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Doctor insights on: Wellbutrin Ocd

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My son, 18, is taking 80 mg of Prozac and 75 mg of Wellbutrin for OCD. He is relapsing. He has been on this for two years. What are some choices?

My son, 18, is taking 80 mg of Prozac and 75 mg of Wellbutrin for OCD. He is relapsing. He has been on this for two years. What are some choices?

Decisions: 18 is a challenging age. Your son can consent for treatment as he is of age. Important to clarify whether or not he is still taking his meds as many teens stop when they are of consenting age. Cognitive behavioral therapy is also an effective form of treatment for OCD either alone or in conjunction with meds. Follow up with psychiatrist for any changes in medication, additional therapies. ...Read more

Dr. Alan Ali
789 Doctors shared insights

Bupropion (Definition)

Also called wellbutrin (bupropion) or zyban or aplenzin, is an atypical antidepressant & smoking cessation aid, which has mild psychostimulant action. It is a norepinephrine/dopamine reuptake inhibitor. It can lower seizure threshold at high doses, ...Read more


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Adding a dopamine medication such as latuda/wellbutrin to an ocd/bipolar patient--wouldn't this make the OCD worse?

Adding a dopamine medication such as latuda/wellbutrin to an ocd/bipolar patient--wouldn't this make the OCD worse?

Not really.: Latuda (lurasidone) is an antipsychotic. Sometimes ocd is so severe that it reaches psychotic proportions, that Latuda (lurasidone) can help. But it is not indicated for ocd itself. Wellbutrin is an antidepressant of the aminoketone group, a Dopamine agonist and norepinephrine reuptake inhibitor. It is not indicated for ocd but may help the depression in ocd. Neither drug can make ocd worse. ...Read more

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What medication can be combined with wellbutrin (bupropion) to treat ocd and anxiety?

What medication can be combined with wellbutrin (bupropion) to treat ocd and anxiety?

Quite a few: There are quite a few medicines across multiple classes (SSRI, SNRI, TCA, etc.) that can be added however Rx choice really depends on what symptoms need the "extra help." The goal is to reduce the risk of side effects as much as possible and a lot is dependent on your history/response and prescriber preference. Also, combining psychotherapy + meds helps ensure a better outcome. Hope that helps! ...Read more

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Can I take luvox for ocd and wellbutrin (bupropion) for antidepressant?

Can I take luvox for ocd and wellbutrin (bupropion) for antidepressant?

It is possible but..: Yes they both work in the body differently so in some cases it can be a good combination with Luvox (fluvoxamine) being effective for ocd and depression and Wellbutrin
being an antidepressant that works differently than the Luvox (fluvoxamine). However, they both can cause side effects and it is possible that in some cases they could magnify each others side effects. So you need to go slowly with the guidance of your doctor ...Read more

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Is there any supplements to help a male experiencing no sex drive on 10mg Lexapro and 150mg wellbutrin (bupropion) XL for ocd/anxiety?

Is there any supplements to help a male experiencing no sex drive on 10mg Lexapro and 150mg wellbutrin (bupropion) XL for ocd/anxiety?

Female sex cream: Apricus biosciences is currently developing the product femprox, a topical cream for the treatment of female sexual arousal disorder. It contains prostaglandin e1 as the active ingredient and a permeation enhancer ddaip which facilitates the delivery of the drug into the blood stream. An existing drug, bremelanotide, has also been found to increase libido in 90% of subjects. ...Read more

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Wellbutrin (bupropion) has always helped with my OCD and anxiety. It seems the opposite for others. Do you think my external factors really made symptoms better?

Wellbutrin (bupropion) has always helped with my OCD and anxiety. It seems the opposite for others. Do you think my external factors really made symptoms better?

Maybe.: Wellbutrin has caused anxiety in some depressed people but if it helps your ocd, continue to take it. There are other antidepressants well known to help ocd such as luvox, anafranil, zoloft, Pristiq (desvenlafaxine), Lexapro but each individual is different. The poor concentration makes me think that you may have symptoms of attention deficit for which wellbutrin is indicated. ...Read more

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Does wellbutrin (bupropion) help social anxiety and ocd?

Does wellbutrin (bupropion) help social anxiety and ocd?

No, not so much: Wellbutrin (bupropion) does not have much in the way of anti-anxiety or anti obsessional effects. Other medications, often ssri antidepressants work much better for this. Psychiatrists can help you find a helpful one -- evaluation first, though! ...Read more

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Will taking wellbutrin (bupropion) with Lexapro help OCD and intrusive thoughts without making me gain weight?

Will taking wellbutrin (bupropion) with Lexapro help OCD and intrusive thoughts without making me gain weight?

Probably not: Wellbutrin (bupropion) will probably not make you gain weight -- but it's also unlikely to help with ocd and intrusive thoughts. Others like ssri's (like lexapro) are much better for ocd, and some are more weight-neutral (lexapro) than others. See a psychiatrist for an evaluation and discussion of options. ...Read more

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Taking 300mgs wellbutrin (bupropion) but suffering from my ocd. Can I go back on my Luvox to address the ocd and anxiety as it has worked well for me.

