Doctor insights on:
What Are The Risks Of Donating Bone Marrow
Life saving.: Benefit is not dying from the disease being treated with transplant. Risks are death from infection, or organ damage from treatment. Later on, risk is graft vs host disease (gvhd) where the new immune system attacks the recipient. Common sites are skin, mucus membranes, GI tract, liver. Infection also more likely with gvhd. Drugs can damage joints, esp. Hips and shoulders. Varies how severe. ...Read more
Bone marrow is the flexible tissue found in the interior of bones. In humans, red blood cells are produced in the heads of long bones, in a process known as hematopoesis. On average, bone marrow constitutes 4% of the total body mass of humans; in an adult weighing 65 kilograms (140 lb), bone marrow accounts for approximately ...Read more
Infection and pain: This is a relatively safe procedure but the marrow is harvested by taking a small amount from your hip bone. You lie on your stomach, the skin' muscle overlying the hip bone is anesthetized and cleaned. A needle is then inserted into the bone and gently rotated until it is deep enough to get to the marrow. A small amount is drawn out and the needle is removed. It is an outpatient procedure. ...Read moreSee 1 more doctor answer
There are many: The exact risks are dependent on the type of transplant chemotherapy or radiation given, who the donor is (self or somebody else) as well as how close the match is. There are some life threatening complications. There is a high infection risk, effects on the immune system and need for blood transfusions. Nausea, vomiting and fatigue are very common too. ...Read more
Under gen anesthesia: Donating bone marrow for transplantation entails a procedure called bone marrow harvesting. The donor is placed under general anesthesia and turned over to lie on his/her belly to expose the hip bones on the back. Multiple aspirations of bone marrow are collected (average about 1 liter) at adjacent sites on the hip bone on both sides until a particular number of cells are reached. ...Read more
Should i be nervous about donating bone marrow? I want to donate my bone marrow, but I'm nervous about the procedure. Will it be painful?
Somewhat: The idea is much worse than the event--but yes, it is somewhat painful. One of my most powerful recollections from medical training was the pediatric unit at md anderson center. Many of the kids there had to undergo repeated bone marrow tests--with great courage. So know that if you decide to go ahead, you will do something wonderful. If you just can't I am sure you will find other ways to help! ...Read more
PB vs BM: Most (but not all) stem cells for allogeneic stem cell transplants are donated from the peripheral blood. The risks of the "collection" are similar to any blood product donation. There may be risks of the drugs used before collection including potential chemotherapy or growth factor drugs. That is more detail than 400 characters allows. A bone marrow harvest requires multiple bone marrow biopsies. ...Read more
Stem cell collection: Some times stem cells for transplant can be collected from an IV in your arm. This process involves a medication, g-csf, which increases the stem cells. This medication can cause flu-like symptoms and bone pain. Then the cells are taken, similar to giving blood or platelets. ...Read moreSee 1 more doctor answer
Not long. : The process of becoming a donor is lengthy and very time-consuming. However, actually giving stem cells (or bone marrow) takes usually several hours. Marrow is collected in the or and takes 2-3 hours. Stem cells can also be taken from an IV like giving blood. But this may takes several hours. Thanks for considering marrow donation. ...Read more
Over 18 years: They prefer to take it from young adults up to the age of 45 years because the quality of stem cells is best in this age range. This can be extended up to 60 years among family members of the needy patient under special circumstances. ...Read more
See below: You have to be legal adult in order to give that up to someone else. ...Read more
No they do not: But they do check you and examine you to make sure that you are healthy and do not have any serious sickness, diseases or major health issues. ...Read more
Bone is a living growing tissue made mostly of collagen (protein that provides soft framework) & the mineral calcium phosphate that adds strength & hardens the framework. Two types of bone are found in the body; cortical (dense compact outer layer) & trabecular (makes up inner layer, ...Read more
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