Doctor insights on:
Vitamin B12 Deficiency Without Anemia
Not clear: No clear evidence for the causal-effect relationship between the two. PA is an autoimmue-mediated destruction of parietal cells in stomach, resuling in impairmnent of B12 absorption. Certainly it is possible that pernicious anemia may co-exist or exacerbate duodenitis via immune process or loss of balance in duodenal fluid, or anemia. But the causal-effect relationship is not well established. ...Read more
Please what's the difference between pernicious anemia and vitamin B12 deficiency. My iron levels are perfect. I'm getting injections for vitamin b12.
Intrinsic factor: Vitamin B12 is present in meat and animal protein foods. Absorption of B12 occurs in the intestine (ileum) and requires intrinsic factor (IF), made by stomach cells. In pernicious anemia, IF production is deficient, and results in anemia, a reduction in hemoglobin/hematocrit. One can be vitamin B12 deficient without becoming anemic and/or without having deficient IF. Best wishes:) ...Read more
I have vitamin B12 Deficiency not pernicious anemia. My doctor told me. My reading was 160. What is that number is it 160mcg.
It's on your report:
The lab report should have a reference value. Sometimes it is reported as nanograms per milliliter (ng/mL), or as picograms per milliliter (pg/mL)
1 picogram is equal to 0.001 nanograms, making the nanogram a larger unit.
when you take b12, the dose is usually in micrograms (mcg)
1 mcg is equal to 1000 nanograms
i had to look up all that, by the way ...Read more
My mom was diagnosed a few years ago with vitamin B12 deficiency/anemia. Could this be a genetic thing?
Not exactly.: Pernicious anemia as cause of B12 deficiency is an autoimmune disease. The tendency to develop autoimmune disease is genetic, but not specific for a particular condition. It is not like eye color where you can predict with certainty what will happen. Autoimmune disease is part genetic, but something else has to happen to trigger it. ...Read more
We don't: Megaloblastic anemia caused by B12 deficiency is treated with b12. Folate (folic acid) deficiency also causes meg. Anemia. Some with B12 deficiency are also deficient in b12, but if one has low B12 ; isn't deficient in folate (folic acid) there's no need to supplement with it. But it won't hurt to take folate (folic acid);if you're among the 1/3 of people with problems converting Folic Acid to it's active form you should take l-5-mthf. ...Read more
Hi I have vitamin B12 Deficiency. Doc didn't say pernicious anemia. Everyone said I'm going to get cancers. God im so scared. I've started injections?
B12 def: Are you vegetarian or vegan, they have B12 issues at times because B12 sources are animal. May also be ileitis or intestinal issues where B12 is absorbed (if not pernicious anemia) or dietary/ age. If you are on injections and you level are adequate (I like above 400) I would not be concerned, don't worry ...Read more
My doctor has told me I do not have pernicious anemia. I have vitamin B12 Deficiency. Blood test result was 160. So I have mild vitamin B12 Deficiency?
Get a consult: "Mild vitamin B12 deficiency" is like being "a little bit pregnant." It should not happen -- ESPECIALLY if you are, as you say, pregnant. If this happened because you are a vegetarian, reconsider or start supplementing now. Otherwise, you have a right & duty to know what's happening. Your primary care physician didn't communicate answers to you -- a 2nd physician's input is in order. ...Read more
My last 5 cbc, show's I do not anemia. But doctor ordered vitamin B12 test since I have family history of anemia. Can vitamin B12 deficiency be treated successfully? Is there always underlying cause?
Is it possible to treat vitamin B12 deficiency without taking suppliments, ie. Only through dietary changes?
