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Doctor insights on: What Are The Effects Of Methotrexate And Coumadin

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What side effects are associated with Trexall (methotrexate)?

Trexall (methotrexate): See: http://www.drugs.com/sfx/trexall-side-effects.html

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Methotrexate (Definition)

Methotrexate was originally used in the early 1950's as a treatment for cancer but was also found to be effective in many other diseases including rheumatoid arthritis and psoriasis. It has anti inflammatory and immunosuppressive properties which make it an excellent first line therapy for RA ...Read more


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Are there any long term effects for a 6y/o to take 22.5mg of methotrexate for jra for long term? Also please list any side effects

Are there any long term effects for a 6y/o to take 22.5mg of methotrexate for jra for long term? Also please list any side effects

Unfortunately: This is regarded as standard treatment but jra is a disease that actually responds to nutlritional treatment. First stop all forms of sugar and sweeteners and look up acam@acam.Org for a physician who uses nutrients in his/her practice. ...Read more

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What would happen if one took methotrexate injections weekly and their immune system was not overactive? Would they feel sick or have side effects?

What would happen if one took methotrexate injections weekly and their immune system was not overactive? Would they feel sick or have side effects?

Yes: In many patients yes in many patients know it is a liver toxin which causes fibrosis of the liver with long-term use . This has to be monitored all during the drug usage every six months. ...Read more

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Is 22mg of methotrexate injections a high dose or just high for a 6 y/0 with jra to start off with? Please list possibly side effects at this dosage?

Is 22mg of methotrexate injections a high dose or just high for a 6 y/0 with jra to start off with? Please list possibly side effects at this dosage?

Toward high...: While there are variables-size and weight; severity of the condition- i start most adults on this dose and children 15-20mg. But one cannot really say. Certainly for the short term i would not expect issues. One question i would ask: did the medicine get started by a rheumatologist or pediatric rheumatologist! ...Read more

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Do you have information on methotrexate uses and effects?

Do you have information on methotrexate uses and effects?

Many and quite safe!: Mtx is used in many autoimmune diseases with great effect. The drug is given IV in high doses to treat cancer. In much lower doses, given subcutaneously like insulin, with fewer side-effects than the same oral dose, does not go to the liver. And you absorb 100%, not the 40-90% when taken by mouth. Great drug. Ist line in ra! ...Read more

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Any methotrexate side effects?

Any methotrexate side effects?

Plenty : XX oral dos: Methotrexate is a surprisingly effective drug for many forms of arthritis and the consensus 1st choice for RA by the acr and eular (european). The oral dosage is more problematic because of variable absorption and first-pass effect through liver. It is completely absorbed with sucutaneous injection and doesn't bolus liver. Hair loss can be a problem. Everyone should take 2mg of folic acid. ...Read more

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Common side effects of coumadin (warfarin)?

Common side effects of coumadin (warfarin)?

Bleeding. : This medication can cause serious bleeding if it affects your blood clotting proteins too much (shown by unusually high inr lab results). Even if your doctor stops your medication, this risk of bleeding can continue for up to a week. Tell your doctor right away if you have any signs of serious bleeding, including: unusual pain/swelling/discomfort/easy bruising, prolonged bleeding from cuts. ...Read more

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Possible side effects of coumadin (warfarin)?

Bruising, bleeding: The most common side effects of Coumadin (warfarin) are bruising and bleeding. Coumadin (warfarin) affects other medicines and can make them work more or less well than normal. Coumadin (warfarin) can also increase the side effects caused by other drugs. You have to be careful about what you eat with Coumadin (warfarin) and make sure you aren't getting too much vitamin k in your diet since it can counteract the effectiveness of coumadin, (warfarin) . ...Read more

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What are the side effects of coumadin (warfarin)?

What are the side effects of coumadin (warfarin)?

Bleeding: Coumadin (warfarin) is a potent blood thinner si most common & dangerous side effect is bleeding which is why INR levels must be closely monitored. Increased bruising is often seen & expected. ...Read more

Warfarin (Definition)

Warfarin is a medication used to thin the blood and to prevent or treat people with blood clots. It requires frequent blood ...Read more


Dr. Ted King
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Coumadin (Definition)

Coumadin is an anticholinergic agent which is a kind of anti-Parkinson's drug ...Read more