Doctor insights on:
What Are Side Effects Of Statins
Several drugs exist which lower cholesterol by inhibiting an enzyme in liver cells (hmg-coa reductase) that is involved in cholesterol synthesis. These all have generic names that end in -statin, e.g. Atorvastatin (lipitor) and Simvastatin (zocor). Since nearly all of the meds in this class have been shown to have similar cardiovascular benefits, we often discuss them ...Read more
Potentials: Statins do cause muscular adverse events, and one can experience pain, aching, weakness, and rarely, rhabdomyolysis. Most common is effect on muscle, but rarely, also, effect on peripheral nerve. Your prior polio might make the adverse events far more intense, if they occur, but there is no increased risk of muscle or nerve adverse events in those with prior polio. ...Read moreSee 1 more doctor answer
Usually none: But muscle effects should be closely monitored. ...Read more
Bit diverse: Statins have been getting a bad RAP re: adverse effects. Many symptoms are attributed to statins, but often are not truly related. Muscle aches of a certain type, abnormal liver function tests, vague abdominal discomfort, minor elevation of blood sugar levels, may be noted. Key things to note are that these symptoms & signs are actually uncommon & tend to be dose dependent. Reducing dose helps. ...Read more
Yes: The most common side effects from statins include 1) myalgia and increased CPK from skeletal muscle and 2) elevated liver function tests reflecting liver inflammation. A vast majority of these side effects are benign. There have been instances of severe skeletal muscle damage or severe liver damage but these episodes are very unusual. ...Read moreSee 1 more doctor answer
Liver and myalgias: Statins are beneficial in both primary and secondary prevention of CAD in high risk patients including diabetics. The biggest concern with using them involve a 5-10% incidence of myalgia. Liver enzyme elevation ( >3x normal) occurs 1% of the time. These side effects reverse with cessation of the statin.Dangerous side effects like rhabdomyolisis are rare (1 in several thousand patients). ...Read more
Yes: You may simply stop. There is no need to wean statin medications. ...Read more
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