Doctor insights on:
What Can Cause Progressive Supranuclear Palsy
Tau protein D/O: No, tau protein deposits & neurofibrillary tangles in neurons cause the death of these cells. Because they are in some similar areas as parkinson's disease, psp can appear similar clinically, but there are clear differences. Treatment approaches are roughly the same with different areas needing most attention. Primarily balance/falls/injury, did inhibiting dementia & dysphagia/aspiration. ...Read moreSee 1 more doctor answer
...is a corruption of French "paralise" from Latinized Greek "paralysis." In the old days it meant any kind of persistent weakness. To this day Parkinson's disease is also called "paralysis agitans" which is a Latin translation of Dr. Parkinson's original name for it, the "shaking palsy." We've obviously reborrowed the full form "paralysis" into English as well; today ...Read more
Unlikely: Though anesthetics do have an effect on the brain, it is unlikely that they would cause this problem. The anesthetics that we use can decrease blood flow to certain areas of the brain, so they might unmask a pre-existing psp, but again that is speculation. I would talk to your neurologist about this problem. ...Read moreSee 1 more doctor answer
Good Rx Available!!!: Dopamine meds for physical parkinsonism: Azilect (mao-b selective inhibitor) & sinemet +/- Comtan (stalevo (carbidopa and levodopa and entacapone) is both together). Tailor rx & watch for side effects. Avoid Dopamine agonists (requip xl/mirapex er/neupro)--too side effect prone for psp patients. For dementia: namenda, paired with Exelon patch or aricept. For psychosis: seroquel or clozaril. Remember, response is variable, but worthwhile. ...Read moreSee 2 more doctor answers
Good History & exam!: Good history & exam are the keys. In expert hands, that is all you really need. However, a new test/imaging procedure called datscan can determine if the person is suffering from a true Dopamine degenerative state (parkinsonian sundrome) or not, it cannot destinguish b/w these parkinsonian syndromes, however! ...Read more
Supranuclear palsy is a rare brain condition that causes serious problems with walking, eye movements, and balance. The disorder develops slowly over time as the cells in parts of the brain that control movement are destroyed. Although there is no cure, there are ways ...Read more
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