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Doctor insights on: What Are The Benefits Of Tysabri V Other Ms Drugs

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What are the benefits of tysabri (natalizumab) v. Other MS drugs?

What are the benefits of tysabri (natalizumab) v. Other MS drugs?

Hard to answer: Tysabri (natalizumab) is a potentially effective treatment for MS but your question would be difficult to answer. Tysabri (natalizumab) is approved for the treatment of aggresive or refractory MS where other equally effective medications have not worked. This is because of a possibly fatal side effect called pml which may cause more damage than the disease. Use requires an experienced doctor and close monitoring. ...Read more

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Can I take tamiflu if im on MS drug tysabri (natalizumab)?

Can I take tamiflu if im on MS drug tysabri (natalizumab)?

Yes, but see below: We have good evidence that flu vaccines with dead viruses are effective with tysabri (natalizumab).. Tamiflu is an antiviral med that may alleviate some of flu symptoms and shorten duration, and would be unlikely to cause problems with tysabri (natalizumab). Might be wiser, though, to get a flu shot, and avoid nasal vaccine, as it is a live attenuated virus and adds risk. ...Read more

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I'm only 24, and tysabri (natalizumab) has been my miracle drug for ms. But, i've just tested positive for the jc virus. Do i continue? What is next best options?

I'm only 24, and tysabri (natalizumab) has been my miracle drug for ms. But, i've just tested positive for the jc virus. Do i continue? What is next best options?

A matter for your MD: Good question. Is it safe to continue Tysabri (natalizumab) if blood testing for JC is positive? Yes, sometimes. Are there alternative treatments to Tysabri (natalizumab)? Yes, there are good alternatives. The alternatives for you depend a bit on your personal history, such as what worked, and what did not, and perhaps why. Another question is whether confirmatory testing for JC is needed. Hope that helps! ...Read more

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Dx w ms, yr ago. Tx: on 7 inf. Of tysabri (natalizumab). Feel cold coming on, hvn't been sick w cold/flu since. Worry abt getting sick w dx. Sugg meds, coping, etc-?

Dx w ms, yr ago. Tx: on 7 inf. Of tysabri (natalizumab). Feel cold coming on, hvn't been sick w cold/flu since. Worry abt getting sick w dx. Sugg meds, coping, etc-?

Advice: The Tysabri (natalizumab) will not make you infection necessarily worse, and you should be treated by your doctor in the standard approaches for colds or flus. Since viral infections might cause fever, worsening your symptoms, high temps should be controlled. Notify your neurologist, as a virus can promote a true relapse, also, and get meds, if your symptoms worsen longer than 24 hrs. ...Read more

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Is tysabri (natalizumab) a treatment for ms?

Is tysabri (natalizumab) a treatment for ms?

Yes: This is a monoclonal antibody, infused once monthly, and is the currently most potent medication on the market for MS. In several cases, a deadly infection called PML has occurred with pts taking this medication, but blood tests can predict risk, and if positive can prompt the discontinuation of Tysabri (natalizumab).. Drug can be used early or late, but is approved for first line. ...Read more

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What percentage of MS patients are on tysabri (natalizumab)? Is there a big chance of bad side effects?

Answer continues...: If, you have tested negative for jc virus antibodies, your chance of getting pml is around 0.09/1, 000. On the other hand, if you have tested positive for jc virus antibodies, have been on tysabri (natalizumab) therapy for over two years and have prior exposure to immunosuppressant therapies, such as azathioprine, methotrexate, micophenolate, Cyclophosphamide or mitoxantrone, your risk becomes 11.1/1000. ...Read more

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Is it normal for someone just told they had MS to be put on tysabri (natalizumab) before other treatment?

My opinion: Tysabri (natalizumab) has an FDA indication for first line use, and if a patient has quite active MS, I believe it is foolhardy to use less effective medications to start and then scale up after damage has become permanent. The first 5 yrs seem most critical in the quest to stabilize MS. ...Read more

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I fired nuero. Can anyone tell me how bad of rebound to expect with MS coming off of tysabri (natalizumab) infusion w/o meds. Health want allow them. See profile?

New provider: With ms you should be under the care of a doctor. Okay to change doctors. While you are looking for your next ms provider/neurologist okay to ask your regular doc for referral, call your local ms foundation and ask for referrals. You have options. Be well. ...Read more

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I have MS and am currently on tysabri (natalizumab) (monthly infusion).Am i able to take clenbuterol?I have been on this before i had ms.Tysabri (natalizumab) and clenbuterol ok?

Not a problem: Clenbuterol is a powerful bronchodilator, and will unlikely have any adverse interaction with a drug which affects lymphocyte trafficking across the brain blood barrier. In ms, we consider part of the focus to involve th-1 cells, but in asthma, this is more of a th-2 process. Complex, but do not worry, you can use your medication. ...Read more

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I'm on tysabri(for MS and have had a cold for the past 3 weeks.Penicillin, anti inflamitories, cold and flu tablets are not working.Should i be worried?

I'm on tysabri(for MS and have had a cold for the past 3 weeks.Penicillin, anti inflamitories, cold and flu tablets are not working.Should i be worried?

Infection risk inc.: Patients taking tysabri (natalizumab) are at an increased risk for infections. The most common were pneumonias, urinary tract infections , gastroenteritis, vaginal infections, tooth infections, tonsillitis, and herpes infections. Patients also usually have monthly blood work which will assess your white count. Please let your neurologist know so you can have a more thorough evaluation. Well wishes. ...Read more

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