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What Are The Causes Of Anemia
Low RBCs: Anemia is a low red blood cell (rbc) count, also measured by hemoglobin, which is the oxygen-carrying protein within the rbc. Anemia is secondary to decreased RBC production (bone marrow disease, nutrition, kidney dz, etc) or increased destruction ("hemolytic")/blood loss (surgery, trauma, GI bleeding, etc). ...Read moreSee 1 more doctor answer
Macrocytic anemia: The most common causes of macrocytic anemia are B12 (ruled out for you) and folate (folic acid) deficiencies. Folate (folic acid) deficiency can be caused by diet (very rare - folate (folic acid) is everywhere), celiac disease, alcoholism, or hemolysis (autoimmune process, for example). Rarer causes include aplastic anemia and myelodysplastic syndrome (mds). If not clear to your doc, may need to see hematologist. ...Read moreSee 1 more doctor answer
Various causes: most common are hemoglobinopathies. Abnormal hemoglobin genes cause decreased production or unstable hub, such as sickle cell, thalassemia and Hgb. E. Abnormal cell membrane proteins making red cells fragile such as hereditary spherocytosis or elliptocytosis. Less common are genetic conditions that produce damaged bone marrow cells like Fanconi's anemia. ...Read more
Autoimmune disease: Pernicious anemia is an autoimmune disease producing autoantibodies against intrinsic factor found in the lining of the stomach. This leads to lack of absorption of vitamin B12 which is important in making blood cells and for nourishment of the nervous system. Treatment would be by replacement of B12 via injections or absorption into the body by other means (nasal spray). ...Read more
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