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Doctor insights on: What Are Side Effects From The Anticonvulsant Depakote

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What are side effects from the anticonvulsant depakote?

What are side effects from the anticonvulsant depakote?

Side effects: Both can cause nausea & headaches. Depakote side effects are tremors, inc. Weight, leg cramps, ataxia, swelling of face, hair loss, irregular menses in females, rash. Zoloft (sertraline) side effects are restlessness & diarrhea. ...Read more

Dr. Jeffrey Cohen
245 doctors shared insights

Divalproex (Definition)

Divalproex, is a seizure medicine, the generic name is valporic acid, it has been in the market as an antiseizure medicine for long time, it is a good medicine, helps to control almost all types of common seizures, partial, generalized, absence, myoclonic, atonic, ..Etc.It can be used as a mood stabilizer in psychiatric patients. It has adverse effects on the liver, ...Read more


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Are there any long lasting side effects to an overdose of Divalproex(depakote) or Venlafaxine(effexor)? Provided that death does not occur.

Are there any long lasting side effects to an overdose of Divalproex(depakote) or Venlafaxine(effexor)?  Provided that death does not occur.

Should resolve: But what prompts your question? Did YOU overdose? If so, once all is destabilized, you should have no lasting damage. But discuss this with your doctor. ...Read more

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What is the definition or description of: side effects of depakote?

What is the definition or description of: side effects of depakote?

Mostly mild: Dyspepsia and/or weight gain are common. A rare side effect is a liver and blood allergy/dysfunction. Less common are fatigue, peripheral edema, acne, dizziness, drowsiness, hair loss, headaches, nausea, sedation, and tremors. An increase of ammonia levels in the blood, which can lead to vomiting and sluggishness. ...Read more

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Hi docs, can you tell me if side effects are noticable on 250mg of divalproex/depakote?

Depends...: It really depends on how your body metabolizes the medication. Most people do not report any side effects on such a low dose of medication. ...Read more

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Side effects of Depakote and zoloft (sertraline)?

Side effects of Depakote and zoloft (sertraline)?

Side effects.: All psychiatric rx's have side effects. If you check with side effects in the pdr, you will not want to take another drug. Mostly, your individual should be concerned about the drug/drug interactions. It is almost unamerican not to be polymedicvated. The prescribing md should talk with the patient about what the drugs will do and more importantly what the drugs will not do. ...Read more

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Help! i know they say don't come off of Depakote urself but I have heard a lot say there were no side effects for them doing so. I also take seroquel (quetiapine)?

Help! i know they say don't come off of Depakote urself but I have heard a lot say there were no side effects for them doing so. I also take seroquel (quetiapine)?

Relapse vs withdrawl: While there are usually no side-effects, ie withdrawal, from stopping depakote, there is a very real risk of relapse. That is, the original problem that led to taking Depakote in the first place could return. Since Depakote is used for serious conditions, stopping this treatment without close monitoring by your doctor could be very risky. ...Read more

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Side effects of depakote, do they go away?

Side effects of depakote, do they go away?

Sometimes: Some side effects go away, or at least get better, over time, and some do not. It sounds like you really need to discuss the situation in more detail with the person prescribing the depakote. ...Read more

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I am worried about long term side effects of my bi-polar meds, depakote, Effexor (venlafaxine) zr as well been on them 12 years. What r the long term side affects?

It Depends: Many folks take Depakote and Effexor (venlafaxine) for years and years without any problems what so ever/ Depakote can have an affect on the liver, so it's good to have some blood tests every year or so. Also, Depakote can cause weight gain, and if a person gains too much weight, it can be associated with diabetes. Again, there's a test for that. With any treatment, one must weigh the risks and benefits. ...Read more

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I take Depakote for my bipolar 2 disorder will taking a mix of creatine and arginine have any side effects?

Why: Not sure why you would be taking arginine and creatine. Frolic acid and omega 3 supplementation are helpful. Any combination of medications prescribed or otc should be used with caution. Make sure you tell your doctor about all therapeutic substances you are taking so they can help monitor your mood and/or control of seizures depending on why you are taking depakote. ...Read more

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Discontinued Depakote after 20 yrs (seizure-free plus side-effects). Now anxious. I think because of gaba. Don't want benzos. Other ways to increase?

Discontinued Depakote after 20 yrs (seizure-free plus side-effects). Now anxious. I think because of gaba. Don't want benzos. Other ways to increase?

Gabapentin : There are other anti- seizure medications that might be more tolerable for you than Depakote that are also not benzodiazepines. Gabapentin (brand is neurontin) and its newer cousin, prefab akin (brand is lyrica) work on gaba and can be helpful for anxiety (off-label). Talk to your doctor about whether either of these might be appropriate choices for you. ...Read more

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Topamax, (topiramate) Sodium Valproate, Depakote and Lamictal, which are best for migraine aura, and which have the most side effects?

Topamax, (topiramate) Sodium Valproate, Depakote and Lamictal, which are best for migraine aura, and which have the most side effects?

Migraine: Prophylaxis with either Topamax (topiramate) or Depakote would be considered first line aggressive therapy (for males). With Depakote (sodium divalproate) we often see weight gain and a fine tremor (especially in older adults). With Topamax (topiramate) there are more side effects (weight loss, parasthesias, change in sense of taste, inability to sweat, glaucoma, kidney stones ) www.healthtap.com/drericweisman ...Read more

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What are the side effects of taking divalproex drugs?

What are the side effects of taking divalproex drugs?

Depakote side effect: Divalproex is metabolized to valproic acid which can cause stomach upset. Higher doses can be associated with weight gain and tremors. The benefits for patients with bipolar, migraines and seizures are greater than most side effects pts have. I often will use lower doses to keep side effects down and add an additional med such as lithium to boost the benefits. ...Read more

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Which has less side effects specially hair loss divalproex 500mg or topiramate 25 mg?

Which has less side effects specially hair loss divalproex 500mg or topiramate  25 mg?

Topiramate: Topiramate has a lower side effect profile. Howerver, divalproex may be more effective depending on the condition being treated. ...Read more

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I know Depakote has a side effect of severe weight gain what is the percentage rate of people who have gained weight while taking it?

Dpk: I use departed a lot but probably less than I should due to weight gain. Most people don't gain weight on it, esp if they eat exactly the same on it than they ate off it. But my crude estimate would be 40% of people do. Sometimes those it is being used in are predisposed to the weight gain with little activity level or attention to food intake. 40% is my opinion, not from trials. ...Read more

Depakote (Definition)

Depakote is the brand name for a medication known as valproic acid. It is most commonly used to treat seizures, though it can also be used as a mood stabilizer in certain psychiatric disorders. It is used to treat multiple seizure types and can be used alone or with other seizure medications if needed. Common side effects include nausea, dizziness, ...Read more


Anticonvulsant (Definition)

Epileptic seizures, either generalized or focal. Numerous meds are available these days, and some work better with certain types, such as myoclonic or complex partial seizures. Often, in resistant cases, the meds can ...Read more