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Doctor insights on: Wegeners Granulomatosis Blood

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Causes of wegeners granulomatosis and treatment?

Causes of wegeners granulomatosis and treatment?

Autoimmune disease: Like all autoimmune diseases, the cause is not really known, but likely a combination of genetic factors and environmental exposures (e.g., infections, chemicals, pollutants). Treatment depends on how severe disease it is. Typically steroids (e.g. Prednisone) and if severe, Cytoxan or rituxan (rituximab). If limited disease (just nasal/upper airway involvement), Methotrexate may be sufficient. ...Read more

Dr. Al Hegab
30 doctors shared insights

Granulomatosis (Definition)

A process associated with a tissue reacton involving monocytes and tissue macrophages. Clasically this was seen in infections, like tuberculosis and some fungal processes. It is also seen and inflammatory and reactive ...Read more


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Has anyone ever heard of the disease wegeners granulamatosis?

Has anyone ever heard of the disease wegeners granulamatosis?

Yes: Wegener's granulomatosis with polyangiitis is an incurable form of vasculitis (inflammation of blood vessels) that affects the lungs, kidneys, and other organs. Due to its organ damage, it is life-threatening and requires long-term immunosuppression. Five-year survival is up to 87%, with some of the mortality due to toxicity of treatment. Since that is an average figure, some will live longer. ...Read more

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What is the disease wegeners granulamatosis in kids?

What is the disease wegeners granulamatosis in kids?

WG: Wegener’s granulomatosis (WG) is a rare disease that causes the walls of blood vessels to become inflamed (called vasculitis). This limits blood flow to tissues and can affect any organ. WG is a type of autoimmune disease. This means the body’s immune system attacks its own tissues. Its cause is unknown. ...Read more

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What is the definition or description of: granulomatosis?

What is the definition or description of: granulomatosis?

Granulomatosis is : A process associated with a tissue reacton involving monocytes and tissue macrophages. Clasically this was seen in infections, like tuberculosis and some fungal processes. It is also seen and inflammatory and reactive processes such as sarcoidosis. ...Read more

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Can you tell me what wegeners vasculitis?

Can you tell me what wegeners vasculitis?

Serious illness: Wegner's granulomatous angiitis is caused by antibodies against a particular protein in neutrophils. Once uniformly fatal, it is now usually managed with strong medications by specialists. The eyes, ears, throat, lungs and kidneys are the usual targets. Wegener's greatness as a physician is tarnished by his having served the third reich, though not in the death camps; some avoid his name. ...Read more

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Husband diagnosed with wegener's granulomatosis. Will his lung & kidney function return to normal?

Husband diagnosed with wegener's granulomatosis.  Will his lung & kidney function return to normal?

Chance: In the past, wegener's granulomatosis was usually fatal. Currently, we have new and excellent treatment for the disease and some patients with kidney and lung disease have gone into remission. That does not always mean that the lung or kidney function will be completely normal but the disease progression can be stopped in some cases. ...Read more

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How can I live with wegeners disease?

How can I live with wegeners disease?

Vasculitis : Wegeners granulomatosis now known as granulomatosis with polyangiitis is incurable vasculitis that effects the nose , lungs , and kidneys. It requires life long immunosupressant. With treatment five year survival is 87%. ...Read more

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Could you give me information on wegeners ?

Autoimmunity rarity: Wegener's granulomatosis is a rare autoimmune condition that causes inflammation of blood vessels and tissues, usually the nose, mouth, ears, lungs, or kidneys. Untreated it was usually fatal in the past but new treatments have been developed that make this disease treatable. The doctor to see is a rheumatologist. See http://www.mayoclinic.org/diseases-conditions/wegeners-granulomatosis/basics/. ...Read more

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What are symptoms of wegener's granulomatosis?

See details: The most common presenting symptom is a chronic sinusitis but there can be numerous other issues associated with wegener's including arthritis, pneumonia, eye problems, kidney disease and cardiac and neurologic issues. ...Read more

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What are the tests for wegener's granulomatosis?

What are the tests for wegener's granulomatosis?

ANCA and biopsy: The most useful blood test is an anca with titer and pattern, and pr3/mpo confirmation. Biopsy of the affected tissue is also important. Imaging studies of the lungs and sinuses can be useful as well as blood and urine tests looking for kidney damage. Finally, EMG might be needed if there is concern for nerve damage. ...Read more

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Dr. Arthur Balin
32 doctors shared insights

Wegener's Granulomatosis (Definition)

Wegener's Granulomatosis is a medical condition in which the blood vessels supplying the nose, lungs, kidneys and other organs become inflamed. Symptoms include nose bleeds, difficulty ...Read more