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Doctor insights on: What Are The Most Common Complications Of Scid

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What are the most common complications of scid?

What are the most common complications of scid?

Infection: Life threatening infections, which can cause death. See an immunodeficiency specialist if you know a child with scid that has not been fully evaluated by an expert in this area. ...Read more

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Dr. David Rosenthal
138 doctors shared insights

Severe Combined Immunodeficiency (Definition)

Severe combined immunodeficiency is a group of inherited conditions that result in severe abnormalities of the immune system. It usually causes one or more serious infections in newborns that ...Read more


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Is scid communicable?

Is scid communicable?

No: Severe combined immunodeficiency (scid) is a genetic abnormality with the immune system. It is, therefore, not infectious (or communicable) to others. Scid patients, however, are highly susceptible to any infectious disease including those that would not usually cause disease in people with normal immune systems. ...Read more

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What are the signs of SCID?

What are the signs of SCID?

Serious infections: SCID is an immune deficiency present at birth. MDs think about this when infants have several serious illness early on. Texas tests for this on their newborn screens to help in early detection. This article may help answer more of your questions. http://www.scid.net/ ...Read more

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How long could someone with scid live?

Depends: Depends on which type of scid they have and more importantly when they are diagnosed and treatment begun. The earlier the recognition is, the less complications and infections the infant will have and the better the outcome. ...Read more

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How long will someone survive with scid?

How long will someone survive with scid?

Depends on treatment: Without treatment, an infant with scid will not survive more than a couple of years after birth. Treatment with bone marrow transplantation, enzyme replacement, or gene therapy can potentially lead to a normal life span. However, outcomes are best if treatment is started early, before the infant develops infections. Even in the best case, regular follow up with an immunologist is suggested. ...Read more

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Can you tell me everything to know about scid.?

Early Diagnosis: Severe Combined Immunodeficiency (SCID) is a genetic disorder causing severe dysfunction of the immune response to infections (bacteria, viruses, and fungi). Several disease variants occur and symptoms can differ however most children die during their first 2 yrs from infection without treatment. Bone marrow transplant is curative. Early diagnosis and treatment are key to survival. ...Read more

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What kind of inheritance pattern does scid have?

What kind of inheritance pattern does scid have?

Autosmal recessive: The genetic forms of severe combined immunodeficiency are caused by enzyme deficiencies, with affected individuals having two abnormal genes at the enzyme locus. Parents will have one normal and one abnormal gene with 50% enzyme activity (enough to produce immune cells). Parents will have a 25% risk for scid with each future pregnancy. ...Read more

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Is scid a problem with the chromosomes?

Yes: There are several different problems with chromosomes that lead to severe combined immunodeficiency disease (scid). ...Read more

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What kind of mutation occurs in scid disease?

What kind of mutation occurs in scid disease?

Depends: There are too many different types of scid - severe combined immunodeficiency for there to be just one mutation. Scid is commonly referred to as "bubble boy" disease in the lay press. The most common type is linked to the x chromosome and causes a defect in t cells and natural killer cells. ...Read more

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Are there any causes besides genetics of developing scid?

SCID: None that have been discovered unless the newborn had a serious or severe cancer/leukemia requiring chemotherapy and radiation which wipes out the immune system. Additionally, certain diseases (itp, etc.) that require strong therapy (rituxan) can wipe out the immune system. ...Read more

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