Taking 300mgs wellbutrin (bupropion) but suffering from my ocd. Can I go back on my Luvox to address the ocd and anxiety as it has worked well for me.

Interaction: Best to discuss this with your prescribing physician. There is a potential for an interaction to occur with these 2 medications but that likelihood is lowered since you've had success with this combo in the past. Hope that helps! ...Read more

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Can Luvox and Wellbutrin (bupropion) be used together to treat depression and ocd?

Can Luvox and Wellbutrin (bupropion) be used together to treat depression and ocd?

Depression, OCD: I feel empathy for your depression and OCD.
Luvox helps with depression and OCD.
Wellbutrin helps with depression.
These medications benefit intense symptoms
They do not take care of the stresses which are causing depression and OCD.
Do not become victim of your depression and OCD.
Do not focus on symptoms.
Feel good about your functioning.
See a Psychiatrist for Intensive Therapy, Medication. ...Read more

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Can wellbutrin and effexor (venlafaxine) go together to help GAD, OCD, and depression?

Can wellbutrin and effexor (venlafaxine) go together to help GAD, OCD, and depression?

Sure: This is a fairly standard cocktail for depressive and anxiety disorders. While I prefer the newer version called Pristiq (desvenlafaxine) (because you don't need to titrate the dose like Effexor XR). .. That's more a matter of physician preference, hope that helps! ...Read more

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Is wellbutrin and effexor (venlafaxine) a good combination to treat GAD, OCD, and depression?

Is wellbutrin and effexor (venlafaxine) a good combination to treat GAD, OCD, and depression?

Everyone is diff.: Not all folks will respond the same. However this combination has been tried in so many people in the best with great results. If the symptoms worsen or noticeable side effects then follow up sooner. However many people get good response on this. ...Read more

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Is luvox and wellbutrin (bupropion) a safe combo in treating ocd, anxiety and depression?

Is luvox and wellbutrin (bupropion) a safe combo in treating ocd, anxiety and depression?

Alternative: These meds. Have the possibility of interacting with each other (although this can be minimized by starting with a low dose). That said, there are safer alternatives. Personally, I tend to try Pristiq (desvenlafaxine) + Wellbutrin XL for patients who aren't doing well on an SSRI alone. But this is a matter of prescriber preference and what your physician feels is the most appropriate for you. Hope that helps! ...Read more

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Dr. Recently prescribed me wellbutrin (bupropion) and zoloft for my ocd and depression. Is this combo safe?

Yes: Wellbutrin (bupropion) can raise your blood pressure in doses above 300mg. If you have an eating disorder or alcoholism it can lower your threshold to have a seizure. Otherwise the combo is safe relatively. ...Read more

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Hello I am on a high dose of citalopram 80mg for OCD, seen improvement in OCD not depression. Would adding Wellbutrin (bupropion) help?

Hello I am on a high dose of citalopram 80mg for OCD, seen improvement in OCD not depression. Would adding Wellbutrin (bupropion) help?

Need more info: Impossible to answer this question not knowing your medical & psychological history. Much better to talk it over with the physician who prescribed citalopram. ...Read more

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My ocd, depression and anxiety has been terrible. Dr prescribed wellbutrin (bupropion) and luvox. I want to get well but also want to be sure this combo is safe?

My ocd, depression and anxiety has been terrible. Dr prescribed wellbutrin (bupropion) and luvox. I want to get well but also want to be sure this combo is safe?

OCD, Depression,: I commend you for being concerned about your Health!
Luvox (fluvoxamine) helps with depression, anxiety and OCD.
Wellbutrin helps with depression.
Both have side effects.
Provide history to your Psychiatrist about severity of all these conditions, effect on functioning in your relationships, work and daily life; discuss if you can take Luvox (fluvoxamine) at this time and have Intensive Therapy, Breathing Relaxation, Yoga. ...Read more

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On for ocd 200 mgs of zoloft added wellbutrin (bupropion) 200 mgs. I was wondering if risperidone in a low dose would be better as an add on than wellbutrin (bupropion)?

Very different: At the level of Zoloft you are using, any medication changes should be made after consultation with a qualified practitioner. Rispridone is VERY different than wellbutrin (bupropion). ...Read more

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What are the risks of taking wellbutrin (bupropion) and Zoloft long term? Being used to treat ADHD and OCD respectively

What are the risks of taking wellbutrin (bupropion) and Zoloft long term? Being used to treat ADHD and OCD respectively

Not clear: There is conflicting data regarding use of antidepressants later in life and all cause mortality although there is the notion that the medications are relatively benign. There is always going to be a risk benefit analysis that is necessary in addition to the number needed to treat or a number needed to harm with any medication reflecting the capacity to do both good and bad things to patients. ...Read more

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I'm on 80mg of Prozac, 150 mg of seroquil, 10mg brintellex and Wellbutrin (bupropion) 100mg twice a day for depression and OCD. My np doesn't want to change any.

