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Doctor insights on: Waldenstrom Macroglobulinemia In Children

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Can you tell me the main symptoms of waldenstrom macroglobulinemia?

Can you tell me the main symptoms of waldenstrom macroglobulinemia?

It is type of cancer: This condition affects your blood cells and lymph nodes. it is related to another blood cancer,called multiple myeloma.There is good treatment available for it. You will be best served by seeing a hematologist(Blood specialist) who can diagnose and treat you better. ...Read more

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What is the difference between multiple myeloma and Waldenstrom macroglobulinemia?

What is the difference between multiple myeloma and Waldenstrom macroglobulinemia?

Paraprotein: Waldenstrom's looks like a low-grade lymphoma rather unusual plasma cells, and produces IgM pentamer molecules instead of IgG or IgA monomers or free light chains. It tends to occupy lymph nodes rather than marrow. Hyperviscosity of the blood is likely to be the most troublesome feature. ...Read more

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Would normal CBC, metabolic panel, ESR, CRP, PT, aPTT, d-dimer make multiple myeloma or waldenstrom macroglobulinemia unlikely? Given a presumptive diagnosis of von Willebrand at age 31 with no known family history. Concerned it may be acquired form.

Would normal CBC, metabolic panel, ESR, CRP, PT, aPTT, d-dimer make multiple myeloma or waldenstrom macroglobulinemia unlikely? Given a presumptive diagnosis of von Willebrand at age 31 with no known family history. Concerned it may be acquired form.

Not right tests: If you wish to be tested for multiple myeloma or Waldenstrom, you should have serum protein electrophoresis and immunofixation electrophoresis and if needed similar studies on urine. It is not a do it yourself diagnosis and your doctor should order the tests, if warranted. ...Read more

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Are the symptoms of waldenstr_m macroglobulinemia bad?

Are the symptoms of waldenstr_m macroglobulinemia bad?

Perhaps: People with waldenstrom's macroglobulinemia usually go to their doctor because of lymph node enlargement. This is usually not painful. Because of the protein the lymphoma cells make, one might have a headache, shortness of breath or other symptoms. As the disease progresses, symptoms can worsen. In late stages, anemia and other low blood counts become more problematic. ...Read more

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What are the treatments for walton strom macroglobulinemia?

What are the treatments for  walton strom macroglobulinemia?

Plasmapheresis: If you have a large amount of IgM in your bloodstream and it is causing problems, for example with your nervous system, and you are offered plasmapheresis, then by all means accept it. If you are offered Rituximab or a autologous marrow transplant, get all the facts but consider these options especially if your disease progresses. ...Read more

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I have waldenstr_m macroglobulinemia and I no longer have a doctor or insurance?

I have waldenstr_m macroglobulinemia and I no longer have a doctor or insurance?

Seek help from .....: There are many options- contact yor local chapter of the leukemia & lymphoma society or the american cancer society to get information on local oncologists at free clinics in your area. Some hospitals with cancer programs can get you in help you obtain emergency medical assistance especially if you need treatment such as state medicaid. ...Read more

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What are some good concrete metrics in defining remission for waldenstrom's macroglobulinemia - in terms of bone marrow analysis and IgM level?

What are some good concrete metrics in defining remission for waldenstrom's macroglobulinemia - in terms of bone marrow analysis and IgM level?

50%, 90%, 100%: Confirmation of response in wm has been
adopted from response criteria for multiple
myeloma. See http://www.Iwmf.Com/docs/ghobrial_clincial_trials.Pdf
especially see tables xi, xii. The treatment of wm is aimed at control of symptomatic disease. Risk/benefits of various therapies are highly individualized based on patient and disease characteristics. ...Read more

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Is a tiny IgM kappa monoclonal protein migrating in beta2 region considered specific for waldenström's macroglobulinemia irrespective of size?

No. MGUS: Mgus = monoclonal gammopathy of unknown significance. Igm is associated more with waldenstrom's macroglobulinemia (vs igg, iga, igd, ige with multiple myeloma). More info on background is here: http://bloodjournal.Hematologylibrary.Org/content/109/12/5096.Full" rel="nofollow" ta. ...Read more

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Can a IgM kappa light chain monoclonal gammopathy turn into macroglobulinemia?

Can a IgM kappa light chain monoclonal gammopathy turn into macroglobulinemia?

IgM is macroglobulin: Macroglobulinemia is the term for monoclonal igm. However what you described is confusing/erroneous term, igm kappa is not light chain gammopathy. Igm kappa, by definition is macroglobulin. ...Read more

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I am wondering with normal SPEP, Bone marrow Biopsy, PET Scan All normal, high B2M is there chances for Myeloma or Waldenström's macroglobulinemia?

Yes: There is no test that will completely exclude nay diagnosis. In additon, b2m is a marker for all lymphoid disease (CLL, NHL, Hodgkin etc..) In any event, with the above negatvie studies the chances of you having lymphoma/myeloma missed is excedingly small ...Read more

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What is walden strom marcogulinemia?

What is walden strom marcogulinemia?

