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Doctor insights on: What Are The Causes And Symptoms Of Down Syndrome

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What are the symptoms of down syndrome?

What are the symptoms of down syndrome?

See below: Flat face, hypotonia, and intellectual disability. One third of patients develop congenital heart defect (s). ...Read more

Dr. Kathryn Akin
654 Doctors shared insights

Down Syndrome (Definition)

A genetic chromosome 21 disorder causing ...Read more


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Are there limited symptoms of down syndrome?

Are there limited symptoms of down syndrome?

Yes: There are high functioning down's and then there are children more severely affected. ...Read more

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What are the signs and symptoms of down syndrome?

What are the signs and symptoms of down syndrome?

Down's syndrome: Delayed maturation of brain & body, result in small chin, oblique eye fissures with skin folds on inner corners of the eyes, flat nasal bridge, poor muscle tone, protruding tongue, flat face, short neck, lax joints, larger space between big toe & second toe, short fingers, short stature & bowed legs, obesity as they grow older. ...Read more

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What are the most common signs and symptoms of down syndrome?

Facial character: It is typically associated with a delay in cognitive ability (mental retardation, or mr) and physical growth, and a particular set of facial characteristics.

The average iq of young adults with Down syndrome is around 50, whereas young adults without the condition typically have an iq of 100. ...Read more

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What are the signs and symptoms of Down syndrome and what can be done to fix it?

See NIH website: See: www. Nchi. Nlm. Nih. Gov/pubmedhealth/pmh0001992/ for a full review.
Down syndrome results when a kid is born with too much chromosome material in his/her cells which confuses the system & results in anomalies & poor development. It cannot be fixed, but outcome can be improved with attention to associated problems. ...Read more

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What are the fetal sign and symptoms of down syndrome?

What are the fetal sign and symptoms of down syndrome?

Maternal serum: Screening at 10-14 weeks + fetal ultrasound (fus) at 11-14 weeks + maternal "quad" screen at 16 weeks detects ~ 95% of fetuses with Down syndrome with <5% false-positive rate. Increased size of the fluid-filled space at the nape of the neck & abnormalities of blood flow in the heart are signs on early fus. Diagnostic testing is chorionic villus sampling at 10-12 weeks or amnio at 15-18 weeks. ...Read more

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What causes down syndrome?

DNA defects: Chromosome 21 seems to be the cause. Two most common types are trisomy 21 where ther is an entire extra chromosome in each cell. The other is translocation where only an extra piece of the chromosome is found. It can be an isolated defect or an inherited defect. Rare exotic forms include polyploidy and haploid forms and chimeras. Sorry you asked? ...Read more

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What are the different causes down syndrome?

What are the different causes down syndrome?

Downs syndrome: Trisomy 21 when there is an extra chromosome at 21, mosaicism when some cells have trisomy and others not, robertson translocation [n which long arm of 21 chromosome is attached to another chromosome often chromosome 14. ...Read more

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Description and symptoms of kids with down syndrome?

Description and symptoms of kids with down syndrome?

Many criteria: 1. Epicanthic folds give the superficial impression of mongoloid appearance. 2. A staight across palmar crease like that of an ape so it is called a symian crease.3. Obvious developmental delay.4.Often a tongue that seems to be too big for mouth. ...Read more

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What are symptoms of major diseases in down syndrome?

What are symptoms of major diseases in down syndrome?

Variable: The most significant symptoms happen if the child with down's has cardiac defects. Some of these defects may require surgery. Immunity issues may exist that predipose to infection and/or leukemia (a blood cancer). ...Read more

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Why are women the cause of Down syndrome more often than men are?

Why are women the cause of Down syndrome more often than men are?

Non dysjunction: This term means that one of the earliest divisions of the embryo after conception delivers 3 number 5 chromosomes to a daughter cell and only one to the other daughter cell. The trisomy cell survives to create down's syndrome babies. ...Read more

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I'm wondering why are women the cause of Down syndrome more often than men?

Selection variables: If a woman generates an egg that contains 2 rather than 1 chromosome 21's, the addition of a 21 from the sperm will cause the trisomy 21 condition. Some of these miscarry & some deliver. When males generate a sperm that carries irregular information, there is speculation that the ones with bad information do not swim as well & thus can't pass the defect. ...Read more

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What are the causes of people with Down syndrome to live fifty years or less?

Poor health: The expected lifespan of a ds patient born today exceeds 60 years if they have access to the basic medical care & dietary resources of average individuals. They do have higher risks for a variety of health issues involving their glands (thyroid, diabetes) their bones (scoliosis, joint pain & weakness) and the impact of obesity is much worse for their overall health. ...Read more

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Are there genetic causes of down syndrome?

Are there genetic causes of down syndrome?

Yes: Down syndrome is a genetic condition caused by an extra copy of chromosome 21. However, it is usually not inherited in families. ...Read more

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Does teething cause down syndrome?

