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Doctor insights on: What Are Some Of The Longterm Side Effects Of Rituxan

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What are some of the longterm side effects of rituxan (rituximab)?

What are some of the longterm side effects of rituxan (rituximab)?

Not common: The long-term side effects are uncommon though can be serious. These include: low immunoglobulin levels, pml (brain infection caused by jc virus), reactivation of hepatitis b infection with resulting liver damage in previously infected patients, and uncommon other serious bacterial, viral and fungal infections. ...Read more

Dr. William Singer
71 doctors shared insights

Rituxan (Definition)

Rituxan is an antibody based agent which is a kind of ...Read more


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Has anyone had side effects from rituxan (rituximab)?

Has anyone had side effects from rituxan (rituximab)?

YEs: The first exposure to Rituximab frequently leads to allergic symptoms known as an anaphylactoid reaction. This may lead to red, itchy skin, wheezing, shortness of breath, tightness in the chest, high or low blood pressure. This reaction usually does not happen with subsequent exposure. ...Read more

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I have heard chemo has very bad side effects.My dad just had his first chemo with rituximab+chop.Its been 2 days and hes not that bad.Is that normal?

I have heard chemo has very bad side effects.My dad just had his first chemo with rituximab+chop.Its been 2 days and hes not that bad.Is that normal?

Yes: R-chop is a generally well tolerated chemotherapy regimen. Rituximab can lead to allergic-type reactions with the first dose. Hair loss will begin about 3 weeks after the first r-chop dose. Fatigue and low blood counts may occur as your dad goes through treatment. ...Read more

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Any side effects from rituxan (rituximab) therapy?

Any side effects from rituxan (rituximab) therapy?

Mostly infusion rxns: Rituxan is given intravenously slowly at first to look for common immediate reactions like chills, fever, shakes, itching, hives, headache all of which could be prevented or lessened by giving premedications like Benadryl (diphenhydramine) and steroids. Reactivation of hepatitis b, lowering resistance to infections, rapid destruction of tumor cells causing i'll effects to organs (tumor lysis) can also occur. ...Read more

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How long after rituxan (rituximab) treatment will the side effects go away?

How long after rituxan (rituximab) treatment will the side effects go away?

Most likely.: What side effects do you speak of? Most side effects of Rituximab occur during the infusion itself; I have very few folks complain of anything afterwards except maybe fatigue (that is if they receive Rituximab by itself). It does suppress the b lymphocytes for months but usually that translates into nothing. Patients who have had heart pain or irregular heartbeats in the past may experience .Reed. ...Read more

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How long after treatment with rituxan (rituximab) will side effects go away?

What SE?: What side effects (from rituximab)? About 25% of people will have an "infusion reaction" on initial dose with possible hives, shortness of breath, shaking, etc. That is usually not a condition that persists after the infusion is completed. Other side effects can come from killing cancer cells quickly such as tumor lysis syndrome, or some more rare long term Rituximab side effects? ...Read more

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Can people take rituximab drug as a treatment of mmn disease alongside IVIg drug as the doctor described and what are the side effects ?

Uncertain what mmn?: I would like to help but need more information. Depending on the setting you can use rituxan (rituximab) to help certain conditions and sometimes other meds are used. These are things to discuss with your physician. ...Read more

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I m suffering from r. Arthritis after using all the drugs my doctor is now recommending mabthera (rituximab). Wat r its side effects? Is it safe 4 me?

I m suffering from r. Arthritis after using all the drugs my doctor is now recommending mabthera (rituximab). Wat r its side effects? Is it safe 4 me?

Can be safe: Can be safe if tests for tuberculosis and chest x-ray are normal and there are no major infections present. Side effects are increased susceptibility to infection and slight increase in risk of cancer. The other side effects are less common, but are similar to those found with tumor necrosis factor inhibitors/blockers. ...Read more

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Neupogen can increase WBC after late onset neutropenia (LON). Any prescription that gives long term prevention of the LON side effect after Rituximab?

 Neupogen can increase WBC after late onset neutropenia (LON). Any prescription that gives long term  prevention of the LON side effect after Rituximab?

Neutropenia: is not usually treated except for absolute neutropenia. Hence usual practice is to use Neupogen or G CSF or prevent or treat absolute neutropenia so that benefits outweigh the adverse effects ...Read more

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What effects can rituxan (rituximab) have if a women is pregnant ?

What effects can rituxan (rituximab) have if a women is pregnant ?

Unknown: Rituxan (rituximab) has been assigned to pregnancy category c by the fda. Animal studies have not been conducted. There are no controlled data in human pregnancy. There are no data on whether Rituxan (rituximab) can cause fetal harm when administered to a pregnant woman. . Postmarketing data indicate that b-cell lymphocytopenia generally lasting less than six months can occur in infants exposed to Rituxan (rituximab) in utero. ...Read more

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How long after treatment with rituxan (rituximab) will the effects go away?

How long after treatment with rituxan (rituximab) will the effects go away?

Median half life 32d: The median half life of Rituxan (rituximab) is 32 days. It takes approximately 5 half-lives before a drug is considered "gone" from the system. Therefore a median time-period would be 160 days from completion of treatment. Remember measurement of drug in the system is not the same as the side-effect of the drug or the length of time the lymphocyte population is affected. ...Read more

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What to expect from rituximab effects?

Rituxan (rituximab): Please open the link http://www.Nlm.Nih.Gov/medlineplus/druginfo/meds/a607038.Html.

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Can you tell me how is the rituximab 500mg?

Not enough info: What is this med being used to treat? It is generally well tolerated. Infection is the major risk. ...Read more

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Does rituximab lower your immune system?

Does rituximab lower your immune system?

Yes: Rituximab (rituxin) is a monoclonal antibody to cd20 an antigen located on lymphocytes. One consequence of using this drug is a drop in lymphocyte numbers (bad cells and good cells). This decline lowers the effectiveness of the immune system for a period of time. ...Read more

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Does having rituximab lower your immune system?

Does having rituximab lower your immune system?

Yes: Rituximab is directed against an antigen found on lymphocytes (cd20). It attaches to this antigen and causes destruction of the lymphocyte. Its action is indiscriminate therefore the lymphocyte population is transiently decreased leading to a lowering of the function of the immune system for brief periods of time. ...Read more

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Can your body become immune to rituxan (rituximab)?

Can your body become immune to rituxan (rituximab)?

Yes.: If you mean can it stop working for you, yes. Immune reactions to Rituxan (rituximab) also can occur that can make the drug impossible to give safely. ...Read more

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Is rituxan (rituximab) considered a chemotherapy drug?

Is rituxan (rituximab) considered a chemotherapy drug?

Not really: Rituxan (rituximab) is used to treat certain cancers as well as other non-cancer conditions. In the oncology world, we don't think of it as "chemotherapy" because it is a monoclonal antibody that is selective. We use the term chemotherapy for drugs that non-specifically kill fast-growing cells. We call Rituxan (rituximab) a biologic therapy, not chemotherapy. Hope that helps! ...Read more

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Dr. Robert Lowe
68 doctors shared insights

Rituximab (Definition)

Rituximab ...Read more