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What Are The Differences Between A Bone Marrow Biopsy And Aspiration
A bone marrow biopsy is taken from the pelvic bone. A coring needle is advanced into the bone, which allows one to extract a sliver of the bone marrow, the red part of the bone. It is cut and viewed under a microscope. A bone marrow aspirate, obtained with a syringe, is usually bone at the same time. These are done to diagnose blood problems or to check for tumors in ...Read more
Depends on purpose: How many tests can be done from blood? Millions. How many tests can be done from a bone marrow biopsy (BMB) specimen? Many? What tests should be done? It depends on 1) purpose for performing the BMB and 2) the findings the pathologist sees on morphologic examination of the aspirate & biopsy. Tests may include stains for iron or congo red (amyloidosis) as well as flow cytometry, cytogenetics, FISH. ...Read more
Hypocellular marrow: The normal bone marrow is a mixture of cells and fat. Hypocellular marrow means the marrow has fewer cells in the bone marrow space that is expected for that patient's age. There are many causes for this including nutritional deficiencies, bone marrow failure syndomes, pre-leukemia (myelodysplasia), prior chemotherapy, toxins and medications. ...Read more
Can any doc tell me what's meant when a bone marrow biopsy/aspiration report shows hypocellular marrow?
Bone marrow: Bone marrow cellularity refers to how much of the marrow is making blood cells, and how much is fat. As people age, it tends to decline and move more centrally. Severe hypocellularity may indicate aplastic anemia or even leukemia, which needs treatment. Lesser degrees may or may not, depending on other symptoms and lab findings. ...Read more
Bone marrow biopsy/aspiration (chronic cytopenias/fatigue) f/u appt delayed 4 karyotyping. Is that usually to check CML or what else is possible? Thx
Karyotype important: There are many things that cause low counts. CML isn't one of them - that causes high counts. Getting the genetic testing is very important for making an accurate diagnosis no matter what the diagnosis. I always make my patients wait for that before they come in for their follow-up appointment. I know it's hard to wait, but it's better to get the full and accurate picture all at once. ...Read more
Dad was prescribed pyrodixine to treat his moderate anemia after bone marrow biopsy and aspiration done. Dr. Said no cancer. What s diagnosis options?
Biopsy is tissue removed by needle or cutting to remove part of a body part. It is usually a small amount of material that is processed by a pathologist. Most of the time it is stained and looked at through a microscope to arrive at a diagnosis. Special processes are done for some tissues or problems. The purpose is to tell what the problem is (diagnosis). ...Read more
Bone marrow is the flexible tissue found in the interior of bones. In humans, red blood cells are produced in the heads of long bones, in a process known as hematopoesis. On average, bone marrow constitutes 4% of the total body mass of humans; in an adult weighing 65 kilograms (140 lb), bone marrow accounts for approximately ...Read more
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