Doctor insights on:
What Are Some Of The Major Causes Of Infertility In Couples
Age,anatomy,hormones: Reasons for female infertility include age. Fertility declines significantly after age 40. Chromosomal or genetic conditions like turner's syndrome are cause. She may have abnormal anatomy such as a malformed uterus which cannot support pregnancy. Lack of ovulation due to ovarian cysts or hormones are problems. Chemotherapy can cause early menopause. Some women don't know when to have sex. ...Read more
Fertility in 19th C: I don't believe there's much real data to answer , but case reports in lancet as far back as civil war support that causes were probably similar to now: ovulatory, tubal, endometriosis. There's a fascinating case report of a surgeon cannulating proximal fallopian tube with a whalebone in 1898! delayed child-bearing of course was less common. Medical historians please correct me if needed! ...Read more
Major causes: Hypertension for many years, atrial fibrillation, and arteriosclerotic blockage in the carotid (neck) arteries are the 3 commonest causes. Rarer causes are: ruptured berry aneurysms, CNS infections, vasculitis, endocarditis, hypercoagulable states and strokes of unknown cause (cryptogenic). ...Read more
Chromosomes/ age #1: The most likely cause of first trimester miscarriages is chromosomal abnormality in the fetus. This is true for all ages but is a higher percentage as the woman's age increases over 35. This is usually a random chance event when the egg and sperm meet. Other causes are hormonal imbalance, infections, uterine abnormalities - fibroids, septum, scarring, and less often immune or clotting factors. ...Read more
Multiple: Risk for developing depression & anxiety may involve the combination of multiple genes with environmental and other factors. Family history of depression & anxiety is commonly found with women w/these disorders, but isn't a hard or fast rule. Losing a parent before age 10, hormonal changes throughout life, current losses, medical illnesses, & life & relationship stresses all can contribute. ...Read more
Cause of infertility: The causes are many. 40% of cases it's due to a problem in the woman, and 40% are due to a problem in the male. The remaining 20% are of unknown origin. You need to go through a work up (which can be completed in 2 moths) prior to starting treatment. The majority of couples can be helped and will overcome their infertility. ...Read more
Symptoms of Diabetes: Symptoms of diabetes are the same no matter what the age. They include increased thirst, urinating large volumes, blurry vision, yeast infections, and in some cases a dark area on the back of the neck, arm pits, any body folds especially, called acanthosis nigricans. If there is any question of diabetes, the teenager should see a doctor for blood tests. Diabetes is a lifestyle disease. ...Read more
Several: Male factors include testicular injury, infection, congenital anomalies, mumps, torsion. Women can present with chromosomal anomalies, tubal factor from infection or prior surgery, polycystic ovary, endometriosis, ovarian dysfunction, unexplained infertility & lack of sexual frequency. ...Read more
PTSD symptoms: Persistent re-experiencing of a traumatic event that threatened death or serious injury, or that one witnessed in another. Persistent avoidance of stimuli which might remind one of the event, and generalized numbing. Symptoms of increased arousal such as intense anxiety, difficulty falling asleep, nightmares if you do sleep, exaggerated "startle" responses, and hypervigolance are also common. ...Read moreSee 1 more doctor answer
FDA approval: The biggest obstacle before the widespread use of gene therapy in the usa is obtaining fda approval. A phase iii trial is required prior to approval, treatment must show efficacy and minimal side effects compared to the disease being treated. Phase 3 trials have had problems with immune system rejection of the wrapping material/virus for the gene therapy as well as issues with dosing.. ...Read more
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