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What Are The Effects Of Methotrexate And Coumadin
Trexall (methotrexate): See: http://www.drugs.com/sfx/trexall-side-effects.htmlGet a more detailed answer ›
Methotrexate was originally used in the early 1950's as a treatment for cancer but was also found to be effective in many other diseases including rheumatoid arthritis and psoriasis. It has anti inflammatory and immunosuppressive properties which make it an excellent first line therapy for RA ...Read more
Are there any long term effects for a 6y/o to take 22.5mg of methotrexate for jra for long term? Also please list any side effects
What would happen if one took methotrexate injections weekly and their immune system was not overactive? Would they feel sick or have side effects?
Yes: In many patients yes in many patients know it is a liver toxin which causes fibrosis of the liver with long-term use . This has to be monitored all during the drug usage every six months. ...Read more
Is 22mg of methotrexate injections a high dose or just high for a 6 y/0 with jra to start off with? Please list possibly side effects at this dosage?
Toward high...: While there are variables-size and weight; severity of the condition- i start most adults on this dose and children 15-20mg. But one cannot really say. Certainly for the short term i would not expect issues. One question i would ask: did the medicine get started by a rheumatologist or pediatric rheumatologist! ...Read more
Many and quite safe!: Mtx is used in many autoimmune diseases with great effect. The drug is given IV in high doses to treat cancer. In much lower doses, given subcutaneously like insulin, with fewer side-effects than the same oral dose, does not go to the liver. And you absorb 100%, not the 40-90% when taken by mouth. Great drug. Ist line in ra! ...Read moreSee 1 more doctor answer
Plenty : XX oral dos: Methotrexate is a surprisingly effective drug for many forms of arthritis and the consensus 1st choice for RA by the acr and eular (european). The oral dosage is more problematic because of variable absorption and first-pass effect through liver. It is completely absorbed with sucutaneous injection and doesn't bolus liver. Hair loss can be a problem. Everyone should take 2mg of folic acid. ...Read more
Bleeding. : This medication can cause serious bleeding if it affects your blood clotting proteins too much (shown by unusually high inr lab results). Even if your doctor stops your medication, this risk of bleeding can continue for up to a week. Tell your doctor right away if you have any signs of serious bleeding, including: unusual pain/swelling/discomfort/easy bruising, prolonged bleeding from cuts. ...Read moreSee 1 more doctor answer
Bruising, bleeding: The most common side effects of Coumadin (warfarin) are bruising and bleeding. Coumadin (warfarin) affects other medicines and can make them work more or less well than normal. Coumadin (warfarin) can also increase the side effects caused by other drugs. You have to be careful about what you eat with Coumadin (warfarin) and make sure you aren't getting too much vitamin k in your diet since it can counteract the effectiveness of coumadin, (warfarin) . ...Read more
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