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Doctor insights on: What Are The Differences Between Claritin And Clarinex

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Dr. Stephen Kimura Dr. Kimura
Internal Medicine - Allergy & Immunology
31 years in practice
University of Kansas School of Medicine
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What are the differences between Claritin (loratadine) and clarinex?

What are the differences between Claritin (loratadine) and clarinex?

Metabolite: Clarinex (desloratadine) is des-loratadine and Claritin is loratadine. Clarinex (desloratadine) is the active metabolite of claritn. So (according to the manufacturer) you have the benefits of loratidine with minimal side effects. It is common in the pharmaceutical industry to use active metabolites or isomers of drugs. This potentially gives you a more active compound while minimizing the potential side effect. ...Read more

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Dr. Ashraf Abdel Azeem
526 doctors shared insights

Claritin (Definition)

Claritin is a non-sedating antihistamine which is a kind of antihistamine type drug (common ...Read more


Dr. Paul Carter Dr. Carter
Internal Medicine - Allergy & Immunology
26 years in practice
East Tennessee State University James H. Quillen College of Medicine
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What are the differences between loratadine, desloratidine?

What are the differences between loratadine, desloratidine?

Similar: Desloratidine is the active metabolite of loratidine. Loratidine is available as Claritin (loratadine) and must be metabolized to desloratidine in the liver to become the active metabolite desloratidine. However, desloratidine is available as Clarinex and is already in the more potent form. ...Read more

Dr. Dareen Siri faaaai facaai fisaai Dr. Siri faaaai facaai fisaai
Internal Medicine - Allergy & Immunology
17 years in practice
UC San Diego School of Medicine
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I was wondering what are the differences between loratadine and desloratidine?

I was wondering what are the differences between loratadine and desloratidine?

Des/loratadine: Desloratadine is the primary metabolite is loratadine. The advantage is thought to be quicker onset of action and longer action of anti-histamine effect. There is a small percentage of patients in which neither drug is able to be metabolized adequately. At usual doses, both are considered non-sedating specific h1 antagonists. Clinically speaking both are useful drugs for typical allergies. ...Read more

Dr. Bennett Werner Dr. Werner
Internal Medicine - Cardiology
40 years in practice
University of Maryland School of Medicine
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What are the differences between loratadine and desloratidine in how well it works or how long it lasts?

What are the differences between loratadine and desloratidine in how well it works or how long it lasts?

Take one, get both: When you take loratidine, your liver breaks it down to desloratine which is actually responsible for the anti-histamine effects you need. Desloratidine has a much longer effect (28 hours) than loratidine (8 hours) which is why loratidine lasts such a long time. ...Read more

Dr. Steven Cohen Dr. Cohen
Internal Medicine - Allergy
45 years in practice
The Ohio State University College of Medicine
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What is the difference between clarinex and claritin (loratadine)?

What is the difference between clarinex and claritin (loratadine)?

Structure: Clarinex is one stereo chemical form of the loratidine molecule. It has a longer duration of action, 27 hours, than claritin, (loratadine) and is a truly a once daily medication. ...Read more

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Dr. Thomas Josa Dr. Josa
Internal Medicine - Allergy & Immunology
35 years in practice
University of Copenhagen Faculty of Medicine
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What is the difference between loratadine and desloratidine?

Almost identical: Despite claims, in practice Not much. Just a minor modification of the molecule as one is a metabolic derivative of the other. The efficacy is about the same. ...Read more

Dr. John Klimas Dr. Klimas
Internal Medicine - Allergy & Immunology
44 years in practice
University at Buffalo, The State University of New York School of Medicine & Biomedical Sciences
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Can I use Claritin (loratadine) as a substitute for clarinex?

Yes: Clarinex (desloratadine) has only slight differences in chemical structure from the original product of Claritin and in my clinical experience you will not notice any difference in relieving your allergy symptoms. The generic of claritin, loratadine, is also much less expensive and is available at most drug stores. ...Read more

Dr. John Overholt Dr. Overholt
Internal Medicine - Allergy & Immunology
22 years in practice
East Tennessee State University James H. Quillen College of Medicine
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In terms of molecular content, is Claritin (loratadine) any different from clarinex?

Yes: Clarinex is desloratidine, the major metabolite of loratidine or claritin (loratadine). So, when you take loratidine, the body turns much of it into desloratidine. Clinically, there is not much difference between the two. ...Read more

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Dr. Stevan Cordas Dr. Cordas
Internal Medicine
53 years in practice
Philadelphia College of Osteopathic Medicine
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I see there is no way to cure eczema, but how much do antihistamines like claritin, (loratadine) clarinex, or zyrtec help prevent eczema?

Eczema - cure: Eczema can go away if it is caused by something like a food or chemical but it requires a thorough investigation by a allergist or dermatologist. Some hereditary forms cannot be cured but only controlled by medications. Antihistamines help to reduce itching but cannot cure this condition. ...Read more

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Dr. Charlene Sojico Dr. Sojico
Pediatrics
37 years in practice
University of the East, Ramon Magsaysay Memorial Medical Center
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Zyrtec, claritin, (loratadine) allegra, clarinex. Other allergy pill options? Year-round, persistant allergies. Wet in ears, post-nasal drip (sore throat).

