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Doctor insights on: What Causes A Positive Ana

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What causes a positive ana?

What causes a positive ana?

Autoimmune disease: ANA (anti-nuclear antibody) is a blood test used by doctors that indicates the presence of an autoimmune condition in which the body's immune system is predisposed to recognize normal things in your body as foreign invaders that need to be attacked. The results are not specific for any particular disease if positive, but are a preliminary test, after which a range of possibilities are considered. ...Read more

Ana (Definition)

An "ana" is a blood test used to screen a person for the possibility of several autoimmune diseases. It is important to remember that this is a screening test and a positive result only indicates more testing may be warranted. No blood test is perfect, and getting to a diagnosis is usually much more complex than drawing blood and looking at a number ...Read more


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What causes positive ANA results?

What causes positive ANA results?

Possibly normal: Up to 5% of healthy people may have a low titer ana. Lupus and other autoimmune diseases and sarcoidosis are possiblities. Diagnosis is on the basis of associated findings, not the ANA by itself. ...Read more

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What can cause a positive ANA 1:160 speckled and 19 ESR levels ?

What can cause a positive  ANA 1:160 speckled and 19 ESR levels ?

Many things: I'd ignore the normal ESR / sed rate. The ANA at this titer is concerning, but means nothing apart from its clinical context. Many women even of your age have positive ana's like this without evidence of illness. If it was ordered as part of a rheumatology workup, it suggests something in the autoimmune / lupus family. Despite the many labs, diagnosis and treatment rest mostly on clinical picture. ...Read more

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What could cause a positive ANA titre of 1:320? Also hilar and mediasternal lymphadenopathy? Possibly related to each other?

What could cause a positive ANA titre of 1:320? Also hilar and mediasternal lymphadenopathy? Possibly related to each other?

My recommendation: 1. ANA, can be nonspecific. Positive usually reflect an autoimmune process such autoimmune hepatitis or SLE, etc. With titer of 1:320, I recommend you see a rheumatologist for further work-up. 2. Hilar and mediastinopathies are concerning. If CT report does raise a concern, you should see a pulmonologist as the first step. Not sure if the two is related or not at this point. ...Read more

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What could cause positive ANA 1:640. I have up mid back pain 1 yr and right flank pain CT of chest clear. Mri ok. Cbc ok. Urine ok .Metabolic ok.

What could cause positive ANA 1:640. I have up mid back pain 1 yr and right flank pain CT of chest clear. Mri ok. Cbc ok. Urine ok .Metabolic ok.

ANAs: Anas typically are not associated with back pain unless neurological symptoms are present to suggest an autoimmune process. The odds are in your favor that is a false positive ANA which is very common. ...Read more

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What would cause a high positive ANA (1:640) speckled, nucleolar with a low positive smooth muscle antibody (1:40) but negative SS-A, SS-B, anti-Smith, RNP, SCL-70, Anti Jo antibodies? Liver disease?

Probably normal: Many people have a positive ANA without being sick. If you also have elevated liver enzymes, a workup for autoimmune hepatitis may be continued, but if there's nothing to suggest a liver problem biochemically, I'd not be in a hurry to diagnose despite anti-smooth-muscle. ANA means nothing apart from the clinical picture. Best wishes. ...Read more

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What are the causes of a positive ANA test result?

What are the causes of a positive ANA test result?

Many: ANA can be positive in many diseases and in many apparently healthy people. By itself , it does not mean much other than pointing to a higher but not certain risk for an individual to develop an autoimmune disease. ...Read more

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What can cause false positives on a ANA test im just concerned and don't want a false positive?

See below: They can occur for a variety reasons such as having a current or chronic infection. However; anas can have positive results and these can occur due to the type of the assay that was performed and can vary from different laboratories. It is is up to your rheumatologist to determine whether or not it is a false positive. ...Read more

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Positive Ana 1:40 homogenous and speckled mixed pattern. What could cause this?

Autoimmune disorder: Lupus or other autoimmune disorder a possibility. Those titre numbers (1:40) are not extremely elevated so it may also be a normal variant. Also other connective tissue disorders possible: polymyositis, rheumatoid, sjogren's, etc. You probably need additional blood work and to possibly see a rheumatologist. ...Read more

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Can syphilis cause a positive ANA test?

No: However lupus can cause the screening test for syphilis (the rpr) to be falsely positive. ...Read more

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Hiv cause positive ana?

Hiv cause positive ana?

See below: Any viral infection can cause a positive ANA but a large number of patients have a false positive ANA without any identifiable cause. ...Read more

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Can spongiotic dermatitis cause a weakly positive ana?

Can spongiotic dermatitis cause a weakly positive ana?

Not necessarily: About 30% of the us population can have a false positive ana. ...Read more

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Can taking Flunarizine for a week cause false positive ANA report?

ANA test: In general the ANA test has a high sensitivity. That means that it is a good screening test but is not as specific for a disease. It can be thrown off by other factors yes. Take a look at the many specific antibodies that can be tested on wikipedia. Its best to go based on clinical suspicion when it comes to antibody workups for Lupus or other similar conditions. http://en.wikipedia.org/wiki/ ...Read more

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Would a negative ANA rule out lymphoma? Does lymphoma cause a positive ANA test result?

It does not: At your age, if you have lymphoma it's probably Hodgkin's. ANA really has nothing to do with malignant lymphoma. If you're worried about big lymph nodest, trust me -- lymphoma nodes are obviously very abnormal. Best wishes, and I hope you'll always stay actively involved with your health. ...Read more

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Tomorrow, I have to do another ANA test, will me taking plaquinil cause a false positive ana?

No: Wondering why you are taking a medication often prescribed for lupus if you don't list either lupus or another reason for the medicine. Anti-nuclear antibody tests aren't reported as "positive" or "negative" but as a titer. They remain an important screening test for lupus. ...Read more