Doctor insights on:
What Are The Risks Of Donating Bone Marrow
Stem cell collection: Some times stem cells for transplant can be collected from an IV in your arm. This process involves a medication, g-csf, which increases the stem cells. This medication can cause flu-like symptoms and bone pain. Then the cells are taken, similar to giving blood or platelets. ...Read moreSee 1 more doctor answer
Bone marrow is the flexible tissue found in the interior of bones. In humans, red blood cells are produced in the heads of long bones, in a process known as hematopoesis. On average, bone marrow constitutes 4% of the total body mass of humans; in an adult weighing 65 kilograms (140 lb), bone marrow accounts for approximately ...Read more
There are many: The exact risks are dependent on the type of transplant chemotherapy or radiation given, who the donor is (self or somebody else) as well as how close the match is. There are some life threatening complications. There is a high infection risk, effects on the immune system and need for blood transfusions. Nausea, vomiting and fatigue are very common too. ...Read more
Life saving.: Benefit is not dying from the disease being treated with transplant. Risks are death from infection, or organ damage from treatment. Later on, risk is graft vs host disease (gvhd) where the new immune system attacks the recipient. Common sites are skin, mucus membranes, GI tract, liver. Infection also more likely with gvhd. Drugs can damage joints, esp. Hips and shoulders. Varies how severe. ...Read more
Saves lives: Pros far outweigh the cons. You can save lives and provide an amazing gift to a very sick person by this selfless act of kindness. Minor chance of infection, and can be a little painful. ...Read more
Cure diseases: A bmt or stem cell transplant replaces a patient's bone marrow with that of someone else (allogeneic transplant) or by a patient's own marrow as a rescue from very high dose chemotherapy. With allogeneic transplant for cancers, the new bone marrow can attack and destroy cancer cells that it recognizes as bad, even though the patient's immune system failed to do that. ...Read moreSee 1 more doctor answer
Low complication : The potential complications from bone marrow biopsy include bleeding and infection. A physician who does the procedure often will have, usually, a low complication rate. In general the rate should be very low (my guess is less than 1%). Remember, the procedure gives information not otherwise obtainable. Discuss with you physician and if you need it- go for it. ...Read more
Many!: It depends on the type of transplant, whether autologous (self) or allogeneic (other). In general, risks are infection, bleeding, liver lung and kidney problems, infertility, cataracts, heart damage, nerve damage, and chronic immune system dysfunction. These risks can be fatal. ...Read moreSee 1 more doctor answer
Infection and pain: This is a relatively safe procedure but the marrow is harvested by taking a small amount from your hip bone. You lie on your stomach, the skin' muscle overlying the hip bone is anesthetized and cleaned. A needle is then inserted into the bone and gently rotated until it is deep enough to get to the marrow. A small amount is drawn out and the needle is removed. It is an outpatient procedure. ...Read moreSee 1 more doctor answer
Many possible: Possible side effects from a bone marrow transplant include: rejection of the donor marrow, graft vs. Host disease (donor cells attack the recipient), infections (bacterial, viral, fungal, etc...), mouth sores, stomach ulcers, diarrhea, liver disease, seizures, nerve pain, lung inflammation, hormonal deficiencies, osteoporosis, future cancers, etc... ...Read moreSee 1 more doctor answer
Bone marrow disease: The symptoms are related to the abnormality of the bone marrow function -i.e. Decrease production of the blood cell counts-or increase level of blood cells counts if something supresses bone marrow function-anemia, decrease WBC and platelet can happen. -symptoms will include fatigue, infection, fever, bleeding. If the cell count is too much-clots, fatigue, feeling sluggish can happen. ...Read more
Not many.: Local reactions at the phlebotomy site: bruise at the needle site — 23 percent sore arm — 10 percent hematoma at needle site — 2 percent sensory changes in the arm used for donation (eg, burning pain, numbness, tingling) — 1 percent systemic reactions: fatigue — 8 percent vasovagal symptoms — 5 percent nausea and vomiting — 1 percent. ...Read more
Save lives/norisk: A deceased donor is a true hero who may save multiple lives ((8 or 9 transplants from an ideal donor) and improve the quality of lives (through tissue donation) of many others. There are no risks since the person has already died. The funeral may be conducted with an open casket. What about including the words...." he/she was a hero" in a eulogy? ...Read moreSee 2 more doctor answers
Not sure: Cost vary for bone marrow transplantation, depending on the number of hospital days, number of ICU (intensive care unit) days, complications, rejection events, infections, etc... The bone marrow transplant team at each transplant center can give details of costs. A rough estimate would be a quarter million dollars or more. ...Read moreSee 1 more doctor answer
Depends on type: Bone tumors for the most part fall into primary and metastatic lesions. For the metastatic lesions of lung prognosis is poor. For breast Ca there are long term survivals. Of the primary lesions there are benign and malignant lesions. The benign like enchondromas grow slowly and may have some pain. The malignant lesions such as osteo and chondrosarcomas can destroy the bone and metastasize . ...Read moreSee 1 more doctor answer
It is a bit complica: You will be given an IV infusion of stem cells, just like taking a blood transfusion. The stem cells can be taken from the bone marrow or from the peripheral blood. But there is a preparatory phase of giving chemotherapy and radiotherapy wwhich is called conditioning regimen, often given a few days ahead of infusing the stem cells. ...Read more
Bone is a living growing tissue made mostly of collagen (protein that provides soft framework) & the mineral calcium phosphate that adds strength & hardens the framework. Two types of bone are found in the body; cortical (dense compact outer layer) & trabecular (makes up inner layer, ...Read more
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