Zyrtec, claritin, (loratadine) allegra, clarinex. Other allergy pill options? Year-round, persistant allergies. Wet in ears, post-nasal drip (sore throat).

Before you go : Looking for another allergy medication, i would keep the one that works best for you and take it diligently everyday with a steroid nasal spray twice daily for a month to see a big difference with just burst of meds here and there and only when you feel like it. If you have already done this, then it is time to see your doctor, possibly referral to allergist or ENT depends on what the problem is. ...Read more

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Dr. James Ferguson Dr. Ferguson
Pediatrics
42 years in practice
University of Texas Medical Branch School of Medicine
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What are the differences between zytrec and Claritin (loratadine) in effectiveness?

Individual issue: There is only one way to tell, trial & error.Both are helpful for many.Zyrtec has a benedryl like quality in that it crosses into the brain & can cause some sedation, while Claritin (loratadine) does not.In some small infants, their problem is less allergy and more irritant based (smoke, fumes, dust etc) and neither will help with irritants. ...Read more

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Dr. Douglas Fronzaglia Dr. Fronzaglia
Internal Medicine - Geriatrics
17 years in practice
Lake Erie College of Osteopathic Medicine
12
Dr. Stuart Kanter Dr. Kanter
Internal Medicine - Geriatrics
17 years in practice
Midwestern University Chicago College of Osteopathic Medicine
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Difference between loratadine and benadryl (diphenhydramine)?

Difference between loratadine and benadryl (diphenhydramine)?

Different drug class: Although both are antihistamines, they are different chemicals. Benadryl (diphenhydramine) is sedating. Loratadine is not. ...Read more

Dr. Samuel Gubernick Dr. Gubernick
Internal Medicine - Allergy & Immunology
30 years in practice
Nova Southeastern University College of Osteopathic Medicine
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Dr. Diane Minich Dr. Minich
Family Medicine
33 years in practice
University of Toledo College of Medicine
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What is the difference between loratadine and benadryl (diphenhydramine)?

What is the difference between loratadine and benadryl (diphenhydramine)?

Different antihistam: Both are antihistamines. Benadryl (diphenhydramine) is a sedating shorter acting antihistamine and Loratadine is a longer acting non sedating antihistamine. ...Read more

Dr. Lily Hwang Dr. Hwang
Pediatrics - Allergy & Asthma
14 years in practice
Ross University School of Medicine
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What is the difference between zyrtec and Claritin (loratadine) medicines?

Yes : Similarity: in the 2nd generation antihistamine class of drugs. Zyrtec and Claritin (loratadine) are safe in pregnancy. Both can cause dryness and urinary symptoms as a sideffect differences: Claritin (loratadine) does not usually cause drowsiness. Zyrtec typically can. The time it takes to be effective vary as well. As far as effectiveness: depends on person. Zyrtec in some studies have been shown to be faster acting. ...Read more

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Dr. John Overholt Dr. Overholt
Internal Medicine - Allergy & Immunology
22 years in practice
East Tennessee State University James H. Quillen College of Medicine
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What is the difference between loratadine and cetirizine dihydrochloride? Is one better?

What is the difference between loratadine and cetirizine dihydrochloride?  Is one better?

Cetirizine FTW: Most allergists would recommend cetirizine. It is more effective at controlling symptoms than loratidine. Cetirizine does make 10-15% of people sleepy, however. ...Read more

Dr. Bennett Werner Dr. Werner
Internal Medicine - Cardiology
40 years in practice
University of Maryland School of Medicine
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What is the difference between desloratidine and loratidine? Is one better than the other?

What is the difference between desloratidine and loratidine?  Is one better than the other?

Take one, get both: When you take loratidine, your liver breaks it down to desloratine which is actually responsible for the anti-histamine effects you need. Desloratidine has a much longer effect (28 hours) than loratidine (8 hours) which is why loratidine lasts such a long time. ...Read more

Dr. Anifat Balogun Dr. Balogun
ENT - Head & Neck Surgery
25 years in practice
Hahnemann Medical College
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What is the difference between Claritin (loratadine) and meclizine?

Claritin (loratadine) vs Meclizin: Both are antihistamines. Claritin (loratadine) is 2nd generation, used for control of symptoms of allergic rhinitis and Meclizine is 1st generation used to control nausea and vomiting during motion sickness and vertigo. ...Read more

Dr. John Overholt Dr. Overholt
Internal Medicine - Allergy & Immunology
22 years in practice
East Tennessee State University James H. Quillen College of Medicine
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Is there a difference between alegra and zyrtec and claritin (loratadine)?

Is there a difference between alegra and zyrtec and claritin (loratadine)?

Most allergists: Would recommend zyrtec and Allegra over claritin (loratadine). Zyrtec makes a few people sleepy, but may be slightly stronger than allegra. ...Read more

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Dr. Tanya Russo
35 doctors shared insights

Desloratidine (Definition)

Desloratidine is a low strength steroid which is a kind of ...Read more


Dr. Julie Abbott
43 doctors shared insights

Clarinex (Definition)

Clarinex is a low strength steroid which is a kind of ...Read more