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Doctor insights on: What Causes Avascular Necrosis

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Dr. Charles Glueck
464 doctors shared insights

Osteonecrosis (Definition)

-death of bone. This is due 2 loss of blood supply 2 a certain bone part. Common after some injuries such as fractured navicular in the wrist, dislocation of the hip. Some R due 2 drugs , especially steroids, also alcoholism, in these cases it's usually ...Read more


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Can coffee cause avascular necrosis?

Can coffee cause avascular necrosis?

No: Although caffeine isn't good for bone density, regular consumption of coffee doesn't cause avascular necrosis. ...Read more

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Why does steroids cause avascular necrosis?

Why does steroids cause avascular necrosis?

We are not sure: We are not sure but there is a linkage seen whether it may be more related ti the underlying problem for which the steroids are given as treatment in the first place. ...Read more

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Do steriods from chemo cause avascular necrosis?

Do steriods from chemo cause avascular necrosis?

Possibly but others: Although avascular necrosis can be related to corticosteroids it is important to know that there are other causes of avascular necrosis. There is a decrease in blood flow to the area involved. Although corticosteroids can be associated, it depends on dose and time and thus chemo steroids are less likely to be associated. Other causes: alcohol, joint injury and increased pressure ...Read more

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Can avascular necrosis of the shoulders be caused by a work related strain?

Can avascular necrosis of the shoulders be caused by a work related strain?

No: Avascular necrosis can be associated with trauma, if the blood supply to the bone is interrupted by injury. Most of the time, the cause is unknown. Certain diseases such as sickle cell anemia or alcoholism have higher rates of avascular necrosis. It is not associated with strain or sprain type injuries. Steroid use is also a cause of avascular necrosis. ...Read more

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Why is the " corticosteroid administration " can cause " avascular necrosis" ? * i need the mechanism how does the " corticosteroid" work.

Why is the " corticosteroid administration " can cause " avascular necrosis" ?
* i need the mechanism how does the " corticosteroid" work.

Not Known: While it is generally agreed that the key problem in avn is compromised blood flow to the bone, the mechanism by which corticosteroid use contributes to avn is not known. It is important to remember that this is a rare and not a common problem in corticosteroid users. ...Read more

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How does prednisone cause avascular necrosis?

Still unknown: Even though there is this very well-established connection between chronic Prednisone use and avascular necrosis, how this occurs remains unclear. Numerous hypotheses abound. Some argue that increased lipids seen with steroids cause vessels to joints to clog, leading to oxygen starvation & bone death. A more popular view is that vessel (venous) walls undergo thickening, leading to poor blood flow. ...Read more

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Why do steroids cause avascular necrosis of the femur head?

Why do steroids cause avascular necrosis of the femur head?

Unknown: No one really knows for sure. However, it has been shown that steroids cause elevation of lipids. In rabbits, steroids cause collections of lipids called an embolism. The emboli caused avascular necrosis of the femoral heads in the studied rabbits. ...Read more

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Can avascular necrosis cause severe unbearable lower back pain?

Can avascular necrosis cause severe unbearable lower back pain?

Avascular necrosis: Avascular necrosis of the hip? Can definitely cause low back pain. In fact many patients come to the doctor complaining of back pain and not hip pain. But, many other things can cause low back pain as well. Have it checked to see if due to the avn or due to something else. ...Read more

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I have avascular necrosis in my right hip, can it cause lower right back pain?

I have avascular necrosis in my right hip, can it cause lower right back pain?

Yes: Problems with hip pain may eventually cause issues with your back due to how the body tries to adjust to pain by favoring the non painful joint leading to misalignment of your back. ...Read more

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Does chemotherapy cause avascular necrosis? Does having cancer treatments such as chemo or radiation increase my risk of avascular necrosis? .

Does chemotherapy cause avascular necrosis? Does having cancer treatments such as chemo or radiation increase my risk of avascular necrosis?

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Perhaps: Certain chemo and radiation can cause avn. Certain cancers and disease can as well. It is best to discuss this with your oncologist or internist. ...Read more

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Does chemotherapy cause avascular necrosis? Does having cancer treatments such as chemo or radiation increase my risk of avascular necrosis? . .

Possible: Certain therapeutics, although not chemotherapy, that are commonly used in cancer patients can be associated with avascular necrosis (avn). Examples of these agents include: zometa, xgeva (denosumab) and avstin that can be associated with osteonecrosis of the jaw. Dexamethasone and radiation therapy can also cause avn. ...Read more

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Does Flonase nasal spray cause avascular necrosis?

Does Flonase nasal spray cause avascular necrosis?

Probably Not: There is a theoretical concerns that any steroid cause avn. Having said that it would be distinctly unusual, if not un heard of, for normal doses of Flonase to cause avn. ...Read more

Dr. Alan Ali Dr. Ali
2 doctors agreed:
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Why is avascular necrosis caused by steroid use and/or alcohol use?

Dr. Alan Ali Dr. Ali
2 doctors agreed:
Why is avascular necrosis caused by steroid use and/or alcohol use?

Avascular Necrosis: Due to effect on blood vessels, causing interruption of blood supply to the bone. ...Read more

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Is there any connection between current avascular necrosis of hip from no known cause and 15 yr ago subarachnoid hemorrhage of unknown cause? 60 yr

Unrelated: Avascular necrosis of the hip may occur after trauma or associated with use of steroids. The subarachnoid hemorrhage may have been result of aneurysm or trauma. If there were some issue of the hip then, there would have been very obvious signs then. If new issues now, then they are unrelated. ...Read more

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Can hemachromotosis cause avascular necrosis of the ankle joint?

Can hemachromotosis cause avascular necrosis of the ankle joint?

Arthritis, not AVN: Hemochromatosis is associated with development of arthritis that can affect multiple joints, but is not generally associated with avascular necrosis. ...Read more

Dr. Pietro Seni
226 doctors shared insights

Avascular Necrosis (Definition)

Also known as osteonecrosis, this is the death of a bone caused by an interruption of the blood supply. This can result in tiny bone fractures and eventual destruction ...Read more


Necrosis (Definition)

Necrosis is the the death of cells and tissue. In dentistry, root canals are often needed when the pulp tissue inside a ...Read more