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Doctor insights on: Von Willebrands Disease

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What is von willebrand's disease?

What is von willebrand's disease?

Von Willebrand ....: Factor . Vwf is a glycoprotein important for primary hemostasis. It cross links collagen at a site of injury with gpib on platelets. Deficiency leads to failure of primary hemostasis (ie, bleeding). Vwf also protects fviii from degradation. Fviii also promotes clotting. So, vwf deficiency also causes secondary fviii dysfunction. Vwf def has many variants. Severity is variable. Most have type i. ...Read more

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What is von willebrand's disease ?

What is von willebrand's disease ?

A bleeding problem: Platelets stop bleeding by patching holes in blood vessels. von Willebrand factor is the glue that sticks platelets to those holes. If von Willebrand factor is low, or if the structure of VWF is abnormal, it doesn't stick platelets to the sites of bleeding. Most people have nosebleeds, gum bleeding, or bleeding after tooth extraction. There are 4 types of VW disease with different symptoms. ...Read more

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What is von willebrand's disease type 3?

What is von willebrand's disease type 3?

VonWillebrand type 3: This is severe von willebrand disease. These people may have a total absence of von willebrand factor, and factor viii levels are often less than 10%. Usually inherited in recessive manner (one affected gene from each parent who may not have symptoms). It is essential to see a pediatric hematologist for this disease. ...Read more

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Can you tell me about von willebrand's disease?

Bleeding disorder: VWD is bleeding disorder and come from parents and to confirm the diagnosis you should see hematology for blood test. ...Read more

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I need to know what is von willebrand's disease?

Bleeding disorder: Von willebrand disease is a condition that can cause extended or excessive bleeding. The cause of von willebrand disease is a deficiency in or impairment of a protein called von willebrand factor, an important component in your blood-clotting process. In general, it takes longer for people with von willebrand disease to form clots and stop bleeding when they're cut. ...Read more

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What are the symptoms of von willebrand's disease?

What are the symptoms of von willebrand's disease?

Bleeding: Von willebrand disease is a bleeding disorder. There are several types, but the most common type involves nosebleeds or heavy periods. It can also cause significant bleeding after a tooth extraction or tonsillectomy or other surgical procedure. ...Read more

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What is von willebrand's disease? What is the cure?

Bleeding disorder: This is relatively common hereditary bleeding disorder,the bleeding episodes can be corrected transiently by infusion of fresh or fresh-frozen plasma or cryoprecipitate. ...Read more

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What can you tell me about von willebrand's disease?

What can you tell me about von willebrand's disease?

Bleeding disorder: Vwd is a decrease in production (usually) of a specific protein required for clotting blood, called vw factor. The actual amount produced varies. Typical symptoms include nosebleeds, heavy periods, easy bruising and bleeding after surgeries. There are treatments for this disorder. This is type 1 and it is the most common bleeding disorder. ...Read more

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What is von willebrand disease?

What is von willebrand disease?

Bleeding disorder: Vwd is the most common inherited bleeding disorder. Von wiilebrand factor is a clotting protein that helps stabilize clots by helping to bind platelets together and also helps carry factor viii in the blood. In vwd, vw factor is either decreased or does not function appropriately. Clots will form but they are not stable, can easily fall apart/ dissolve, and bleeding will then occur. ...Read more

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What are the symptoms of von willebrand disease?

Bleeding: Von willebrand disease is a bleeding disorder. There are several types, but the most common type involves nosebleeds or heavy periods. It can also cause significant bleeding after a tooth extraction or tonsillectomy or other surgical procedure. ...Read more

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How do you get tested for von willebrand disease?

Blood tests: There are a few blood tests that help diagnose von willebrand disease. It is not always easy to diagnose. The levels that are measured can change with stress or illness, making it tough to know if you have the disease. Repeat testing is essential. ...Read more

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Is von willebrand disease considered risky for women?

Is von willebrand disease considered risky for women?

Not necessarily: "risky" is hard to define. Because menstrual bleeding is one of the more common problems women with VWD have, it is considered "riskier" for women than men. It is very possible to manage menstrual bleeding, as well as bleeding with childbirth very effectively, however. Once that happens, VWD is no riskier for women than it is for men. ...Read more

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Can I get Botox injections if I have Von Willebrand's disease?

Can I get Botox injections if I have Von Willebrand's disease?

Botox: As far as I know there is not contraindication. You may have a little bleeding at the injection site but it can be easily controlled with pressure or aluminum chloride. ...Read more

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I want to know what is the difference between von willebrand's disease and hemophilia?

I want to know what is the difference between von willebrand's disease and hemophilia?

Different but....: Related. Vwf is a glycoprotein important for primary hemostasis. It cross links collagen at a site of injury with gpib on platelets. Deficiency leads to failure of primary hemostasis (ie, bleeding). Vwf also protects fviii from degradation. Fviii partners with fix to activate fx to ultimately promote clotting. So, while different, fviii & vwf deficiency can have similar presentations. Simplified! ...Read more

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What happens if my girlfriend has von willebrand disease and I don't what's the chances of our children getting it?

50% in most cases: an overwhelming majority of von Willebrand Disease (VWD) is dominant, meaning that if you carry one gene, you have VWD. Supposing that your girl friend has one VWD on one chromosone, and the other is normal, the chance of her passing that VWD gene to your offspring would be 50%. Most patients with VWD have type 1 disease which is fully compatible with normal life span. ...Read more

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Can you tell me if my girlfriend has von willebrand disease and i don't what's the chances of our children getting it?

More info needed: Some von Willebrand is transmitted genetically and some is acquired by a medication or other factor. What type does your girlfriend have? Her doctor can tell her and then a discussion of potential transmission to offspring can occur. ...Read more

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Do you know of any person that has von willebrand disease and factor five disorder?My dr tells me I am unique. And i can't be treated for either one.

Why?: I agree that there are probably others out there with the same combination of problems. And this should not preclude any necessary therapy. If you have bleeding due to your vwd, treatment can be provided without greatly increasing your risk for developing a clot. Conversely, many patients with fv leiden (what i think you mean) don't need to take blood thinners, so VWD shouldn't be a problem. ...Read more

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How do you test for von willebrand's disease ?

VWD diagnosis : Requires special blood tests to look at factor viii levels, structure and function. ...Read more

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As a child, doctors thought I might have von willebrand disease.

As a child, doctors thought I might have von willebrand disease.

Interesting.: Von willebrand disease is a difficult disease to diagnose. The most typical form is type 1, generating low levels of protein. However, your body can make this protein, and usually the treatment is a medication that "stresses" the body, causing release of von willebrand protein. I have known of several people who have low levels during childhood and the levels normalize later in life. ...Read more

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