Doctor insights on:
Von Willebrand Antigen
Can you tell me if my girlfriend has von willebrand disease and i don't what's the chances of our children getting it?
Possibly: With vwb, you may be at extra bleeding risk. It depends on the platelet count and the function of your blood clotting. So often your doctors will take special precautions. But anything can happen in surgery and with childbirth so being prepared is the most important thing. That being said, in most patients everything is fine. ...Read moreSee 1 more doctor answer
What does a low von willebrand factor (vwf) ag: 33 %, low vwf activity: 29 % and factor viii activity: 52 % result mean?
VWD: First of all, these test need to be repeated at least one more time, prederably while you are off all medications. If persistently low, this may mean that you have von willibrand disease (VWD) which is a bleeding disorder. These are several types of VWD and more testing is needed to determine the type. You need to see a hematologist for this. Avoid any surgery and trauma. ...Read more
VonWillebrand type 3: This is severe von willebrand disease. These people may have a total absence of von willebrand factor, and factor viii levels are often less than 10%. Usually inherited in recessive manner (one affected gene from each parent who may not have symptoms). It is essential to see a pediatric hematologist for this disease. ...Read more
Homozygous vWD: Pts with type 3 VWD have loss or mutations of both vwf genes, and produce almost no vwf protein. Clinically they behave like severe hemophilia a patients as their factor viii levels are very low as well, since vwf also carries factor viii in the blood. ...Read moreSee 1 more doctor answer
Bleeding disorder: Von willebrand disease is a condition that can cause extended or excessive bleeding. The cause of von willebrand disease is a deficiency in or impairment of a protein called von willebrand factor, an important component in your blood-clotting process. In general, it takes longer for people with von willebrand disease to form clots and stop bleeding when they're cut. ...Read more
A bleeding disorder.: It is the most common inherited bleeding disorder.Type 1 is mild , more symptomat in females with menorrhagia and mucous membrane bleeds DDAVP (desmopressin) , inhaler is effective. Type 3 severe , Joint bleeds in addition. Type 1 clotting protein is decreased but missing in type 3 and defective in type 2 ( several sub types). So the VW factor is to be given by infusion In most types 2 and 3 . ...Read more
Bleeding disorder: This is relatively common hereditary bleeding disorder,the bleeding episodes can be corrected transiently by infusion of fresh or fresh-frozen plasma or cryoprecipitate. ...Read more
Bleeding disorder: Vwd is the most common inherited bleeding disorder. Von wiilebrand factor is a clotting protein that helps stabilize clots by helping to bind platelets together and also helps carry factor viii in the blood. In vwd, vw factor is either decreased or does not function appropriately. Clots will form but they are not stable, can easily fall apart/ dissolve, and bleeding will then occur. ...Read moreSee 1 more doctor answer
No, unfortunately.: Von willebrands disease is inherited and present at birth. There are many people who have VWD and barely know it because it is so mild. Others have more symptoms, but it is rarely life threatening or life-shortening. ...Read more
It is possible for..: A person with a bleeding disorder like vwf def to get a tattoo, but precautions are warranted. If you normally utilize DDAVP (desmopressin) or similar adjunctive to address bleeding, it's advisable to administer doses the day of and following the tattoo to mitigate/prevent bleeding. Using a tattoo artist with designated training in infection control is essential. Not my cup of tea, but others have done it. ...Read more
Interesting.: Von willebrand disease is a difficult disease to diagnose. The most typical form is type 1, generating low levels of protein. However, your body can make this protein, and usually the treatment is a medication that "stresses" the body, causing release of von willebrand protein. I have known of several people who have low levels during childhood and the levels normalize later in life. ...Read moreSee 1 more doctor answer
It's possible. : You don't mention if you are male or female. Women with VWD who have menorrhagia (very heavy periods) can develop severe anemia either acutely due to blood loss or more slowly due to iron deficiency, yet think their periods are "normal". Men on the other hand would generally recognize the amount of blood loss required to cause this as being abnormal. ...Read moreSee 1 more doctor answer