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Doctor insights on: What Are The Latest Treatments On Triple Negative Breast Cancer

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What are the latest treatments on triple negative breast cancer?

What are the latest treatments on triple negative breast cancer?

Chemotherapy: Triple negative implies the absence of estrogen and Progesterone receptors, as well as the absence of overexpression of the her-2 gene. Because of this, endocrine manipulation (tamoxifen, arimidex, etc. Doesn't work, nor does herceptin (trastuzumab). In addition to surgery (and sometimes radiotherapy), most triple negative patients receive combination chemotherapy. ...Read more

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Dr. Barry Rosen
4,344 doctors shared insights

Cancer (Definition)

Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more


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What are the latest treatments and/or cures for breast cancer?

What are the latest treatments and/or cures for breast cancer?

Many: Breast cancer has good treatments available which have been around for the past 30+ years. With current treatments(there are many medicines besides surgery and radiotherapy) the cure rates are over 80%. Just go to a good oncologist and seek the details you want to know about. ...Read more

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What are the best treatments for late stage lung cancer based on pathology type?

What are the best treatments for late stage lung cancer based on pathology type?

Chemotherapy: Whatever the type of malignancy, late stage, i.e. Stage iv, suggests the tumor has gone beyond local control and cannot be treated effectively except with chemotherapy, commonly platinum-based. However, this does not preclude surgery or radiorx which may limit "tumor-burden" and relieve some symptoms. Chemotherapy is ideal for small-cell carcinoma. ...Read more

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What are the two significant but different treatments for breast cancer?

What are the two significant but different treatments for breast cancer?

Likely lump va mrm: It sounds as if u r asking about breast conservation therapy versus mastectomy. If caught early with few or no lymph nodes involved then either a mastectomy or lumpectomy+breast radiation have equal cure rates. Chemotherapy can be given for the same reasons with either approach. Cure rates r the same with either. The difference is whether or not the natural breast is kept or reconstruction reqd. ...Read more

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What is the prognosis for triple negative breast cancer?

What is the prognosis for triple negative breast cancer?

Need more info...: All else being equal, women with triple negative breast cancer have a worse prognosis than those who are receptor-positive; however, prognosis is highly correlated with the size of the cancer and the presence of cancer within the axillary lymph nodes. Furthermore, some women are more responsive to chemo than others, which will affect prognosis. ...Read more

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What are the triple positive breast cancer survival rates?

What are the triple positive breast cancer survival rates?

Depends: Other factors such as stage can contribute to survival rates. Please discuss this with your doctor in context of all the other factors that can contribute to survival rates here is a good review of breast cancer http://www.Cancer.Net/cancer-types/breast-cancer. ...Read more

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What are the benefits of screening early for breast cancer?

What are the benefits of screening early for breast cancer?

Early detection: The earlier breast cancers are caught, the more likely they can be cured. Screening mammograms starting at age 40 can save 1 life for every 450-1000 mammograms done (depending on the study.) screening detects breast cancer at an early stage. ...Read more

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What are the tests for breast carcinoma?

What are the tests for breast carcinoma?

Mammogram/ultrasound: The main tests used to evaluate for breast cancer are digital mammograms and breast ultrasound. If there is any abnormality or palpable lump, a core or fine needle biopsy is performed. Other tests used to help: mri, bsgi, pem. Your physician and radiologist will determine which tests are best for each individual. ...Read more

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What are the tests for metastatic breast cancer?

What are the tests for metastatic breast cancer?

PET/CT: The primary test for staging for breast cancer is the pet/ct scan. A bone scan is also helpful if you're concerned about bony disease, and a head MRI for brain metastases. The sites of distant spread for breast cancer are generally the lungs, the liver, the bone and the brain, so these tests are sufficient. ...Read more

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What is the likelihood of pregnancy after radiation therapy on breast cancer?

Same as without : Radiation for breast cancer is delivered to the breast. This should not affect the chances of pregnancy. ...Read more

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What are financial implications of using herceptin (trastuzumab) as a breast cancer treatment?