Not at all: Down syndrome is a genetic disorder, you can only be born with it, teething has nothing to do with it, your baby is safe. ...Read more

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Which type of mutation causes down syndrome?

Which type of mutation causes down syndrome?

Trisomy 21: Down syndrome is also called trisomy 21. That means that there is a partial or complete third copy of the chromosome 21. It is the most common chromosomal abnormality. ...Read more

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What are the causes of people to be born with down syndrome?

What are the causes of people to be born with down syndrome?

Extra chromosome 21: A woman's chances of giving birth to a child with Down syndrome increase with age because older eggs have a greater risk of improper chromosome division. By age 35, a woman's risk of conceiving a child with Down syndrome is 1 in 400. By age 45, the risk is 1 in 35. However, most children with Down syndrome are actually born to women under age 35 because younger women have far more babies. ...Read more

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Is Down syndrome always caused by a defect in the 21 chromosome?

Extra chromosome 21.: Either complete or partial trisomy for chromosome 21 is always responsible for down syndrome. ...Read more

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What are some of the causes for a child to be born with down syndrome?

What are some of the causes for a child to be born with down syndrome?

Several possible: The features of Down syndrome are dependent on the addition of one extra segment of a 21 chromosome which is more likely as women age. You can get this several ways. The traditional DS (~95%) has 3 copies of a 21 chromosome. About 4% have the specific extra 21 piece stuck on a regular chromosome (trans-location).About 1% have a mosaic of some normal and some 21 trisomy in variable amounts. ...Read more

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Need expert help here. What are some symptoms that Down syndrome patients have?

Need expert help here. What are some symptoms that Down syndrome patients have?

Many: Down syndrome patients may have prominent tongue, joint laxity and hypotonia, congenital heart defects, hyper or hypothyroidism, gastrointestinal issues including aspiration and ge reflux, neurologic mental retardation, constipation and hirschsprung's disease, congenital bowel issues (bowel atresias). Some with mild symptoms and findings and others more severe. ...Read more

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What are the causes of people with Down syndrome to have similar facial features?

Chromosome influence: The size and shape of the skull and facial features of Down syndrome patients is heavily influenced by the effect of the extra chromosome present in every cell of the body. The same goes for eyes, hands, feet, all of which require a lot of decoding during formation to produce the structures. Other chromosome defects produce some common features to those born with a specified extra chromosome. ...Read more

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Hi, a quick question, I have a six week old niece, when she was born there was worries she was down syndrome, she got all the tests and thank god they came back clear, my question is could the tests have been wrong, cause there is times you look at her a

Hi, a quick question, I have a six week old niece, when she was born there was worries she was down syndrome, she got all the tests and thank god they came back clear, my question is could the tests have been wrong, cause there is times you look at her a

Test limits: I will assume that the tests that were completed was specific to look for a chromosomal abnormality. The typical ds diagnosis can be ruled out, but the test does not exclude other problems that can give an infant an unusual look, or might be a problem in the future. The pcp can monitor the situation over time & look for other issues if there appears to be a need for additional study. ...Read more

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What are the symptoms and treatments of down syndrome?

Long story!: The problem is duplication of genetic material (chromosome 21) in every cell of the body. There are facial features, heart problems, reduced muscle tone, and spinal, gi, ent, thyroid and blood-related issues as well. The biggest issue is mental deficiency. Ongoing surveillance and intervention by your pediatrician are important. So is developmental and school-based help. ...Read more

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What are the causes of down syndrome, genetically speaking?

What are the causes of down syndrome, genetically speaking?

Extra chromosome mtl: The traditional ds patient has an extra 21 chromosome (c) that resulted from an improper splitting of the c pairs as the egg is being formed. At conception dad's 21 is added to the pair already there, while all the other chromosomes just have a pair. Cell division from conception will place the triplet 21 in every cell of the body, and the imbalance of the material leads to the features of ds. ...Read more

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Av canal defect, can this cause down syndrome?

Av canal defect, can this cause down syndrome?

Other way around: Atrioventricular (av) canal defect is a relatively common congenital heart defect in children born with down syndrome. Down syndrome "causes" av canal defects, not the other way around. Av canal defect is a major congenital anomaly with the potential to cause severe symptoms. However, in most cases, av canal defect can be repaired. High levels of surgical skill is important for best outcomes. ...Read more

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Which type of chromosomal mutation causes down syndrome?

Which type of chromosomal mutation causes down syndrome?

Not mutation, number: Down syndrome is an abnormality of chromosome numbers, not a trait or mutation in the gene code. During conception only one of chromosome of each pair is given by both parents to the fertile egg. If a parent adds their 2 nbr 21chm to the other parents nbr 21, 3 end up in the egg ; the excess 21 causes the all the problems. Rare forms are causes by a extra piece of a 21, but that's another issue. ...Read more

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What causes high risk of my little one having down syndrome?

