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Doctor insights on: Wellbutrin Sleep

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My husband is on wellbutrin and sleeping pills, has sleep apnea, and is terrribly volital with temper. Dr. Wants to add Abilify (aripiprazole) but insurance wants ge?

My husband is on wellbutrin and sleeping pills, has sleep apnea, and is terrribly volital with temper. Dr. Wants to add Abilify (aripiprazole) but insurance wants ge?

Geodon (ziprasidone) depression: Geodon (ziprasidone) was tested for use as an augmenting agent and it failed the clinical trial. Have your doctor tell the insurance company that Geodon (ziprasidone) is not approved for that use. Abilify is approved. Best wishes. Btw, they cannot make you use an unapproved medication for any given condition ...Read more

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Dr. Alan Ali
780 doctors shared insights

Bupropion (Definition)

Also called wellbutrin (bupropion) or zyban or aplenzin, is an atypical antidepressant & smoking cessation aid, which has mild psychostimulant action. It is a norepinephrine/dopamine reuptake inhibitor. It can lower seizure threshold at high doses, ...Read more


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I was diagnosed with severe depression. put on colotopin, wellbutrin (bupropion) and a sleep anti depressant. it helped out tremendeously! i no longer have he?

I was diagnosed with severe depression.  put on colotopin, wellbutrin (bupropion) and a sleep anti depressant.  it helped out tremendeously!   i no longer have he?

Not sure: Unfortunately, I am not sure what you are asking. I am glad that your medications have been helpful. I think that you are asking if you should stop them now that you feel better. If this is your question, I would say NO!! You are probably feeling better because of the meds and when and how you stop taking them involves a decision between you and your doc. Discuss before acting . ...Read more

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Wellbutrin (bupropion) isn't letting me sleep! what should I do to get my needed 8 hours?

Wellbutrin (bupropion) isn't letting me sleep! what should I do to get my needed 8 hours?

What time of day are: You taking it? If you are taking one dose - it should be in am. If you are taking a split dose of wellbutrin (bupropion) sr - recommend that the second dose be before 3 pm. If not helping tell your doctor. Retire ; rise same time each day. Keep bedroom dark ; cool ; use only for sex ; sleep. Turn off tv. No naps. Exercise regularly but not in late evening. No caffeine for 6 hrs prior to sleep. ...Read more

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I take Wellbutrin (bupropion) XL 150. Can I take 5HTP at night for sleep?

I take Wellbutrin (bupropion) XL 150. Can I take 5HTP at night for sleep?

No: Taking 5-HTP along with medications for depression might cause serious side effects. Do not take 5-HTP if you are taking medications for depression. ...Read more

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I've been taking Wellbutrin (bupropion) XL 300mg for several weeks and have noticed an increased frequency of hypnic jerks just before sleep. Is this a bad sign?

I've been taking Wellbutrin (bupropion) XL 300mg for several weeks and have noticed an increased frequency of hypnic jerks just before sleep.  Is this a bad sign?

Not bad, but...: It's not bad. It is a possible side effect of bupropion. But it may be intolerable. You will probably wish to change to a different medicine. Why not discuss this with your prescribing doctor? ...Read more

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How can I wean myself from wellbutrin (bupropion) 150xl? Have only been on it for 2 months. I can't sleep and feel jittery.

How can I wean myself from wellbutrin (bupropion) 150xl?  Have only been on it for 2 months.  I can't sleep and feel jittery.

Over a week or two: There are no hard and fast rules regarding stopping medicines such as wellbutrin (bupropion). There is not a life threatening withdrawal syndrome. You can simply halve the dose, see how you feel for a few days, then halve it again, and so on. Be sure you are in contact with your doctor. ...Read more

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I am taking wellbutrin (bupropion) and I am about a week into it and for the part few nights i cannot sleep. Wide awake. Will this go away in time?

I am taking wellbutrin (bupropion) and I am about a week into it and for the part few nights i cannot sleep. Wide awake. Will this go away in time?

Wellbutrin (bupropion): Possible if high dose or dose increase or taken late in the day. Review with your prescribing doc. ...Read more

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My wife told me that my body shakes during the night and i wake her up. Do you know how i could be shaking during sleep? I'm taking 150 mg wellbutrin (bupropion)

My wife told me that my body shakes during the night and i wake her up.  Do you know how i could be shaking during sleep? I'm taking 150 mg wellbutrin (bupropion)

Possibilities: Some sleep disorders result in movements while asleep such as paroxysmal leg movements in sleep (noctournal myoclonus). Welbutrin can cause seizures as an adverse event in some. You may benefit from a sleep study overnight. ...Read more

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I sweat so bad when I sleep I wake up soaked? It seems to be getting worse, I take wellbutrin & cymbalta (duloxetine)? Is this something I should be worries about?

I sweat so bad when I sleep I wake up soaked? It seems to be getting worse, I take wellbutrin & cymbalta (duloxetine)? Is this something I should be worries about?

Soaked: Yes, you should be worried about this. Please don't change your medicines for now but get a clinic visit to your doctor as soon as possible. Please let me know how things go. ...Read more

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Can i take nyquill sleep aid with wellbutrin (bupropion)?

Ask U PCP: He needs to know what u taking since all medication can have side effect , and may be he has a better choice. ...Read more

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Taking wellbutrin (bupropion) 150mg, want to know if taking Traizodone 50mg to sleep is okay. i cant sleep and sleep hygiene is not the problem. ?

Taking wellbutrin (bupropion) 150mg, want to know if taking  Traizodone 50mg to sleep is okay.  i cant sleep and sleep hygiene is not the problem. ?

