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Doctor insights on: Wegener Granulomatosis Emedicine

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What is wegener's granulomatosis vasculitis?

What is wegener's granulomatosis vasculitis?

See details: It is a form of vasculitis effecting medium sized arteries and associated with a positive canca blood test. It usually begins as chronic sinusitis but with time can effect many other organ systems including eyes, heart, kidneys, joints, lungs and the nervous system. There are very effective treatments available. ...Read more

Dr. Michael Gabor
34 doctors shared insights

Wegener's Granulomatosis (Definition)

Wegener's granulomatosis (Granulomatosis with polyangiitis) causes vasculitis ( inflammation blood vessels of nose, sinuses, throat, lungs ...Read more


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What is wegener's granulomatosis?

What is wegener's granulomatosis?

Wegener's: Granulomatosis is an incurable form of vasculitis (inflammation of blood vessels) that affects the nose, lungs, kidneys, and other organs. ...Read more

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What is wegner's granulomatosis?

Serious condition: This is a very rare disease which is a form of vasculitis(inflammation of the blood vasculitis) it commonly causes, sinusitis, has associated lung nodules and is associated with varying degrees of kidney damage which can lead to kidney failures. But it is treatable, usually requiring chemotherapy(although it is not cancerous!). ...Read more

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What's granuloma annulare disease?

What's granuloma annulare disease?

Skin granulomas: Granuloma annulare is a condition where granulomas (little lumps of immune reactive tissue) form in the skin. It can occasionally be associated with thyroid disease or diabetes, so you should be worked up for those conditions by your doctor. Otherwise, it is benign and of only cosmetic concern. Treatment is usually with steroid injections into the granulomas, but other therapies are described. ...Read more

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Does anyone have information about wegener's granulomatosis vasculitis?

Attacks organs: Wegener's granulomatosis (wg), also known as recently granulomatosis with polyangiitis results in inflammation of blood vessels vasculitis. Wg mainly affects nose, lungs, kidneys and other organs. Treatment is long-term immunosuppression to reduce antibodies which are thought to "attack" the medium and small blood vessels. Dr. Friedrich wegener described the disease in 1936. ...Read more

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Is polyarteritis nodosa an autoimmune disease?

Is polyarteritis nodosa an autoimmune disease?

Polyarteritis causes: The answer to your question is "it may be" an auto-immune disorder. Polyarthritis is most often caused by an auto-immune disorder such as rheumatoid arthritis, amyloidosis, psoriatic arthritis, and lupus erythematosus. In addition, it may also be caused by infection with an alphavirus such as chikungunya virus and ross river virus. Ask your physician for more information in your instance. ...Read more

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What's a good description of wegener's granulomatosis vasculitis?

Systemic vasculitis: Wegener's is a systemic vasculitis associated with the presence of specific blood tests known as a canca or pr3 antibodies. It usually presents as chronic sinusitis and more rarely pneumonia but can effect other areas of the body especially the kidneys, eyes, heart and nervous system. It is very serious but newer medications have provided effective treatment in most cases. ...Read more

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Atenolol-induced lupus erythematosus http://www.Ncbi.Nlm.Nih.Gov/pubmed/9270530?

Atenolol-induced lupus erythematosus           http://www.Ncbi.Nlm.Nih.Gov/pubmed/9270530?

Let me explain: I read the article, this medication could induce symptoms of autoimmune disease including lupus, but lupus has no cure to date but those symptoms disappear with the treatment. That the main difference. ...Read more

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Is lupus erythematosus infectious?

Is lupus erythematosus infectious?

No: Is a immune based disease does not recognize self and attacks multiple organs. ...Read more

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What is wegeners vasculitis?

What is wegeners vasculitis?

Disease or Syndrome?: Wegener's granulomatosis (wg), more recently granulomatosis with polyangiitis (wegener's) (gpa), is an incurable form of vasculitis (inflammation of blood vessels) that affects the nose, lungs, kidneys, and other organs. Due to its end-organ damage, it is life-threatening and requires long-term immunosuppression.[1] five-year survival is up to 87%, with some of the mortality due to toxicity of rx. ...Read more

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What causes granulomatosis with polyangiitis (GPA) and microscopic polyangiitis (MPA)?