What causes high risk of my little one having down syndrome?

Advanced mom age: The risk of having a baby with any form of chromosome defect increases as the mother ages. It is lowest in her early 20's and rises above 1% at 40 and approach 5% at 50. It is a fact of life, that environmental toxic factors may eventually cause changes to the eggs that yield this risk. ...Read more

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Are short toes a symptom of down syndrome?

Are short toes a symptom of down syndrome?

Yes: Short toes and spacing between the great toe and second toe are commonly seen in patients with down syndrome. ...Read more

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Can you show me more than 5 syndromes that are cause by DNA mutation such as down syndrome, etc?

Can you show me more than 5 syndromes that are cause by DNA mutation such as down syndrome, etc?

See link: Here is a good starting point for you:

http://www. Ncbi. Nlm. Nih. Gov/books/nbk1116/. ...Read more

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What are the symptoms of heart disease in down syndrome?

What are the symptoms of heart disease in down syndrome?

Multiple symptoms: Down syndrome can have multiple congenital heart disease which includes atrial septal defect, hypoplastic left ventricle, tetrology of fallot, transposition of great vessels and ventricular septal defect. Some defects can have very few or no sign and symtoms while other may have bluish tinted nails or lips or fast or trouble or others may tire easily when feedind, or to be very sleepy. ...Read more

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Can you tell me about causes of high risk of Down syndrome during pregnancy?

Can you tell me about causes of high risk of Down syndrome during pregnancy?

Chromosome defect: Ds is one of the more common chromosome (c) defects that can survive pregnancy (many others miscarry). It usually happens when an egg with an extra 21c combines with a normal sperm ; creates a baby with the extra 21c in all tissues. Risks vary with age and are lowest in the early 20's (1/2000), rising to 1/100 at about 40 ; 1/12 at 49.Various prenatal tests can pick up signs early on. ...Read more

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I was wondering what are the biochemical processes that cause Down syndrome people to be more prone to congenital heart diseases?

I was wondering what are the biochemical processes that cause Down syndrome people to be more prone to congenital heart diseases?

Unknown: The heart is a very complex organ. We still do not fully understand how the normal heart develops in the fetus. We understand even less about what causes the heart to develop abnormally. Although 40-50% of patients with Down syndrome have congenital heart dis., and we know what causes down syndrome, we do not yet understand why this leads to heart defects (likely due to abnormal gene expression). ...Read more

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Why do Down syndrome patient have their eyes slanted upward, is it caused by the chromosome 21, I need an explanation on why their face look different?

In the genes: All of our features are determined by our genes. The appearance of your eyes, nose, mouth, hair color, skin color, among other features are all inherited. When there is a defect in the gene coding, changes can occur. Facial features can change with in utero exposure such as alcohol (fas syndrome). For downs, the extra 21 causes low ears, slanted eyes, simian crease as well as organ problems. ...Read more

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I'm 11 weeks pregnant and I was wondering if not taking folic acid every day will cause the baby to have Down syndrome or any other health issues?

Probably not: While Folic Acid is recommended during pregnancy, the lack of supplement does not cause defects. Supplements decrease the risk that your child will have a neural tube defect such as spina bifida. It has no bearing on the risk for down's. ...Read more

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If your are infected with chlamydia, can that cause birth defects in the child? Even if I get treatment to cure it. Could it cause down syndrome?

If your are infected with chlamydia, can that cause birth defects in the child? Even if I get treatment to cure it. Could it cause down syndrome?

Only if untreated.: Chlamydia infection is of no risk to the fetus if treated properly (that includes your sexual partner). It has nothing to do with down syndrome. If left untreated or undiagnosed or recurrent at the time of delivery then ophthalmia neonatorum with trachoma can develop with severe consequences for the infant's eyesight. That's why Erythromycin ointment is applied to all newborns' eyes prophylactical. ...Read more

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I am doing a presentation for my class on down syndrome and I need to know why it isn't dominant or recessive. P.S. I need a simplified answer

Seek info here: Lots of HT doctors have answered this for others - here's a start. Just dig a bit further, but it's a good reply.


Source: HealthTap, https://edc1.healthtap. Com/user_questions/22610 ...Read more

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What is down syndrome?

What is down syndrome?

Chromosome defect: Ds is one of the more common chromosome (c) defects that can survive pregnancy (many others miscarry).Eggs are supposed to have a single 21c & combine with the 21 from dads normal sperm.Here a pair of moms 21c +dad's 21 creates a baby with the extra 21c in all tissues. This extra material confuses the creation of body parts causing ds. Various prenatal tests can pick up signs early on. ...Read more

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Is Down syndrome inherited?

Is Down syndrome inherited?

Not usually: The only way to inherit Down syndrome is if one parent has Down syndrome and passes 2 copies of chromosome 21. Few people with ds reproduce, so that is not usually a factor. ...Read more