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What Are The Causes Of Sickle Cell Anemia
You may be confused.: Fetuses do not suffer from sickle cell anemia in utero because they have a different type of hemoglobin (fetal) that is unaffected even in individuals destined to have sickle cell disease later in life. Affected fetuses come from affected or carrier parents and sickle cell disease is a genetic condition without cure at present. See a genetic counselor to discuss these issues in detail. ...Read more
This is a genetic disorder in which hemoglobin is abnormally made., more common in people of african descent. This abnormality causes red blood cells to become stiff and fall apart. This can cause very specific symptoms: pain, pneumonias, strokes, spleen problems, and many other problems. Some have mild disease, some ...Read more
Symptoms of SS: The altered shape of the red blood cells causes them to stack up together and clog blood vessels, depriving the tissues of adequate blood supply and oxygen. The tissues then die (infarct) and this causes pain. The red cells also rupture or are eaten by the spleen and cause anemia. The spleen itself will gradually infarct, leaving the patient susceptible to infections. ...Read more
Malaria doesnt cause: Sickle cell anemia is a hereditary disease caused by a mutation in the dna coding for hemoglobin. Scientists have long known that sickle cell anemia protects carriers from malaria infections, which could be advantageous in certain parts of the world. Malaria does not cause sickle cell anemia. ...Read moreSee 1 more doctor answer
Increased sickling: Multiple factors can result in increased sickling during anesthesia and surgery. Chemical changes in the acidity of the blood, oxygen carrying capacity of the blood, body temperature, etc all increase the risk of sickling. Therefore transfusions are strongly recommended prior to surgery to reduce the total number of red cells with hemoglobin s prior to surgery in an attempt to minimize the risk. ...Read moreSee 2 more doctor answers
Compromising organs: Sickling of the red blood cells can occur from stress or ketoacidosis (diabetes out of control) and causes of low oxygen in the lungs or blood. This will cause the sickled cells to obstruct the flow of the cells that still are able to carry oxygen to the various organs such as the liver, the brain, heart, muscles and any and all tissue. This compromises function of the organ or tissue. ...Read more
The bad cells: In simplest terms, the sickle ("bad") cells need to be removed because they get "trapped" in the liver where they are disposed of. These cells don't live as long as normal red blood cells, so the liver is working over time. ...Read more
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