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Doctor insights on: What Causes A Hyperosmolar Hyperglycemic State

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What causes a hyperosmolar hyperglycemic state?

What causes a hyperosmolar hyperglycemic state?

Insulin presnt : Common denominator is excessive glucose in (soda), with progessive dehydration in a patient with diabetes who is sti capable of secreting pancreatic Insulin this aborting progressive ketoisis, but not enough to stop raisng bld.Glucose. ...Read more

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Dr. James Lin
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Hyperosmolar Hyperglycemic State (Definition)

Hyperosmolar hyperglycemic state is a complication of diabetes mellitus in which high blood glucose levels cause severe dehydration and an increase in serum osmolarity (relative concentration of solute); it is associated with a high risk of complications, including possible coma and death. It is related to diabetic ketoacidosis (dka), another complication of diabetes, but lacks ...Read more


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What is the definition or description of: hyperosmolar hyperglycemic state?

What is the definition or description of: hyperosmolar hyperglycemic state?

See answer details.: Hyperosmolar hyperglycemic state is a complication of diabetes mellitus in which high blood glucose levels cause severe dehydration and an increase in serum osmolarity (relative concentration of solute); it is associated with a high risk of complications, including possible coma and death. It is related to diabetic ketoacidosis (dka), another complication of diabetes, but lacks the ketones of dka. ...Read more

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What is the treatment for hyperosmolar hyperglycemic state?

What is the treatment for hyperosmolar hyperglycemic state?

Insulin and fluids: Parentral adiminstration of Insulin is the key treatment. Such patients are dehydrated and have electrolyte imbalance, both of which are corrected with intravenous therapy. ...Read more

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What are the differences between diabetic ketoacidosis and a hyperosmolar hyperglycemic state?

What are the differences between diabetic ketoacidosis and a hyperosmolar hyperglycemic state?

Insulin and acidosis: Hi. DKA is an insulin deficient state that contrary to lay bias, occurs in both type 1's AND type 2's. The nonketotic hyperosmolar, hyperglycemic state is a condition that occurs in type 2's; they have enough insulin to prevent ketoacidosis but not enough to prevent profound hyperglycemia and hyperosmolarity. It takes FAR LESS insulin to prevent ketoacidosis than it does to prevent hyperglycemia. ...Read more

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Is abdominal pain a symptom of hyperosmolar hyperglycemic state?

Is abdominal pain a symptom of hyperosmolar hyperglycemic state?

Can be: But hyperosmolar hyperglycemic state is a medical emergency. If there is any consideration, check your blood sugar immediately and contact medical assistance of some sort. ...Read more

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What are the symptoms of hyperglycemic hyperosmolar nonketotic syndrome?

What are the symptoms of hyperglycemic hyperosmolar nonketotic syndrome?

Many: The most obvious sign of a hyperosmolar hyperglycemic state is an alteration in mental status or functioning. People may become lethargic or drowsy, confused, or even delirious. In severe cases a person may become unresponsive. Occasionally they can have seizures, visual problems, and movement or sensory problems. This is a dangerous condition that need immediate medical attention. ...Read more

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How's hyperosmolar hyperglycemic nonketotic coma treated?

How's hyperosmolar hyperglycemic nonketotic coma treated?

Insulin and fluid: Insulin and saline are administered intravenously and other medications added depending on the clinical findings and lab tests. ...Read more

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How is a hyperosmolar hyperglycemic nonketotic coma treated?

How is a hyperosmolar hyperglycemic nonketotic coma treated?

Coma: It should be treated in an intensive care unit (ICU) with close monitoring of the blood glucose and other electrolytes (salts) and treatment to slowly decrease the blood glucose. ...Read more

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What is hyperglycemic hyperosmolar nonketotic syndrome?

What is hyperglycemic hyperosmolar nonketotic syndrome?

Very high sugar: This occurs when the sugar gets very high, usually over 600. Because of the very high sugar the blood becomes very viscous, the patient is dehydrated and may become very lethargic or pass out. ...Read more

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What is a diabetic hyperglycemic hyperosmolar coma?

Dehydration: If you have type 2 diabetes that gets very out of control due to infection, stress, surgery, cortisone or other factors, you can become severely dehydrated as well as have a very high glucose. This can even lead to coma, with an up to 50% morbidity if not treated quickly and effectively with large amounts of IV fluids, a small amount of insulin, control of the original cause and adjustment of elec. ...Read more

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My friend is in a diabetic hyperglycemic hyperosmolar coma. What does this mean?

My friend is in a diabetic hyperglycemic hyperosmolar coma. What does this mean?

Coma due to diabetes: By your question i will assume he is in the hospital. This condition is due to poor control of diabetes either due to not taking medications or as a result of some inciting condition like infection amongst others, a better controll of diabetes will help prevent this. In summary it's a coma caused by caused by high glucose. ...Read more

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Can hyperosmolarity cause brain cells to shrink?

Can hyperosmolarity cause brain cells to shrink?

Yes: Mannitol is osmotic agent utilized to raised the serum osmolality and actually takes fluid from healthy neurons to make room for damaged neurons to swell. Another agent utilized in certain institutions is 3% nacl solution which again raises the serum osmolality for the same reason. Osmolarity is mol/kg and osmolality is mol/kg which is what is used in medicine. ...Read more

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What is a hyperosmolar coma?

What is a hyperosmolar coma?

Diabetic emergency: Hyperosmolar coma is a medical emergency seen in type ii diabetics when the blood sugar reaches extremely high levels, typically higher than 600 mg/dl. Often it is precipitated by a physiologic stress such as infection, myocardial infarction, stroke or other acute illness. The very high blood glucose may lead to disordered mental functioning with possible seizures then to coma and death. ...Read more

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If I am only hyperglycemic should I move onto insulin or continue taking metformin?

If I am only hyperglycemic should I move onto insulin or continue taking metformin?

Depends: Controlling blood sugars aggressively during pregnancy does have a positive impact on the baby. Generally the levels of blood glucose that we want in pregnancy are much lower than what is sought in nonpregnant individuals. Generally your fastings should be around 90 and your one hour post meal glucose should be under 140 at least but ideally lower. You need to move quickly to control your sugar. ...Read more

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How can you tell if you are hyperglycemic?

How can you tell if you are hyperglycemic?

Blood test: The only way to tell if your blood sugar is high is to have the blood tested. This can be done by a blood sample sent to a lab or by the use of a blood glucose monitor by someone familiar with its use. ...Read more

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What is a hyperosmolar nonketotic coma?

Endocrine emergencie: Honk or hyperosmolar nonketotic coma is when glucose levels rise above 4-500 and other electrolytes become grossly abnormal. This results in water loss and a very high concentration of solutes in the blood. (hyperosmolar component). The elevated glucose levels do not cause the production of ketones as happens in DKA and that is the non-ketotic component. This is a medical emergency. ...Read more

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