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Doctor insights on: Wellbutrin Addiction Reducing Agent

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Does caffeine reduce the effect of psychotropic drugs? Particularly Effexor, Buspar, (buspirone) Trazodone, and Topamax.

Does caffeine reduce the effect of psychotropic drugs? Particularly Effexor, Buspar, (buspirone) Trazodone, and Topamax.

No interaction but..: I ran the interaction checker and there is no known interaction between caffeine and any of the meds you mentioned. However, it is well known that caffeine disrupts sleep patterns and can increase anxiety either on it and while withdrawing from it. Therefore, it is best to cut caffeine to a very minimum ...Read more

Dr. Vasu Brown
612 doctors shared insights

Addiction (Definition)

Addiction is a primary, chronic disease of brain reward, motivation, memory, and related circuitry. Dysfunction in these circuits leads to characteristic biological, psychological, social and spiritual manifestations. This is reflected in an individual pathologically pursuing reward and/or relief by substance use and other behaviors. A person affected by addiction will be unable to consistently Abstain from use, will have Impaired Behavioral control, will have Craving or increased "hunger" for drugs or rewarding experiences, will have a Dysfunctional Emotional response, and will show diminished recognition of significant problems with their own ...Read more


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Which ssri/ anxiety/depression med lowers libido?

Which ssri/ anxiety/depression med lowers libido?

All: Most all antidepressants can affect a person's normal sexual functioning at various different levels and in different ways. The antidepressants which affect serotonin can cause problems with the ability to have an orgasm. The one antidepressant which has the lowest risk for sexual side-effects is called buproprion or wellbutrin (bupropion). ...Read more

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Is wellbutrin (bupropion) a dopamine agonist drug?

Is wellbutrin (bupropion) a dopamine agonist drug?

Mostly: Wellbutrin (bupropion) interferes with reuptake of dopamine&norepinephrine(noradrenaline)in the central nervous system, thereby leaving these neurotransmitters to sit longer&stronger in the synapse between communicating brain cells, which enhances dopamine&adrenaline activity at the cellular level. That can treat depression, feed pleasure to help sex&bypass tobacco, improve adhd&cognition, lower weight, etc. ...Read more

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Only noradrenergic antidepressant works for me, does inderal (propranolol) acts negative on noradrenergic effects of antidepressant ?At vasomotor centers.Regards.

Only noradrenergic antidepressant works for me, does inderal (propranolol) acts negative on noradrenergic effects of antidepressant ?At vasomotor centers.Regards.

Venlafaxine: It's not the vasomotor centers that are important in antidepressant response; it's the neuron synapses in the brain. Effexor (venlafaxine) inhibits reuptake of both serotonin and ne. Inderal can suppress some of the physical symptoms of anxiety (rapid heart rate, sweaty palms, tremulousness, etc). Some on chronic (not intermittent or "prn") Inderal have had more depression. Not everyone. You should be okay. ...Read more

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Is buproprion a monoamine oxidase inhibitor (maoi) type of drug?

Is buproprion a monoamine oxidase inhibitor (maoi) type of drug?

No: Bupropion (wellbutrin) inhibits re-uptake of norepinephrine and Dopamine into neurons (nerve and brain cells). It does not inhibit mao, so there are no dietary restrictions or common medication interactions, unlike the the maois. ...Read more

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Is zoloft's dopaminergic effect dose dependant like effexor's noradrenalinergic effect?

Is zoloft's dopaminergic effect dose dependant like effexor's noradrenalinergic effect?

Zoloft (sertraline): Yes it is. Dopamin reuptake inhibition increases as dose increase. ...Read more

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Bipolar(controlled -lamictal, carbamazepine), anxiety-semi-under control (lorazepam, temazepam, cymbalta) and ADD problematic- considering Vyvanse (lisdexamfetamine) ?

Bipolar(controlled -lamictal, carbamazepine), anxiety-semi-under control (lorazepam, temazepam, cymbalta)  and ADD problematic- considering Vyvanse (lisdexamfetamine) ?

So much medication: It might be necessary to take some drugs but I question the risks already and adding the new one is especially bad w/ cymbalta (duloxetine). It can cause severe anxiety! Also serotonin syndrome. Almost all of your meds combine to cause a host of symptoms like dizziness, confusion and general impairment. Please consider a good psych eval and adding good psychotherapy to lower need for Rx and help them work! ...Read more

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Is viibryd (vilazodone hydrochloride) an effective medication for anxiety?

Is viibryd (vilazodone hydrochloride) an effective medication for anxiety?