Seizure risk: This is a risky combo. Definitely discuss alternatives w/ your provider. Especially for anyone w/ other medical issues or weaknesses (i.e., elderly) this can increase intensity of all other side effects. Discuss. Find another choice. ...Read more

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On wellbutrin 150 sr generic for 1 week. my anxiety is very high and im irritable and cant sleep. dr. says it will go away? also afraid of wgt gain?

On wellbutrin 150 sr generic for 1 week.  my anxiety is very high and im irritable and cant sleep. dr. says it will go away?  also afraid of wgt gain?

Side effects?: What lead you to be on Welbutrin in the first place? How long have you hi-anxiety, irritable & can't sleep? Have you consider alternatives; Yoga, meditation, regular exercise? Are you on or a candidate for HRT? What else is going on in your life? How long are you willing to put up with these before "it will go away"? Think, you may have more answers than I, the doctor, in this matter. ...Read more

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I just started taking Wellbutrin 100mg every 12 hours 4 months ago and Adderall XR 10mg starting today and I can't sleep can I take Benadryl 25mg?

I just started taking Wellbutrin 100mg every 12 hours 4 months ago and Adderall XR 10mg starting today and I can't sleep can I take Benadryl 25mg?

Med combo.: Talk with your prescribing physician about your insomnia. Wellbutrin can be stimulating. I usually recommend my patients take doses around 8 hours apart so that the second dose is not in the evening. Adderall is a stimulant - so recommend taking it early in the morning. Benadryl can be used with this. Also used good sleep hygiene. ...Read more

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I increased my wellbutrin from 75 to 150mg and lowered my Paxil (paroxetine) from 20 to 15mg. I don't feel like my sleep is restful anymore and i'm exhausted?

I increased my wellbutrin from 75 to 150mg and lowered my Paxil (paroxetine) from 20 to 15mg. I don't feel like my sleep is restful anymore and i'm exhausted?

Dose timing: I agree with dr. Maes about making medication changes along with your physician, rather than all alone. What time are you taking your wellbutrin (bupropion)? It can be activating, and could disrupt your sleep if taken at bedtime. Please discuss any changes you want to make with your doctor -- s/he's there to be on your healing team with you. ...Read more

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Wellbutrin xl. Can u take 150 ml of bupropion in the morning. And 10 ml of elavil (amitriptyline) at night for sleep?

Wellbutrin xl. Can u take 150 ml of bupropion in the morning. And 10 ml of elavil (amitriptyline) at night for sleep?

Yes: But sometes people get used to the sedating side effects of Elavil (amitriptyline) so that is why it is not approved as a sleep med. The is no reason why the two meds can not be taken. They are comparable ...Read more

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I take klonopin .5 a day and Wellbutrin (bupropion) 150mg twice a day I can't sleep is it safe to add doxylamine succinate aka unisom with that mix?

I take klonopin .5 a day and Wellbutrin (bupropion) 150mg twice a day I can't sleep is it safe to add doxylamine succinate aka unisom with that mix?

Drug interactions: Doxylamine is an antihistamine which may interact with Klonopin (clonazepam) to increase side effects such as dizziness, drowsiness or difficulty concentrating. Limit or avoid use of alcohol and avoid driving until you know how this combination of medications affect you. Discuss with your prescribing doctor before taking Unisom. Take care. ...Read more

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I currently take lamictal 10mg, Prozac 20 mg, Latuda (lurasidone) 20mg, vyvanse 70mg, and Wellbutrin 300mg but can't sleep still?!?! And mood are all over still.

I currently take lamictal 10mg, Prozac 20 mg, Latuda (lurasidone)  20mg, vyvanse 70mg, and Wellbutrin 300mg but can't sleep still?!?! And mood are all over still.

When do you take?: Diagnosis? Lamictal and latuda (lurasidone) for mood stabilization? Both are subtherapeutic dose. Prozac and Wellbutrin are antidepressants and may increase mood variability. Vyvanse is stimulant. Bipolar d/o and ADD overlap as far as symptoms, but rare to have both and treatment very different. All but latuda (lurasidone) can be stimulating and should be taken in am. Please discuss with prescribing doc. ...Read more

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Iam bp1 on 2 sleep meds ativan Abilify (aripiprazole) Zoloft lithium wellbutrin ...Dr is taking some away and. I'm stil having up n downs as a dr would u remove meds?

Iam bp1 on 2 sleep meds ativan Abilify (aripiprazole) Zoloft lithium wellbutrin ...Dr is taking some away and. I'm stil having up n downs as a dr would u remove meds?

Yes: I don't know your history, but it's rare to require so many different drugs. The fewer the better, right? Or at least lower doses. You might be really tired to be on so many meds. However, each med does help with slightly different things, so it's possible to take them all, just far from ideal. ...Read more

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Severe health anxiety and depression. CBT and Wellbutrin (bupropion) and Lexapro not working. Can't sleep , can't stop worrying. What can I do ? Life stinks .

Regulation of habits: Besides the CBT, Wellbutrin (bupropion) & Lexapro try a notebook or tablet to track your daily routines like diet, sleep, regular meals, 7-9, 11-1, 5-7, enough sleep, exercise, dietary intake (calories), meditation, relaxation exercises, tai-chi, martial arts, prayer, anything that will help light up the frontal lobes if we would scan yours. It will take some time but all of the above will work over time. ...Read more

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Dr. Heidi Fowler
4,978 doctors shared insights

Sleep (Definition)

Sleep is a topic that involves concepts such as how long it takes to fall asleep, how many times one wakes up at night, how many hours one sleeps at night, sleep stages, ...Read more


Wellbutrin (Definition)

Bupropion is an addiction reducing agent and an antidepressant which are both a ...Read more