What are financial implications of using herceptin (trastuzumab) as a breast cancer treatment?

?: I have never had an issue of trastuzumab (herceptin) coverage in appropriate patients. Individual co-pays are based on each patients insurance. There may be a benefit of trastuzumab in 0/low expression breast cancer that is the subject of a cooperative group clinical trial -- nsabp b-47 - clinicaltrials.Gov id: nct01275677. ...Read more

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What is the risk of having multifocal carcinoid tumors in stomach and duodenal type-1 and what is the latest news about available treatments?

What is the risk of having multifocal carcinoid tumors in stomach and duodenal type-1 and what is the latest news about available treatments?

REcurrence: Type i gastric carcinoids are the most common and usually do not metastasize. They require careful surveillance with endoscopic resection for the smaller lesions and antrectomy for multifocal and larger recurrences. Reduction of gastrin levels felt to be helpful. ...Read more

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What are the side-effects of breast cancer treatment?

What are the side-effects of breast cancer treatment?

Depends on treatment: This is a complex question. Each treatment-surgery, radiation, chemo, hormonal- has it's own uniques set of side effects. In addition, not everyone will experience side effects. The good news is that most side effects can be managed with treatment or medications. Be sure to ask your oncology team questions. ...Read more

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Pl explain ER pr cerbb2 all shows negative , besides not responding to oral treatment, what other significance of this test for breast cancer?

Pl explain ER pr cerbb2 all shows negative , besides not responding to oral treatment, what other significance of this test for breast cancer?

More complex Rx: Er, pr, erbb2 negative is also known as triple negative, estrogen receptor, Progesterone receptor and epidermal growth factor receptor (also known as her2) negative breast cancer (bc) and represents 20-25% of all bc. In general, these bc are more difficult to treat and require more aggressive treatment including platinum based chemo. The most important prognostic feature of any bc is stage. ...Read more

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What is the risk of biopsy on prostate? What are different methods of biopsy?

What is the risk of biopsy on prostate? What are different methods of biopsy?

Infection: Infection is the biggest risk. Bleeding and swelling can occur leading to trouble urinating. Most are done in urologist office while awake and there can sometimes be pain. Few patients are done under anesthesia based on patients health. Transrectal is how most biopsies are accomplished. ...Read more

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Are there negative effects of breast cancer treatment/ mammography after a year? What should I expect?

Mammo is low risk: Treatment effects can vary significantly depending on what is done (type of surgery, radiation, chemo). Mammography should not have any significant effects, especially after one year. Mammograms are low dose radiation, but any radiation can increase cancer risk over the long term (decades). The cancer risk from mammograms is extremely low. Note that you are below the recommended screening age. ...Read more

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What are the benefits we get from zometa and what are the side effect? I'm a her2 breast cancer stage 3 patient

Controversial: I personally think there is a benefit based on the trials. Specifically in post-menopausal women. Not only treating or preventing osteoporosis but also preventing breast cancer recurrence. But i think the final answer is still unknown. The side effects are few but one which is rare can be problematic, osteonecrosis of the jaw. ...Read more

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Dr. Barry Rosen
1,378 doctors shared insights

Breast Cancer (Definition)

Occurs when glandular cells lining the milk ducts and lobules of the human breast begin to grow in an unregulated manner. Often curable if found early and treated effectively with surgery, hormonal therapy, chemotherapy and targeted therapy, or a combination thereof. Early detection before the malignancy becomes large enough to be felt depends on mammography/sonography and MRI imaging of the breast ...Read more


Dr. Mark Hoepfner
1,061 doctors shared insights

Breast Carcinoma (Definition)

Most breast cancers are carcinomas. This is a type of breast cancer. These cancers start in the cells that line organs and tissues. In fact, breast cancers are often a type of carcinoma called adenocarcinoma, which starts in cells that make glands (glandular tissue). Breast adenocarcinomas start in the ducts (the milk ducts) or ...Read more