Yes: Viibryd (vilazodone hydrochloride) is a new class of antidepressant. I have found it useful for anxiety as well as depression. It has different side effects than the others so might benefit people who didn't tolerate others well. No weight gain and maybe less sexual dysfunction, but can cause a lot of nausea and diarrhea and must be taken with food. ...Read more

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Is Vyvanse and wellbutrin (bupropion) XL combo effective for treating ADHD (primarily inattentive) and major depression? Could this combo lower seizure threshold?

Is Vyvanse and wellbutrin (bupropion) XL combo effective for treating ADHD (primarily inattentive) and major depression? Could this combo lower seizure threshold?

Yes and Yes...: Vyvanse is an excellent medication for adhd just as wellbutrin (bupropion) is and excellent medication for depression. Wellbutrin (bupropion) can be assoicated with seizures and should not be prescribed to those with a seizure disorder or lowered seizure threshold. ...Read more

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What meds, other than wellbutrin, (bupropion) can increase the dopamine re~uptake inhibitors?

What meds, other than wellbutrin, (bupropion) can increase the dopamine re~uptake inhibitors?

Several: Levodopa, which is used to treat parkinson's, encourages the brain to make dopamine. Tyrosine, an Amino Acid made from phenylalanine, is converted into levodopa, which is in turn converted to dopamine. Wellbutrin (bupropion) & the maoi's can also increase dopamine. Most tca's have minimal affinity for dat and thus don't increase Dopamine levels. Periwinkle and st. John's wort may also increase dopamine. ...Read more

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Tried ssri/xanax for depression/anxiety, bad reactions. I heard wellbutrin (bupropion) works on different brain chemicals than ssri's. Can wellbutrin (bupropion) help?

Tried ssri/xanax for depression/anxiety, bad reactions. I heard wellbutrin (bupropion) works on different brain chemicals than ssri's. Can wellbutrin (bupropion) help?

Wellbutrin (bupropion): Wellbutrin does work on different neurotransmitters than SSRI's - specifically norepinephrine and dopamine. That said, you mentioned using Xanax (alprazolam) in the past - and Wellbutrin does have an "activating" effect for many people. So, it's probably not the best option for you. I'd suggest seeing a psychiatrist to talk over all of the options available (sometimes dosing is the key). Good luck! ...Read more

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Is the combo (Wellbutrin (bupropion) XL150mg+Buspirone60mg) instead of SSRI the best alternative to treat GAD and decrease the sexual dysfunctions caused by SSRI?

Maybe: Because each person's chemistry is different, there are many combinations that might work. I assume you and your doctor have discussed and/or tried other combinations. If this is working, keep using it. If not, discuss the results with your doctor. ...Read more

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How sertraline effects methylphenidate metabolism?Can be used to increasing ritalin half life?Best regards.

How sertraline effects methylphenidate metabolism?Can be used to increasing ritalin half life?Best regards.

No: Sertraline does not affect the metabolism of methylphenidate and vice versa. Some unproven but helpful ways to decrease tolerance to stimulants are with magnesium or with memantine. ...Read more

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Marijuana plus ssri. Bad combination? The ssri is a follow up to nicotine deaddiction medication.

Marijuana plus ssri. Bad combination? The ssri is a follow up to nicotine deaddiction medication.

Bad combination: Sounds like you're still in an addiction pattern, if still using marijuana. And yes, this is a bad combination if you want to end your addictive behavior. ...Read more

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Does wellbutrin (bupropion) decrease your impulsivity?

Depends: Wellbutrin (bupropion) has been used by some people as a type of attention or impulsivity treatment though this isn't it's original intention or indication. It might be worth a try depending on your other symptoms. ...Read more

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How can a medication like cymbalta (duloxetine) which raises norepinephrine help with anxiety as Cymbalta (duloxetine) is approved for general anxiety at 60 mg.?

How can a medication like cymbalta (duloxetine) which raises norepinephrine help with anxiety as Cymbalta (duloxetine) is approved for general anxiety at 60 mg.?

Norepinephrine: Norepinephrine is one of the neurotransmitters involved in attention, pain perception, heart rate, activation of the "fight or flight" system, and many others. Cymbalta (duloxetine) is a weak NE reuptake inhibitor ... So, in theory, it keeps more NE from being recycled out of the brain. By keeping more NE, the effects of anxiety on the body are decreased (theoretically). Hope that helps & good luck! ...Read more

Dr. Alan Ali
789 doctors shared insights

Bupropion (Definition)

Also called wellbutrin (bupropion) or zyban or aplenzin, is an atypical antidepressant & smoking cessation aid, which has mild psychostimulant action. It is a norepinephrine/dopamine reuptake inhibitor. It can lower seizure threshold at high doses, ...Read more


Wellbutrin (Definition)

Bupropion is an addiction reducing agent and an antidepressant which are both a ...Read more