Doctor insights on:
Vitamin B12 Deficiency Gastric Bypass
YES!: Ppi's make it difficult for us to absorb B12 as gastric hydrochloric acid is needed to absorb B12 & minerals as well as digest protein. These drugs are dangerous to take for more than a few weeks! they increase risk of osteoporosis & serious infections. See http://bit.Ly/1607tg3 re: B12 & http://bit.Ly/1b1avqs & http://bit.Ly/1ach2tw re: the serious hazards of ppi's & safe &superior alternatives. ...Read more
No: It's absorbed readily as long as the small intestine is basically intact. Here's a recent scientific review. http://www.ncbi.nlm.nih.gov/pmc/articles/pmc3573592/. ...Read more
Well: Most people with pernicious anemia or atrophic gastritis will not absorb vitamin b12. The stomach symptoms you describe could be related to gastritis. However the deficiency of vitamin D should not cause your symptoms. Good luck, please see your doctor for more testing and answers ...Read more
We don't: Megaloblastic anemia caused by B12 deficiency is treated with b12. Folate (folic acid) deficiency also causes meg. Anemia. Some with B12 deficiency are also deficient in b12, but if one has low B12 ; isn't deficient in folate (folic acid) there's no need to supplement with it. But it won't hurt to take folate (folic acid);if you're among the 1/3 of people with problems converting Folic Acid to it's active form you should take l-5-mthf. ...Read more
Fairly: B12 def more common. Ideal lab value for serum B12 is 800 or more. Possibly due to gluten sensitivity which can damage gut lining and promote malabsorption. Also hypothyroidism can cause decreased stomach acid which can impair digestion and absorption. Take methylcobalamin supplements. ...Read more
Serum b12> 1999 mma 0.4, homocysteine high 19. No folate (folic acid) or iron deficiency normocytic anemia not responding to procrit. Is this an absorption issue?
Anemia: can be caused by blood loss or bone marrow suppression as well. More information is needed ( how long have you had a normal iron, folate (folic acid) and b12 level. What is your reticulocyte count ? ( is your bone marrow producing new RBC's) ? How low is your HCT and has it come up or gone down with B12. Is the RDW elevated ( do you put out large and small RBC's at the same time? Any blood loss ? ...Read more
Not clear: No clear evidence for the causal-effect relationship between the two. PA is an autoimmue-mediated destruction of parietal cells in stomach, resuling in impairmnent of B12 absorption. Certainly it is possible that pernicious anemia may co-exist or exacerbate duodenitis via immune process or loss of balance in duodenal fluid, or anemia. But the causal-effect relationship is not well established. ...Read moreSee 2 more doctor answers
Can IBS patients absorb nutrients from supplements as NT from food causing B12 & vitamin d defiency?
Can acid reflux worsen by taking biotin, b12, omega 3 fish tabs. vitamin k2 , buffered vitamin c,vitamin d3 have Barrett's Esophagus and a hernia.
Possibly fish oil: Fats including fish oil can sometimes aggravate reflux; this is less likely if taken with food. But certain supplements are proven beneficial for reflux, esp. melatonin. See http://www.greenmedinfo.com/blog/5-natural-heartburn-remedies-proven-beat-drugs and http://www.denvernaturopathic.com/MelatoninandGERD.htm and http://tinyurl.com/p88fxjm ...Read more
Please what's the difference between pernicious anemia and vitamin B12 deficiency.my iron levels are perfect.I'm getting injections for vitamin b12.
Intrinsic factor: Vitamin B12 is present in meat and animal protein foods. Absorption of B12 occurs in the intestine (ileum) and requires intrinsic factor (IF), made by stomach cells. In pernicious anemia, IF production is deficient, and results in anemia, a reduction in hemoglobin/hematocrit. One can be vitamin B12 deficient without becoming anemic and/or without having deficient IF. Best wishes:) ...Read more
Wt loss, low iron : Could be from a vast number of possibilities. This question requires more information. A good history, physical exam and scrutiny of current , past and future bloodwork will all help piece together this puzzle. In general low iron in healthy premenopausal women is usually from menstruation or pregnancy. The weight loss is somewhat worrisome. Highly recommend a formal consultation with a doctor. ...Read more
Not likely: Irritable bowel syndrome (IBS) is characterized by bloating, abdominal pain, diarrhea, and/or constipation. The colon appears normal when examined on colonscopy. Because the lining is normal, absorption of nutrients is not impaired by IBS. Lack of vitamin D and B-12 can be due to lack of absorption due to other illnesses, or simply lack of sufficient ingestion via diet-B-12, and lack of sun-vitD. ...Read more
Achlorhydria B12: You need to have acid in the stomach to assist with the the absorption of B12 (too technical to explain here). Without acid due to an acquired condition such as achlorhydria or to medication affects (from proton pump inhibitors which are commonly prescribed), you can develop B12 deficiency. ...Read moreSee 1 more doctor answer
Previous ida. Now high B12 and folate (folic acid) levels. Ferritin result is not back. Significant hair loss and sob? Could high folate (folic acid) mask B12 deficiency? Thx
Masks anemia only: High folate (folic acid) can mask megaloblastic anemia caused by B12 deficiency but does not affect B12 levels. The high B12 levels you have are proof that you don't have B12 deficiency. I don't know what ida is. Hair loss ; sob can have many causes. It sounds like you are being evaluated for possible causes. ...Read more
58+ F Hb 10.8, RBC "Predominantly macrocytic normochromic with macroovalocytes". Ferritin 100 ng/ml, B12 894 pg/ml, Folic Acid 12.3 ng/ml.Why Anemia ?
Hg 10.8 macrocytic: Tested methylmalonic acid? Homocystine,? they are usually elevated before B12 goes down, though your B12 is pretty normal. Are you on any medications? metformin? HIV? alcohol? Hypothyroidism, liver disease , COPD, G6PD, hemolysis, malabsorption ( usually have low B12 as well) can cause it as well. http://www.aafp.org/afp/2009/0201/p203.html f/u/ w/ hematology ...Read more
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