I'm on 80mg of Prozac, 150 mg of seroquil, 10mg brintellex and Wellbutrin (bupropion) 100mg twice a day for depression and OCD. My np doesn't want to change any.

Not effective?: Need more information to understand your primary concern - is your concern the regimen is not effective, or too much? Or is your concern with the regimen itself? In general I encourage keeping an open line of communication with your provider. If your concerns remain or regimen is ineffective, a second-opinion consult may help to explore treatment options further. Be well. ...Read more

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What is the best medicine for OCD. We have tried Zoloft, lexapro, wellbutrin, prozac. Side effects bad or did not work. Does Pristiq (desvenlafaxine) work for OCD?

What is the best medicine for OCD. We have tried Zoloft, lexapro, wellbutrin, prozac. Side effects bad or did not work. Does Pristiq (desvenlafaxine) work for OCD?

SSRI's failed: So one SSRI may work when another does not. Keep trying. There is a new one called Brintillex which has much greater effectiveness in the reported studies.
Also a Selegeline patch may prove effective. ...Read more

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17 yr old male. Had depression. Anxiety and ocd. He's on Zoloft and wellbutrin. Would it be wise to try pristiq (desvenlafaxine)?

Not necessarily: Pristiq (desvenlafaxine) is a seratonin reuptake inhibitor such as Zoloft., so it does not necessarily have more to offer than Zoloft. ...Read more

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I think I'm bipolar, is wellbutrin the best medication for me? After a lifetime of serious emotional problems, I'm finally ready to admit that I'm probably bipolar. I'm also ocd, have severe depression and anxiety. I'm almost 60 years old and only now am

Time to act: It sounds you have been suffering for a long time. Ocd can happen at the same time with bipolar disorder. And they are treatable. If you have bipolar type ii, it is easily mistook for major depression. Going back to the drawing board with your psychiatrist and look at all the symptoms as a whole will help you reevaluate your treatment and set it on a better course. Now that you admit the problem. ...Read more

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Is a combination of 60mg of prozac and 150mg of wellbutrin xl effective for depression, anxiety, and obsessive compulsive disorder?

Is a combination of 60mg of prozac and 150mg of wellbutrin xl effective for depression, anxiety, and obsessive compulsive disorder?

For some people: This type of treatment has to be individualized for each person. Wellbutrin is good for depression but could make anxiety worse in some patients. Prozac is good for all three disorders in most people.. ...Read more

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Benefits and disadvantage of sertraline&bupropion combine? (in ocd+mdd, please don't describe singly), best regards to doctors who will give us better life.

Benefits and disadvantage of sertraline&bupropion combine? (in ocd+mdd, please don't describe singly), best regards to doctors who will give us better life.

Good combination: Sertraline and bupropion combination is a common combination for treatment of resistent depression. Sertraline works on serotonin system in brain and bupropion works on adrenergic system and the two work synergistically to help you. Bupropion also help negate some of the side effects of sertraline like sexual side effects. ...Read more

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According to the anxiogenic potential of bupropion, can lead OCD to get worse? When I was on just sertraline I was better than now, bup&sert combine.

According to the anxiogenic potential of bupropion, can lead OCD to get worse? When I was on just sertraline I was better than now, bup&sert combine.

Can be used: During the course of treatment of ocd, depressive symptoms including poor energy and motivation may arise, buproprion is cautiously added to an ssri and in small dosages, we try to strike a balance between both meds, often we increase dosage of ssri, or add augmentation., in brief, there are several strategies to address the arising depression during ocd treatment, please check with ur dr. ...Read more

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Combining bupropion with sertraline lead my OCD worse? Mdd and sleepiness is ok. Regards

You & ur Doc: Who prescribed you sertraline & bupropion have to discuss together your current medication regimen. Ocd worse has 2 b evaluated while mdd & sleepiness r improved. A follow-up face 2 face consultation & exam r needed w/the doc who prescribed ur meds. Pls make appt & talk 2 her/him, s/he will continue 2 help u. Take care & best wishes. ...Read more

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Is there an OCD or anti anxiety med that will not put me to sleep so much? I tryed paxil, (paroxetine) wellbutin, elavil, but could not stay awake. Knocks me out.

Is there an OCD or anti anxiety med that will not put me to sleep so much? I tryed paxil, (paroxetine) wellbutin, elavil, but could not stay awake. Knocks me out.

Try few others: Surprisingly, medicine within same class may have totally difference side effects. Elavil is highly sedating to many. You may try cymbalta, (duloxetine) prestiq or luvox. You many have luck with another ssris, such as Lexapro or prozac. ...Read more

Wellbutrin (Definition)

Bupropion is an addiction reducing agent and an antidepressant which are both a ...Read more