Doctor insights on:
Weaning Off Methotrexate
Methotrexate was originally used in the early 1950's as a treatment for cancer but was also found to be effective in many other diseases including rheumatoid arthritis and psoriasis. It has anti inflammatory and immunosuppressive properties which make it an excellent first line therapy for RA ...Read more
I am on 20mg Methotrexate for Psoriasis for the last 10 years.Can I give it up without weaning off without side effects. Thanks?
Is it common practice to wean off plaquenil (hydroxychloroquine) for undifferentiated connective tissue disease if it didn't improve sx?Methotrexate was added & helps.
Recently diagnosed with mctd. Worst symptom is red swollen painful hands. On methylpredisolone 2mg daily which helped and plaquinil. Tried to wean off steroid and ended up back on it rheumatologist wants me to start SQ methotrexate. I'm on the fence... an
Mtcd+methotrexate: hello ~ I assume your indecision, not stated, is having to take MTX is an oncological or anti-cancer drug. MTX is a very good drug (of last resort) and most Rheums wont use it unless they have to. Note that PLAQUANIL has severe side effects on the eye, making frequent eye exams mandatory if taking it. There is no good solution but a good Rheum doc will optimise Rx to LEAST harmful for BEST RESULT. ...Read more
Standard therapy: Methotrexate was originally used in the early 1950's as a treatment for cancer but was also found to be effective in many other diseases including rheumatoid arthritis and psoriasis. It has anti inflammatory and immunosuppressive properties which make it an excellent first line therapy for RA and other rheumatologist diseases. ...Read moreSee 2 more doctor answers
Yes: NSIDs can be taken with Methotrexate. With or without Methotrexate, NSAIDs have many possible side effects and need to be used carefully. Gastrointestinal issues such as ulcers/gastritis can occur. Studies continue to show NSAIDs are associated with increased risks of cardiovascular side effects such as heart attacks and strokes. Routine labs are needed to watch for other side effects of both meds ...Read moreSee 1 more doctor answer
Methotrexate is a medicine that treats several kinds of cancer, including cancer of the blood, bone, lung, breast, head, or neck. Also treats rheumatoid arthritis and psoriasis (a skin disease).
Fluconazole prevents and treats certain fungus infections. Belongs to a class of drugs called antifungals. ...Read more