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Doctor insights on: Von Willebrand Factor Activity

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What does a low von willebrand factor (vwf) ag: 33 %, low vwf activity: 29 % and factor viii activity: 52 % result mean?

What does a  low von willebrand factor (vwf) ag: 33 %, low vwf activity: 29 % and factor viii activity: 52 % result mean?

VWD: First of all, these test need to be repeated at least one more time, prederably while you are off all medications. If persistently low, this may mean that you have von willibrand disease (VWD) which is a bleeding disorder. These are several types of VWD and more testing is needed to determine the type. You need to see a hematologist for this. Avoid any surgery and trauma. ...Read more

Dr. Joseph Torkildson
47 doctors shared insights

Von Willebrand (Definition)

Von Willebrand disease is caused by a deficiency of von Willebrand factor. Von Willebrand factor helps blood platelets clump together and stick to the blood vessel wall, which is necessary for normal blood clotting. There are several types ...Read more


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What does a low von willebrand factor (vwf) ag: 33 %, low vwf activity: 29 % and factor viii activity: 52 % result mean?

VWD: First of all, these test need to be repeated at least one more time, prederably while you are off all medications. If persistently low, this may mean that you have von willibrand disease (VWD) which is a bleeding disorder. These are several types of VWD and more testing is needed to determine the type. You need to see a hematologist for this. Avoid any surgery and trauma. ...Read more

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Is there a way to increase my von willebrand factor levels up w/o meds?

Is there a way to increase my von willebrand factor levels up w/o meds?

Von Willebrand Dz: The main thing that raises von willebrand factor levels is exposure to female hormones, whether through pregnancy or taking oral contraceptive pills or hormone replacement therapy. Please consult with your hematologist for further advice on this topic. ...Read more

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I have type 2 von willebrands, severe, unknown subtype. I only respond to humate p (factor viii and von willebrand factor). Is there anything else i can take to help with minor bleeds. ?

There are options: There are two other possibiliries that are approved "non-replacement" therapies for the treatment of VWD type 2a, in addition to humamte p there is Alphanate sd/ht. The other is called Koate dvi (factor viii) but this one is used in an off lable fasion for vwd. Read starting at page 50 here for more information. Only your hematologist should make any changes. http://www.nhlbi.nih.gov/guidelines/vwd/vwd.pdf. ...Read more

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Was taking a recombinant-derived fviii for hempohilia a and inhibitor appear. Finishing iti and doc says 2 try plasma fviii. Alphanate (factor viii and von willebrand factor) or koate and y?

Follow his advice: Development of recombinant factor v111 inhibitor those occur frequently after prolonged treatment and those make the treatment less effective. Hence your dr will recommend products to bypass the inhibition. ...Read more

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Von willebrand factor effect on pregnancy?

Von willebrand factor effect on pregnancy?

Bleeding risk: Von willebrand does not affect fertility, so getting pregnant is typically not an issue. Childbirth can be challenging with von willebrand due to the increased risk for bleeding. This can be managed by a hematologist and that risk can be lowered significantly. Good luck. ...Read more

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Do you know of any person that has von willebrand disease and factor five disorder?My dr tells me I am unique. And i can't be treated for either one.

Why?: I agree that there are probably others out there with the same combination of problems. And this should not preclude any necessary therapy. If you have bleeding due to your vwd, treatment can be provided without greatly increasing your risk for developing a clot. Conversely, many patients with fv leiden (what i think you mean) don't need to take blood thinners, so VWD shouldn't be a problem. ...Read more

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Can you tell me about von willebrand's disease?

Bleeding disorder: VWD is bleeding disorder and come from parents and to confirm the diagnosis you should see hematology for blood test. ...Read more

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What can you tell me about von willebrand's disease?

What can you tell me about von willebrand's disease?

Bleeding disorder: Vwd is a decrease in production (usually) of a specific protein required for clotting blood, called vw factor. The actual amount produced varies. Typical symptoms include nosebleeds, heavy periods, easy bruising and bleeding after surgeries. There are treatments for this disorder. This is type 1 and it is the most common bleeding disorder. ...Read more

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Is von willebrand disease considered risky for women?

Is von willebrand disease considered risky for women?

Not necessarily: "risky" is hard to define. Because menstrual bleeding is one of the more common problems women with VWD have, it is considered "riskier" for women than men. It is very possible to manage menstrual bleeding, as well as bleeding with childbirth very effectively, however. Once that happens, VWD is no riskier for women than it is for men. ...Read more

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Can I get Botox injections if I have Von Willebrand's disease?

Can I get Botox injections if I have Von Willebrand's disease?

Botox: As far as I know there is not contraindication. You may have a little bleeding at the injection site but it can be easily controlled with pressure or aluminum chloride. ...Read more

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How do you test for von willebrand's disease ?

VWD diagnosis : Requires special blood tests to look at factor viii levels, structure and function. ...Read more

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I am very anemic. Could I have von willebrand's disease and not know it?

I am very anemic. Could I have von willebrand's disease and not know it?

It's possible. : You don't mention if you are male or female. Women with VWD who have menorrhagia (very heavy periods) can develop severe anemia either acutely due to blood loss or more slowly due to iron deficiency, yet think their periods are "normal". Men on the other hand would generally recognize the amount of blood loss required to cause this as being abnormal. ...Read more

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Is there a genetic basis for von willebrand disease?

Is there a genetic basis for von willebrand disease?

Yes: Vwd is an inherited condition. It affects both males and females. If one parent has the most common type, type 1, then each child has a 50% chance of inheriting the disease. ...Read more

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Could people with von willebrand disease get tattoos?

Could people with von willebrand disease get tattoos?

Yes: Most people with von Willebrand's don't know they have it. If you have a severe form and are followed regularly by a hematologist, ask him/her first. Otherewise, go ahead. Be sure it's something you really and truly want. Best wishes. ...Read more

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What's the von willebrand's ddavp (desmopressin) test?

What's the von willebrand's ddavp (desmopressin) test?

Stimulaton test: Patients with type 1 VWD less vw factor than normal people. However, they store vwf normally in the cells that line their blood vessels. This can be released into the blood by certain drugs; one of these is ddavp (desmopressin). In a DDAVP (desmopressin) challenge the vwf level is measured, a dose of DDAVP (desmopressin) is given, and the level measured again to see if it goes up significantly. If so, DDAVP (desmopressin) can be used to control bleeding. ...Read more

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Can people with von willebrand disease get tattoos done?

It is possible, but: Depending on the severity of your disease, it is possible, but only in consultation with your hematologist. The severity of VWD is quite variable from patient to patient. If you really wanted to get a tattoo, you could pre-treat yourself with the appropriate medicine as if you were having an elective surgery, but you would have to pay for it out of pocket (i doubt insurance would cover it). ...Read more

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Could you donate blood if you have von willebrand disease?

Could you donate blood if you have von willebrand disease?

No: Most blood centers say no, mostly because the risk for you donating (venipuncture) is not trivial and impossible for the blood center to assess at the time of donation. You could always donate your time as a volunteer at a blood drive, however! ...Read more