo clinic labs check IgA levels before even running the other tissue specific tests. ...Read moreSee 1 more doctor answer
Celiac Disease: Celiac disease (gluten-sensitive enteropathy) has three of the following features: villous atrophy; malabsorption, weight loss, or other signs of nutrient or vitamin deficiency; and resolution of the mucosal lesions and symptoms after withdrawal of gluten-containing foods (usually within a few weeks to months). Diarrhea, weight loss, and antibodies against gliadin ...Read more
Autoimmune: The immune system recognizes a protein usually a bacteria protein in your gut and your immune system does its job to clear that particular foreign protein. Unfortunately your gut is the innocent bystander in this process and sustains anywear from mild to severe damage and prevents it from absorbing nutrition. ...Read moreSee 2 more doctor answers
Genes: Wilson's disease is due to mutations in the wilson disease protein (atp7b) gene. Wilson's - konovalov's disease or hepatolenticular degeneration is an autosomal recessive genetic disorder in which copper accumulates in tissues like the liver and cornea; this manifests as neurological or psychiatric symptoms and liver disease. It is treated with medication and sometimes liver transplant. ...Read moreSee 2 more doctor answers
Inherited: Gaucher's disease GD is an inherited / genetic metabolic disorder that causes an enzyme deficiency. This deficiency disables the process that allows for the breakdown of a class of compounds called glycolipids causing them to accumulate in abnormal concentration in various organs resulting in damage to these organs. ...Read more
Prion disease: Creutzfeld jakob is a disease caused by what are referred to as prions. These are small 'virus-like"(but not actual viruses) segments of genetic material that can be transmitted by eating raw flesh infected with the disease(occurs in cannibals) or transmitted via poorly decontaminated surgical equipment that had been exposed to such. ...Read moreSee 1 more doctor answer
Unknown at present: Alzheimer's disease is one type of dementia, conditions marked by of decline in cognitive status & because of problems functioning.In spite of continuing research at this time exact cause is not known but greatest risk factor is old age & some forms run in families. Sometimes other conditions such as depression or low sodium can mimic symptom or worsen QOL so a careful diagnosis is first step. ...Read moreSee 1 more doctor answer
Cause of Hodgkin's: Hodgkin's disease is of unclear etiology. A clone of B lymphocytes undergoes a genetic mutation(possibly caused by a virus) and begins to proliferate without control. The body's immune system reacts to these abnormal cells in the lymph nodes and causes the nodes to swell. The disease can also involve the spleen, liver, bone marrow, and other organs when advanced. The treatment is usually curative. ...Read more
Autoimmune disease: Grave's is a disease in which antibodies against the thyroid stimulating receptors are formed. The initiating event is unknown. These antibodies lock on to and continuously stimulate the receptor so the thyroid kicks out thyroid hormone without regulation producing the classic symptoms of insomnia, anxiety, wt loss, increased appetite, dysthermia, hyperdefecation, bulging eyes / stare. ...Read more
Unknown: While we don't entirely know what causes these, inflammatory bowel disease (ulcerative colitis and crohn's) appears to be caused by an autoimmune mechanism. There is a degree of genetic susceptibility, which seems to be higher in crohn's. However other theories, such as a virus as a cause, may also play a role. There are many other forms of colitis that may mimic these, and only a doctor can tell. ...Read more
What are symptoms of celiacs disease and am I more likely to have it because my grandfather does?
Variable Sx; slight: Celiac can have variable sx, incl gas, bloat, diarrhea, wt loss, rarely gain, constipation, joint aches and pains (often from vitamin d def), fatigue (often from iron def), osteoporosis, swallowing probl, rarely liver probl. Can get screened with blood testing, and/or genetic testing. Assoc with other autoimmune diseases such as ibd, psoriasis, rheum arth, lupus, type 1 diabetes, thyroid disease. ...Read moreSee 1 more doctor answer
Interstitial lung disease is a group of various conditions that affect the thin tissue between the airspaces in the lung. These disorders lead to thickening, fibrosis & scarring of the lung over time, making it difficult for patients to breathe. They can be caused by exposure to environmental toxins, certain drugs, infections, autoimmune disorders, genetic problems ...Read more
In auto immune disease the enemy is from with in . As name implies "auto" is self and "immune " is immune system . One 's own immune system for unknown reason turns against self and destroys or damages tissues or cells . List of auto immune disease are many and growing . End result is destruction of of tissues such as thyroid , pancreas or cells such as white ...Read more
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