Low grade lymphoma: It is a disorder where one produces more antibody, specifically igm. This antibody is large so when in increased numbers can lead to several problems. These include what is called hyper viscosity syndrome. As there is too much of this protein, it tends to clog small arterioles and can lead to such things as mouth sores, kidney problems and other issues. The goal is keep the level down. ...Read more

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I am married in 1 year no children en problem in my health would you eat that type of food can be eat him in my husband and me?

I am married in 1 year no children en problem in my health would you eat that type of food can be eat him in my husband and me?

Chocolate : This is not scientific but neither is having babies! Try anything chocolate. Eat romantic foods. Avoid alcohol and stimulants. Relax. Enjoy being married without children. The more you relax and enjoy your spouse the better your marriage will be and the more prepared you we be to be a parent. You are learning patience and you will need it! OB doctors have solutions for you when wanted ...Read more

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Can children use Clobex?

Can children use Clobex?

Clobex/children: It is safe to use in kids 12 and older. Under age 12, it is a pretty hefty steroid to use for a kid. It is a steroid, and a fairly potent one at that. Kids can absorb it through their skin and it can then affect them as if they ingested it. I would use a lower potency steroid on a kid under 12, although there are occasions when a stronger one is needed - close monitoring is then needed as well ...Read more

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Can children use Betimol?

Can children use Betimol?

Yes: if monitored closely by a pediatric eye specialist

The medicine is used to reduce intra-ocular pressure caused by conditions like glaucoma ...Read more

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Can children use Periogel?

Can children use Periogel?

2 and over - yes: This product is used to help heal a mouth or gum injury. The key to safety is the ability of the child to spit it out after use.

http://drugsdb.eu/otc_drug.php?d=Periogel&m=Qnt%20Anderson,%20Llc&id=9784ca75-075d-4186-b49d-983f4a53d818.xml ...Read more

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Can children use Phoslyra?

Can children use Phoslyra?

Depends: Phoslyra is used to help reduce phosphate levels in end stage renal disease. If your child has renal disease and is working with a specialist this may be considered in the treatment plan. I would review your concerns with the MD who recommended the medication.

http://www.drugs.com/pro/phoslyra.html ...Read more

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Can children use Halonate?

Can children use Halonate?

Not Recommended: Greetings. I would not recommend the use of Halonate on a child if it was not prescribed by a Dermatologist. Because it is categorized as a "super high potency" topical steriod, it can have serious side effects when used incorrectly. High potency creams and ointments can be asorbed easily through the skin and cause malfunction to certain organs. Best regards. ...Read more

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Can children take Flo-PRED?

Can children take Flo-PRED?

Steroids: Flo-pred is a brand of prednisolone a steroid often used in children with asthma, colitis , and other disorders where an anti-inflammatory medication is used. ...Read more

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Can children use Triesence?

Can children use Triesence?

Specialist decision: Triesence is an injectable steroid into your eye to treat inflammation when steroid eye drops are not helpful. Use on a child would need to be monitored closely and be administered by an eye specialist with experience using this medication. It is not something I typically see in my practice so I suspect your child has a unique health challenge. Good luck!

http://www.drugs.com/triesence.html ...Read more

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Can children use Nexterone?

Can children use Nexterone?

Yes, but: only in certain situations. It is a cardiac drug used in life threatening cardiac arrhythmias. It is typically given via IV in critically ill patients. ...Read more

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Can children take Baycadron?

Can children take Baycadron?

Yes: also known as dexamethasone, a steroid commonly given for things like croup in children. ...Read more

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Can children take Serviflox?

Can children take Serviflox?

Serviflox in kids -: The answer to your question is yes and no. The medicine is ciprofloxacin. Generally we do not give this to pediatric patients because there is a risk for tendon problems in patients who have not reached full maturity. However, there are situations where the risk of this happening is outweighed by the need for the med - like in kids with Cystic Fibrosis Also, the ear drops are safe in kids! ...Read more

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What age should children smile?

What age should children smile?

About 1 month old: Babies begin to smile spontaneously at about 1 month of age. They begin to smile in response to your smile, face or voice at about 2 months of age. ...Read more

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Can children use Medihaler-EPI?

Can children use Medihaler-EPI?

Probably not: I have reviewed this product information as I have not heard of it. It's inhaled epinephrine which is not currently on the Pediatric asthma protocols. I would not advise it's use at this time.

http://www.drugs.com/pro/medihaler-epi.html ...Read more

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Will my children have this condition?

Will my children have this condition?

What condition ?: When you submit a question to the site please read it through before you send it. Understand that each question is set up individually. Your submissions are not linked. If you submit one question & a separate followup question, the followup question must have enough information to stand on it's own. ...Read more

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At what age is best to have children?

At what age is best to have children?

DEPENDS: If your main interest is avoiding chromosome defects, the age is the early to mid 20's. There is a slight increase under 16 and it increases every year after the mid 20's. If your interest in being financially and emotionally ready for the work involved, the late 20's to early 40's may be better.All pregnancies have a basic risk of unexpected outcome. Reviewing risk with a geneticist helps some. ...Read more

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What foods can little children choke on?

What foods can little children choke on?

Anything: Most often fruit such as grapes, pieces of hot dog and candy but anything that is not quickly broken down and cut into tiny pieces can be choked on. ...Read more