Doctor insights on:
What Causes A Positive Ana
Autoimmune disease: ANA (anti-nuclear antibody) is a blood test used by doctors that indicates the presence of an autoimmune condition in which the body's immune system is predisposed to recognize normal things in your body as foreign invaders that need to be attacked. The results are not specific for any particular disease if positive, but are a preliminary test, after which a range of possibilities are considered. ...Read more
An "ana" is a blood test used to screen a person for the possibility of several autoimmune diseases. It is important to remember that this is a screening test and a positive result only indicates more testing may be warranted. No blood test is perfect, and getting to a diagnosis is usually much more complex than drawing blood and looking at a number ...Read more
Many things: I'd ignore the normal ESR / sed rate. The ANA at this titer is concerning, but means nothing apart from its clinical context. Many women even of your age have positive ana's like this without evidence of illness. If it was ordered as part of a rheumatology workup, it suggests something in the autoimmune / lupus family. Despite the many labs, diagnosis and treatment rest mostly on clinical picture. ...Read more
Juvenile arthritis: More important that tests is how the child is doing treat the patients not the tests. ...Read more
What could cause a positive ANA titre of 1:320? Also hilar and mediasternal lymphadenopathy? Possibly related to each other?
My recommendation: 1. ANA, can be nonspecific. Positive usually reflect an autoimmune process such autoimmune hepatitis or SLE, etc. With titer of 1:320, I recommend you see a rheumatologist for further work-up. 2. Hilar and mediastinopathies are concerning. If CT report does raise a concern, you should see a pulmonologist as the first step. Not sure if the two is related or not at this point. ...Read moreSee 1 more doctor answer
What could cause positive ANA 1:640. I have up mid back pain 1 yr and right flank pain CT of chest clear. Mri ok. Cbc ok. Urine ok .Metabolic ok.
What would cause a high positive ANA (1:640) speckled, nucleolar with a low positive smooth muscle antibody (1:40) but negative SS-A, SS-B, anti-Smith, RNP, SCL-70, Anti Jo antibodies? Liver disease?
Probably normal: Many people have a positive ANA without being sick. If you also have elevated liver enzymes, a workup for autoimmune hepatitis may be continued, but if there's nothing to suggest a liver problem biochemically, I'd not be in a hurry to diagnose despite anti-smooth-muscle. ANA means nothing apart from the clinical picture. Best wishes. ...Read more
What could cause ANA positive spec pat. 1;640. I am seeing a rheumtoligist. No answers! serum protein ok. Lupus neg. Up back pain. Cbc ok. Urine ok.?
+ ANA is not =lupus: + ANA is not = sle. It helps guide the diagnosis of systemic lupus erythematosus we can see a+ ANA in many other settings.Allergies, thyroid disease, other connective tissue diseases and in perfectly normal people. It is not associated with back pain. ...Read moreSee 1 more doctor answer
See below: They can occur for a variety reasons such as having a current or chronic infection. However; anas can have positive results and these can occur due to the type of the assay that was performed and can vary from different laboratories. It is is up to your rheumatologist to determine whether or not it is a false positive. ...Read more
Autoimmune disorder: Lupus or other autoimmune disorder a possibility. Those titre numbers (1:40) are not extremely elevated so it may also be a normal variant. Also other connective tissue disorders possible: polymyositis, rheumatoid, sjogren's, etc. You probably need additional blood work and to possibly see a rheumatologist. ...Read moreSee 1 more doctor answer
ANA test: In general the ANA test has a high sensitivity. That means that it is a good screening test but is not as specific for a disease. It can be thrown off by other factors yes. Take a look at the many specific antibodies that can be tested on wikipedia. Its best to go based on clinical suspicion when it comes to antibody workups for Lupus or other similar conditions. http://en.wikipedia.org/wiki/ ...Read moreSee 2 more doctor answers
It does not: At your age, if you have lymphoma it's probably Hodgkin's. ANA really has nothing to do with malignant lymphoma. If you're worried about big lymph nodest, trust me -- lymphoma nodes are obviously very abnormal. Best wishes, and I hope you'll always stay actively involved with your health. ...Read more
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