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Doctor insights on: What Are The Latest Treatments On Triple Negative Breast Cancer

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What are the latest treatments on triple negative breast cancer?

What are the latest treatments on triple negative breast cancer?

Chemotherapy: Triple negative implies the absence of estrogen and Progesterone receptors, as well as the absence of overexpression of the her-2 gene. Because of this, endocrine manipulation (tamoxifen, arimidex, etc. Doesn't work, nor does herceptin (trastuzumab). In addition to surgery (and sometimes radiotherapy), most triple negative patients receive combination chemotherapy. ...Read more

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Dr. Barry Rosen
1,336 doctors shared insights

Breast Cancer (Female) (Definition)

Breast cancer results when glandular cells lining the milk ducts and lobules of the human breast begin to grow in an unregulated manner. The growth occurs initially inside the ducts but eventually breaks outside into the breast tissue and ultimately spreads both to the lymph nodes in the armpit and via the bloodstream to other parts of the body. Because of the promoting affect of estrogen almost all breast cancer occurs in women and is a rarity in men. The unregulated growth is due to both inherited and acquired genetic defects. It is the most common malignancy in women but it often curable if found early and treated effectively with surgery, hormonal therapy, chemotherapy and targeted therapy, or a combination thereof. Early detection before the malignancy becomes large enough to be felt depends on mammography/sonography and MRI imaging of the breast on an annual basis. ...Read more


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Is there a safe treatment for heavy periods after triple negative breast cancer. Am not on any medication or contraception.

Is there a safe treatment for heavy periods after triple negative breast cancer. Am not on any medication or contraception.

Probably but...: .....You are very young and had a triple negative breast cancer. I do not know about uk standards for brca testing but you could carry a brca mutation (especially brca1). If so, preventative hysterectomy with ovarian surgery would be a consideration and that would take care of your problem. Discuss it with your doc. Best to you. ...Read more

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Need expert advice on any information on treatment for triple negative stage 4 breast cancer?

Need expert advice on any information on treatment for triple negative stage 4 breast cancer?

Medical Oncology: Triple negative is a more aggressive form of breast cancer, especially in younger women. It can be difficult (though not impossible) to treat. I recommend consulting with your medical oncologist for options. You may want to get a 2nd opinion at a university hospital for clinical trials. Here is a good site: http://www.Tnbcfoundation.Org/ keep positive and follow through with treatments. ...Read more

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I have triple negative stage 3 breast cancer. Ac followed by t. Neulasta (pegfilgrastim) for ac....Is it routine to continue neulasta (pegfilgrastim) for t treatments?

I have triple negative stage 3 breast cancer. Ac followed by t. Neulasta (pegfilgrastim) for ac....Is it routine to continue neulasta (pegfilgrastim) for t treatments?

Neulasta (pegfilgrastim): For ac regimen dose dense (every 2 weeks, we recommend neulasta). After that i usually give Taxol (also called paclitaxel) weekly x 12 weeks and Neulasta (pegfilgrastim) is not used for weekly regimen. Some oncologists prefer Taxol every 3 weeks x 4 doses (big dose taxol), than it can be used. Weekly regimen have robust data and is well tolerated and we can avoid side effects of Neulasta (pegfilgrastim) (which can be rough). ...Read more

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Is it normal to have long heavy periods (11 day) after treatment for breast cancer. I don't take any medication as i was triple negative. ?

No: Long, heavy periods can occur at any time but it is not normal after treatment for breast cancer. If you received chemo for your triple neg cancer then periods usually go away. Heavy bleeding means you need to see your gynecologist for evaluation. ...Read more

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Survival rate for triple neg receptors for early stage breast cancer after chemo treatment? No lymph nodes involve, stage 1b, grade 2, mastec done

Survival rate for triple neg receptors for early stage breast cancer after chemo treatment?  No lymph nodes involve, stage 1b, grade 2, mastec done

Excellent: According to adjuvant online (www.Adjuvantonline.Com), you have about an 82% 10 yr survival rate based on your specific information provided. This is only an estimate since there are details I do not have such as type of chemotherapy being used. For triple negative breast cancer, these survival rates are quite excellent. ...Read more

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Hello, my mum lost her sense of smell due to chemo/radiation for triple neg breast cancer, will it ever come back? its been almost a year since she has finished chemo and 9 months since she finished radiation therapy. she is 54 years old. Thank you

Hello, my mum lost her sense of smell due to chemo/radiation for triple neg breast cancer, will it ever come back? its been almost a year since she has finished chemo and 9 months since she finished radiation therapy. she is 54 years old. Thank you

Possible: If it is going to come back, we will know in the next 6-12 months. Nerves heal slowly, and when they heal, it can take a long time. Since this was a problem for a long time, it may not come back at this point. It is worth being patient. Are we certain it is due to the treatments? Sometimes a person may lose their sense of smell for other reasons. ...Read more

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Are there negative effects of breast cancer treatment/ mammography after a year? What should I expect?

Are there negative effects of breast cancer treatment/ mammography after a year? What should I expect?

Mammo is low risk: Treatment effects can vary significantly depending on what is done (type of surgery, radiation, chemo). Mammography should not have any significant effects, especially after one year. Mammograms are low dose radiation, but any radiation can increase cancer risk over the long term (decades). The cancer risk from mammograms is extremely low. Note that you are below the recommended screening age. ...Read more

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Pl explain ER pr cerbb2 all shows negative , besides not responding to oral treatment, what other significance of this test for breast cancer?

More complex Rx: Er, pr, erbb2 negative is also known as triple negative, estrogen receptor, Progesterone receptor and epidermal growth factor receptor (also known as her2) negative breast cancer (bc) and represents 20-25% of all bc. In general, these bc are more difficult to treat and require more aggressive treatment including platinum based chemo. The most important prognostic feature of any bc is stage. ...Read more

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What is the best treatment for s tage 2a breast cancer in a 63 yo male. No nodes were positive and pet CT scan was negative. Er positive.?

What is the  best treatment  for s tage  2a  breast  cancer in a  63  yo male. No nodes  were positive and pet CT  scan was negative. Er  positive.?

Tamoxifen: After a mastectomy, use of tamoxifen in an er+ tumor has the best historical experience for this rare condition in men. The decision to use chemotherapy may depend on comparable metrics used for breast cancer in women such as size of tumor, grade, presence of markers (her2neu, high ki- 67). Though no data in men, oncotype DX theoretically can help with treatment decision about need for chemo. ...Read more

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Dr. Barry Rosen
4,214 doctors shared insights

Cancer (Definition)

Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more


Dr. Mark Hoepfner
1,028 doctors shared insights

Breast Carcinoma (Definition)

Breast carcinoma is a type of cancer where this uncontrolled growth of breast cells. Symptoms can include breast lumps, pain, and weight ...Read more