Yes - See Links::
1) http://en. Wikipedia. Org/wiki/vitamin_b12_deficiency
2) http://www. Doctoroz. Com/videos/end-your-energy-crisis-vitamin-b12
3) http://chriskresser. Com/b12-deficiency-a-silent-epidemic-with-serious-consequences
3) http://www. Webmd. Com/food-recipes/guide/vitamin-b12-deficiency-symptoms-causes. ...Read more
B12 supplements: It is important to figure out why you are B12 deficient. This will also help to determine what treatment is most appropriate. For many, taking B12 supplements by mouth in high enough dose can overcome absorption problems (1000mcg/day). For others, B12 injections are needed, either short-term or lifelong. ...Read more
LACK OF ABSORPTION: B12 deficiency can be due to a lack of absorption or intake from diet. Since B12 is primarily found in animal products (e.g., dairy, egg, meat, etc.) vegetarians are more at risk. A deficiency is suspected when rbcs increase in size (e.g., high MCV and/or MCH in cbc) and can cause megaloblastic anemia. Symptoms can include fatigue and neuropathy. It is best corrected with methyl B12 by injection. ...Read more
Yes: If you have pernicious anemia with your vitamin B12 deficiency, you can have nervous system problems that can include incontinence and muscle spasms which can affect sleep. Treatment with intramuscular injections of vitamin B12 can help. If you have a mild deficiency but not pernicious anemia, it is less likely that sleep will be affected. ...Read more
Any one: Any primary care doctor can treat B12 deficiency. It used to be treated with injections but now can often be managed with or or sublingual B12. Levels need to be monitored by the doctor so see one right away if you have this condition. ...Read more
If not treated:
B-12 deficiency can cause peripheral neuropathy, problems with spinal cord dysfnctn (poor vibration and position sensations), and cognitive problems to the brain. Much may be reversible, but without timely treatment, problems will be persistent.
1000 mcg injections per month should suffice. ...Read more
Yes: In the early 19th century, scientists noted weakness and numbness with B12 deficiency. Recently, B12 has been shown to upregulate neurotrophic factors (chemicals [cytokines] that help nerve cells grow) & downregulate neurotoxic factors (chemicals that break down nerve cells). In other words, B12 helps nerve cells grow and prevents their destruction by naturally occurring brain chemicals. ...Read more
Required by nerves: This co-factor is needed by the nerves to stay healthy. Each nerve cell has a self repair system that relies on a variety of nutrients in our diet to provide the needed material to keep the walls intact and the cell working. Lack of B12 eventually causes that repair system to start breaking down and nerve cells malfunction or degenerate, leading to neurologic symptoms. ...Read more
Yes: But by all means continue what is likely to be lifetime treatment for B12 deficiency. If you have pernicious anemia, monthly injections will safe your health and life. If you are a vegetarian, please learn how to supplement to protect your health. If you have B12 deficiency from some other cause, it's likely to be a lifetime management issue. You deserve to enjoy your tea. Stay pro-active. ...Read more
It depends...: This depends on the cause of the deficiency. If it's due to a lack of B12 in your diet (b12 is primarily found in animal-derived foods) then taking a multivit. With B12 will help. However, many cases of B12 deficiency are caused by difficulty absorbing it, a condition called pernicious anemia. In that case, oral B12 won't help & you need injections &/or sublingual b12, ideally as methylcobalamin. ...Read more
Is there any test or scan to find out permanent nerve damage occurring due to vitamin B12 deficiency?
Yes: Usually in a young person with adequate replacemnt therapy (for life) the problems resolve. Somatosensory evoked potentials for cord involvemnt, ncv for periperal nerve involvment, cognitive testing and blood tests (cbc and b12) are available if problems persist beyond 1 year. Be sure to keep your serum B12 level above 350 or preferably above 450 if you've suffered neurological injury. ...Read more
I've had symptoms of vitamin B12 deficiency for years, does it mean that ill have permanent nerve damage?
I read that vitamin B12 deficiency can cause permanent nerve damage if left untreated for months. Is it true.?
Can vitamin B12 deficiency or a congenital B12 absorption problem cause my 10 year old to still be wetting his pants?
Is it possible to have a vitamin B12 deficiency if your serum level is 250 p/mol? Have every symptom plus high MCV and mch
As a matter of fact yes: I cannot go into the complex details, but I had two young patient's years ago, both of whom had elevated blood levels of vitamin B12. But both of them also had evidence of thiamin deficiency that would result in deficiency of energy. I concluded that vitamin B12 was collecting in the blood and not being used in metabolism. Try a supplement of thiamin and see whether the vitamin B12 levels come down. ...Read more
I was suffering from severe vitamin B12 deficiency until discovered recently. It left me with very weak body. How do I start gaining weight?
Do not worry: B-12 deficiency can be reversed as the levels rise in your body. Your weakness could well be due to the effect on the peripheral nerves, and as things stabilize, you will regain strength. Perhaps get both a dietician and personal trainer involved. Presume you are getting regular injections, but might add the medical food metanx to stabilize a bit faster. ...Read more