What causes granulomatosis with polyangiitis (GPA) and microscopic polyangiitis (MPA)?

The exact causes of GPA — formerly known as Wegener's granulomatosis — and MPA are unknown: GPA and MPA are both types of inflammation of the blood vessels (vasculitis). It is believed that one or more genetic and environmental factors, such as infections, allergic reactions, certain drugs and diseases, might trigger an abnormal immune system response that causes GPA and MPA symptoms. However, no specific infection or event has been identified as the cause. GPA and MPA develop when the immune system mistakenly identifies blood vessel cells as foreign invaders and attacks them. The vessels become inflamed, causing them to narrow or close off, disrupting the flow of blood to various organs and causing organ and tissue damage. No matter the cause, early diagnosis and treatment of GPA and MPA are essential for a full recovery. ...Read more

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What is lymphomatoid granulomatosis?

Granulomatosis: It is a lymphoproliferative disorder (lymphomatoid means lymphoma-like). The word granulomatosis denotes one of its microscopic character, polymorphic lymphoid infiltrates and focal necrosis within it. It usually involves lung, skin, and central nervous system. It is caused by the epstein barr virus (same virus causes mono). No proven treatment but research trials are being done at nih. ...Read more

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Is polyarteritis nodosa always an autoimmune disease?

Is polyarteritis nodosa always an autoimmune disease?

Polyarteritis nodosa: Pan ( poly arteritis nodosa) is a disease of unknown cause.It affects small to medium sized arteries reducing or cutting off blood supply to organs . Men are affected more than women between ages of 30 to 50 . In 25% of patients hepatitis b or c infection is seen. Small and medium arteries are attacked by immune cells . It is immune mediated and exact cause is not known. ...Read more

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Causes of wegeners granulomatosis and treatment?

Causes of wegeners granulomatosis and treatment?

Autoimmune disease: Like all autoimmune diseases, the cause is not really known, but likely a combination of genetic factors and environmental exposures (e.g., infections, chemicals, pollutants). Treatment depends on how severe disease it is. Typically steroids (e.g. Prednisone) and if severe, Cytoxan or rituxan (rituximab). If limited disease (just nasal/upper airway involvement), Methotrexate may be sufficient. ...Read more

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Tuberculosis cerebritis is curable?

Tuberculosis cerebritis is curable?

Perhaps: If tuberculosis gets into the brain, this can clearly be deadly unless immediate intervention is accomplished. Often the spread results from tuberculoma rupturing and causing a tuberculous meningitis, and if pupils dilate, may be terminal. But if diagnosis is mad early, meds to treat may really turn around. The risk is however, very high indeed. ...Read more

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Please advise what is wegener's granulomatosis?

Immune vasculitis: The antobodies found in the test and that cause the disease are directed against an antigen within neutrohils. Untreated, Wegener's (granulomatous angiitis for those who cannot forgive Dr. Wegener's being a German during WWII) is fatal. Nowadays it can be managed using cyclophosphamide and/or perhaps other powerful agents and most people eventually recover. ...Read more

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Is systemic lupus erythematosus fatal?

Sometimes.: Sle is generally treated with good response, but unfortunately it is sometimes fatal. ...Read more

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What is chronic cutaneous lupus erthremyphosis

See: Subacute cutaneous lupus is a subtype of lupus that can have a lupus and be associated with positive antibodies for sjogren's as well as thyroid disease. Rarely, does it ever transition to systemic lupus. Hope that helps. ...Read more

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What's mucha-habermann disease?

What's mucha-habermann disease?

Skin Disorder: Mucha-habermann disease (pityriasis lichenoides et varioliformis acuta) is a rare skin disorder of the arms & trunk that is usually seen in children & young adults. ...Read more

Dr. Moshe Lewis
46 doctors shared insights

Granulomatosis (Definition)

A process associated with a tissue reacton involving monocytes and tissue macrophages. Clasically this was seen in infections, like tuberculosis and some fungal processes. It is also seen and inflammatory and reactive ...Read more