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Doctor insights on: What Are The Common Causes Of High Pancreatic Enzyme Levels

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Dr. Michael Gabor
3 doctors shared insights

Pancreas (Definition)

Abdominal organ. It is digestive organ: it secretes enzymes into the small bowel which break down food and help its absorption. It is also an endocrine organ: it produces hormones involved in sugar control and control of digestion. Insulin is one of these hormones. Diabetics either lack Insulin (type 1 diabetes) or have inadequate ...Read more


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What are the common causes of high pancreatic enzyme levels?

What are the common causes of high pancreatic enzyme levels?

Pancreatitis: Inlammation of the pancreas, pancreatitis, is most commonly caused by a gallstone blocking the entrance of the pancreatic duct into the intestine, or alcoholism. Less common causes include side-effects of certain drugs, very high triglyceride levels, and anatomical abnormalities of the pancreas. ...Read more

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Why is my husbands lipase 450 and amylase 250 so high. They said he has cirrossis of the liver. Those are pancreatic enzyme's.

Why is my husbands lipase 450 and amylase 250 so high. They said he has cirrossis of the liver. Those are pancreatic enzyme's.

I'm sorry: Elevated lipase and amylase can result from ongoing damage to the pancreas from alcohol -- perhaps refluxing up a damaged duct, or he may have a cystic fibrosis variant, a hereditary pancreatitis, or any of several other entities. Few diseases truly involve only one organ, and he may have more than one thing going on. This sounds serious and I am glad he has you to care for & love him. ...Read more

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Are there any side effects to taking pancreatic enzyme supplements?

Are there any side effects to taking pancreatic enzyme supplements?

Yes for some...: Virtually all supplements have possible side effects. Most people tolerate pancreatic enzymes well but people with gastritis/ sensitive stomachs often will experience stomach pain/irritation from taking protease enzymes that are included in most enzyme supplements. Some people may get loose stools from enzymes. It is also possible to react to fillers/binders/additives in any med or supplement. ...Read more

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Will taking pancreatic enzyme supplements help absorb other supplements like zinc?

Will taking pancreatic enzyme supplements help absorb other supplements like zinc?

Scam: If your pancreas is normal, i.e., you do not have cystic fibrosis and have not totally ruined it by drinking, there is no reason to take these pancreatic enzymes. They are a health fraud. So is almost all of what you have read about taking zinc; it will just upset your stomach. ...Read more

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Is it safe to take over-the-counter pancreatic enzyme supplements?

Be aware: Do not take any medication unless there is a valid need or reason. Always follow the doctor's or manufacturer's directions. ...Read more

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Is it safe to take pancreatic enzyme supplements and clonazepam?

Listen to your body: Pancreatic enzymes are generally safe and since Clonazepam is an oral medication it is not degraded by normal levels of pancreatic enzymes. If one has not taken either enzymes or clonazepam, it is always wise to start one at a time and observe how one's body responds. If one notices a beneficial response one can trust that the combination is safe. ...Read more

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How does an MD determine the amount of Creon needed--pancreatic enzyme insufficiency besides asking about fat content in foods. Any blood tests, etc.?

How does an MD determine the amount of Creon needed--pancreatic enzyme insufficiency besides asking about fat content in foods. Any blood tests, etc.?

No specific: testing...Your general health/weight and the frequency/consistency of your stools ..in other words good CLINICAL JUDGEMENT will determine the dosage etc Hope this helps Dr Z ...Read more

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Why when a stone obstructs in bile duct can trigger pancreatitis? Is it somehow related to activation of pancreatic enzyme to become active? Tha k

Why when a stone obstructs in bile duct can trigger pancreatitis? Is it somehow related to activation of pancreatic enzyme to become active? Tha k

Anatomy: The bile duct passes through the head of the pancreas and is connected to the pancreatic duct. If a stone obstructs the bile duct where it passes through the pancreas it will cause inflammation of the pancreas as well as liver problems. ...Read more

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Enzyme (Definition)

An enzyme causes the transformation of a compoond to another compound. In living structures, it is the transformation of a protein to another form. An example is from an inactive state ...Read more